Monatepil
Grundinformationen
- CAS
132019-54-6- Standard-SMILES
O=C(CCCN1CCN(c2ccc(F)cc2)CC1)NC1c2ccccc2CSc2ccccc21- InChIKey
WFNRNNUZFPVBSM-UHFFFAOYSA-N- Summenformel
- C28H30FN3OS
- Durchschnittliche Molmasse
- 475,6 g/mol
Überblick
Monatepil is a dibenzothiepine.
Namen und Bezeichner
- Bevorzugter Name
- Monatepil
- IUPAC
- N-(6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-4-[4-(4-fluorophenyl)piperazin-1-yl]butanamide
- Englischer Name
- Monatepil
- Summenformel
- C28H30FN3OS
- Molmasse
- 475.62
Namen und Synonyme
Monatepil103377-41-9monatepiloDTXSID3048811N4MMI0J7PWDTXCID60287371-Piperazinebutanamide, N-(6,11-dihydrodibenzo(b,E)thiepin-11-yl)-4-(4-fluorophenyl)monatepilum11-((4-(4-(4-fluorophenyl)-1-piperazinyl)butyryl)amino)-6,11-dihydrodibenzo(b,e)thiepin maleateRefChem:159485(+-)-N-(6,11-DIHYDRODIBENZO(B,E)THIEPIN-11-YL)-4-(P-FLUOROPHENYL)-1-PIPERAZINEBUTYRAMIDE132019-54-6
Weitere Namen anzeigen
N-(6,11-Dihydrodibenzo[b,e]thiepin-11-yl)-4-(4-(4-fluorophenyl)piperazin-1-yl)butanamideMonatepil [INN]N-(6,11-dihydrobenzo[c][1]benzothiepin-11-yl)-4-[4-(4-fluorophenyl)piperazin-1-yl]butanamideNCGC00183837-01(+/-)-N-(6,11-Dihydrodibenzo(b,E)thiepin-11-yl)-4-(p-fluorophenyl)-1-piperazinebutyramide1-Piperazinebutanamide, N-(6,11-dihydrodibenzo[b,e]thiepin-11-yl)-4-(4-fluorophenyl)-Monatepil [WHO-DD]N-(6,11-Dihydrodibenzo[b,e]thiepin-11-yl)-4-[4-(4-fluorophenyl)piperazin-1-yl]butanamide
Datenbank-Bezeichner
- CAS
132019-54-6- ChEMBL
CHEMBL172853
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 4,8
- Polarare Oberfläche (TPSA)
- 60,9 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 5
- Frei drehbare Bindungen
- 6
- Schwere Atome
- 34
- Formalladung
- 0
- Komplexität
- 650
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
Anwendungen
VerwendenAntianginal; antihypertensive.
Anbieter2 Anbieter
Alchem Pharmtech,Inc.8485655694 · [email protected]
重庆卡兰医药有限公司[email protected]
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