Biotinyl tyramide
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Grundinformationen
- CAS
41994-02-9- Standard-SMILES
O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)NCCc1ccc(O)cc1- InChIKey
VZWXNOBHWODXCW-ZOBUZTSGSA-N- Summenformel
- C18H25N3O3S
- Durchschnittliche Molmasse
- 363,5 g/mol
Namen und Bezeichner
- Bevorzugter Name
- Biotinyl tyramide
- IUPAC
- 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-(4-hydroxyphenyl)ethyl]pentanamide
- Englischer Name
- Biotinyl tyramide
- Summenformel
- C18H25N3O3S
- Molmasse
- 363.47
Namen und Synonyme
Biotinyl tyramide41994-02-9N-(4-Hydroxyphenethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamideBiotin-tyramide(3aS,4S,6aR)-Hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamideMFCD279530265-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-(4-hydroxyphenyl)ethyl]pentanamide1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-, (3aS,4S,6aR)-Biotin-PhenolBiotinyltyramidebiotinyl tyramineN-(4-Hydroxyphenethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
Weitere Namen anzeigen
Biotinyl TSABiotin TyramideD-(+)-Biotin-tyramine amideBiotinyl tyramide, 10 mM in DMSOBiotin-Phenol, BP, Biotinyl-TyramineTSA,Biotinyl tyramide,inhibit,Inhibitor(3aS,4S,6aR)-hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-1H...
Probes2_000007Biotin-Phenol,Biotin Phenolorb1218043orb1307106SCHEMBL4315244N-(4-Hydroxyphenethyl)biotinamideBiotinyl tyramide, >=97% (HPLC)STL544773
Datenbank-Bezeichner
- CAS
41994-02-9- Nikkaji
- J933.497A
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- XLogP
- 1,7
- Polarare Oberfläche (TPSA)
- 116 Ų
- H-Brücken-Donoren
- 4
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 8
- Schwere Atome
- 25
- Formalladung
- 0
- Komplexität
- 468
Physikochemische Eigenschaften
- Siedepunkt
- 735.8 · 735.8±60.0 °C(Predicted)
- Dichte
- 1.227 · 1.227±0.06 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C
- Löslichkeit
- Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 20 mg/ml)
- pka
- 10.01 · 10.01±0.15(Predicted)
- Aggregatzustand
- solid
- Farbe
- White
- Stabilität
- 1 year · Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
- InChIKey
- VZWXNOBHWODXCW-ZOBUZTSGSA-N
- SMILES
- C1(=O)N[C@]2([H])[C@H](CCCCC(NCCC3=CC=C(O)C=C3)=O)SC[C@]2([H])N1
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- wgk
- WGK 3
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Anwendungen
BeschreibungBiotinyl tyramide is a reagent that has been used for tyramide signal amplification (TSA) via catalyzed reporter deposition (CARD). In CARD, a reporter enzyme, such as horseradish peroxidase (HRP) conjugated to a secondary antibody, is bound to the target of interest and catalyzes the covalent deposition of biotinyl tyramide to the sample. The sample is then probed by a detector, such as streptavidin-HRP, allowing detection via chromogenic or fluorescent methods. Biotinyl tyramide has been used in immunohistochemistry, ELISA, Western blot, and in situ hybridization applications.
VerwendenBiotinyl Tyramide is a Biotin (B389040) derivative, a growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue.
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