AM-694
Grundinformationen
- CAS
1346600-15-4- Standard-SMILES
O=C(c1ccccc1I)c1cn(CCCCCF)c2ccccc12- InChIKey
LFFIIZFINPPEMC-UHFFFAOYSA-N- Summenformel
- C20H19FINO
- Durchschnittliche Molmasse
- 435,3 g/mol
Überblick
1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole is a member of the class of indoles that is 1H-indole which is substituted at position 1 by a 5-fluoropentyl group and a position 3 by an o-fluorobenzoyl group. It is a selective agonist for the CB1 cannabinoid receptor; Ki values for the CB1 and CB2 receptors are 0.08 and 1.44 nM, respectively. It has a role as a cannabinoid receptor agonist. It is a member of indoles, an organoiodine compound, an organofluorine compound, a synthetic cannabinoid and an aromatic ketone.
Namen und Bezeichner
- Bevorzugter Name
- AM-694
- IUPAC
- [1-(5-fluoropentyl)indol-3-yl]-(2-iodophenyl)methanone
- Englischer Name
- AM-694-d4
- Summenformel
- C20H19FINO
- Molmasse
- 435.2738332
Namen und Synonyme
AM-6941-(5-fluoropentyl)-3-(2-iodobenzoyl)indoleAM694AM 6946RK7KN7L1ODEA No. 7694J2.929.919FCHEBI:1380171-[(5-Fluoropentyl)-1H-indol-3-yl]-(2-iodophenyl)methanone1-((5-FLUOROPENTYL)-1H-INDOL-3-YL)-(2-IODOPHENYL)METHANONEMETHANONE, (1-(5-FLUOROPENTYL)-1H-INDOL-3-YL)(2-IODOPHENYL)-AM694 cpd
Weitere Namen anzeigen
AM-694-d41-(5-Fluoropentyl)-3-(2-iodobenzoyl-d4)indole[1-(5-Fluoropentyl)-1H-indol-3-yl](2-iodophenyl-d4)Methanone
RefChem:556857335161-03-0UNII-6RK7KN7L1O[1-(5-Fluoropentyl)-1H-indol-3-yl](2-iodophenyl)methanone[1-(5-fluoropentyl)indol-3-yl]-(2-iodophenyl)methanoneSCHEMBL16755254SCHEMBL29385295SCHEMBL29567887
Datenbank-Bezeichner
- CAS
1346600-15-4- ChEBI
CHEBI:138017- UNII
- 6RK7KN7L1O
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 5,3
- Polarare Oberfläche (TPSA)
- 22 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 7
- Schwere Atome
- 24
- Formalladung
- 0
- Komplexität
- 418
Experimentelle und physikochemische Eigenschaften
Drugs
DEA NFLIS-Drug Category -> Synthetic Cannabinoids
DEA Schedule I Controlled Substance -> Cannabimimetic agents
Synthetic Cannabinoids
Pharmaceuticals -> Synthetic Cannabinoids or Psychoactive Compounds
Collision Cross Section181.96 Ų [M+H]+
Physikochemische Eigenschaften
- Löslichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- Off-White to Pale Yellow
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory InformationDEA schedule I controlled substance
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological ClassificationCompounds that interact with and stimulate the activity of CANNABINOID RECEPTORS.
Anwendungen
VerwendenThe labelled analogue of a synthetic cannabimimetic indole derivative which acts as a potent and selective agonist for the cannabinoid receptor CB1.
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