Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-
Grundinformationen
- CAS
58001-19-7- Standard-SMILES
CO[C@]12C[C@H](COC(=O)c3cncc(Br)c3)CN(C)[C@@H]1Cc1cn(C)c3cccc2c13- InChIKey
YSEXMKHXIOCEJA-HWXJYTLHNA-N- Summenformel
- C24H26BrN3O3
- Durchschnittliche Molmasse
- 484,39 g/mol
Namen und Bezeichner
- Bevorzugter Name
- Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-
- Englischer Name
- Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-
- Summenformel
- C24H26BrN3O3
- Molmasse
- 484.39
Namen und Synonyme
IsoergolineIsonicergolineNicergoline EP Impurity F(RSS)N-Nitroso Betahistine Para IsomerErgoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-((6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate(6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate (isonicergoline)
Datenbank-Bezeichner
- CAS
58001-19-7
Eigenschaften
Physikochemische Eigenschaften
- Siedepunkt
- 594.4 · 594.4±50.0 °C(Predicted)
- Dichte
- 1.47 · 1.47±0.1 g/cm3(Predicted)
- pka
- 6.33 · 6.33±0.40(Predicted)
- InChIKey
- YSEXMKHXIOCEJA-HWXJYTLHNA-N
- SMILES
- O([C@]12C[C@H](COC(C3=CN=CC(Br)=C3)=O)CN(C)[C@]1([H])CC1=CN(C)C3=CC=CC2=C13)C |&1:1,3,18,r|
Chemie und Industrie
Anwendungen
Verwenden8-epi Nicergoline is an impurity of Nicergoline (N394550) which is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.
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郑州汇聚化工有限公司0371-53399770 18037166334 · [email protected]
江苏艾康生物医药研发有限公司025-66061636 19370895928 · [email protected]
南京望知星医药科技有限公司18569809817 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]
济南启源生物科技有限公司18766124282; 18766124282 · [email protected]
希瓦生物科技（广州）有限公司13268215580 · [email protected]
上海柯维化学技术有限公司021-64609169 18901607656 · [email protected]
宝鸡缔都医药化工有限公司029-81145305 17791533577 · [email protected]
Moxin Chemicals
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