N-(1,1-Dimethyl-3-oxobutyl)acrylamide
2873-97-4C=CC(=O)NC(C)(C)CC(C)=OOMNKZBIFPJNNIO-UHFFFAOYSA-NDiacetone acrylamide appears as white crystals. (NTP, 1992)
2873-97-4Very soluble (NTP, 1992)
Highly sol in water and most organic solvents
Soluble in chloroform
248 °F at 8 mmHg (NTP, 1992)
120 °C @ 8 mm Hg
135 to 136 °F (NTP, 1992)
57-58 °C
Diacetone acrylamide appears as white crystals. (NTP, 1992)
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This chemical does not meet GHS hazard criteria for 18% (65 of 362) of reports.
Warning
H302 (82%): Harmful if swallowed [Warning Acute toxicity, oral]
P203, P264, P270, P280, P301+P317, P318, P330, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 362 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
Chemical: 2-Propenamide, N-(1,1-dimethyl-3-oxobutyl)-
2-Propenamide, N-(1,1-dimethyl-3-oxobutyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Propenamide, N-(1,1-dimethyl-3-oxobutyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: N-(1,1-dimethyl-3-oxobutyl)acrylamide (EC: 220-713-2)
2-Propenamide, N-(1,1-dimethyl-3-oxobutyl)-: Does not have an individual approval but may be used under an appropriate group standard
Used to make coatings, laminates, sealers, adhesives, and lubricating oils; to impart water tolerance and vapor permeability to copolymer films; as cross-linking agent in polyester resins; in color photography; in orthopedic bandages; in air sprays; [HSDB] Used as adhesion improver for cellulosics, concrete, and glass; [Hawley]
Textiles (Fiber & Fabric Manufacturing) [Category: Industry]
In mfr of coatings, laminates, sealers, adhesives, lubricating oils
Imparts water tolerance and vapor permeability to copolymer films; cross-linking agent in polyester resins; color photography
ORTHOPEDIC BANDAGE COMPRISING DIACETONE ACRYLAMIDE
IN AIR SPRAYS
2023: 1,000,000 - <2,500,000 lb
(1977) NOT PRODUCED COMMERCIALLY IN US
(1979) NOT PRODUCED COMMERCIALLY IN US
REACTION OF ACRYLONITRILE WITH ACETONE IN PRESENCE OF CONCENTRATED SULFURIC ACID; REACTION OF ACRYLONITRILE WITH 1,1-DIMETHYL-3-OXOBUTANOL VIA RITTER REACTION
Prepd by reaction of acrylonitrile with acetone in presence of concn sulfuric acid: Coleman et al, J Polym Sci 3a, 1601 (1965); Coleman, US patent 3,277,056 (1966 to Lubrizol).
N-Substituted acrylamides may also be prepared from acetylene, carbon monoxide, and an amine using an iron or nickel carbonyl catalyst.
Paint and Coating Manufacturing
2-Propenamide, N-(1,1-dimethyl-3-oxobutyl)-: ACTIVE
Similar to acrylic esters in polymerization behavior. Forms high mol wt polymers in bulk, soln, or emulsion. Esp suitable for electropolymerization.
Wird geladen…
DTXSID1024916CHEMBL3183854Large Crystals; Dry Powder; Liquid
White hygroscopic solid; [Merck Index] White or yellow crystalline solid; [MSDSonline]
HAS LONG SHELF LIFE; SHOWS NO POLYMERIZATION ON PROLONGED STORAGE.
50% NEUTRAL WATER SOLN IS STABLE @ PH 7.5-7.7 FOR UP TO 6 MO; HIGHLY REACTIVE VINYL MONOMER.
DIACETONE ACRYLAMIDE forms polymers in solution, in bulk, or in emulsion. May react vigorously with strong oxidizing agents. Can react exothermically with reducing agents (such as alkali metals and hydrides) to release gaseous hydrogen. May react exothermically with both acids and bases. May undergo autoxidation upon exposure to the air to form explosive peroxides.
Acute Tox. 4 (82%)
Acute toxicity (Oral) - Category 4
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/
LD50 Rat oral 1770 mg/kg
LD50 Mouse oral 1303 mg/kg
VerwendenDiacetone acrylamide is used in epoxy resin, acryl emulsion, water based paints, waste water treatment, photosensitive resins, waterborne coatings and gel electrophoresis. It is also used in the manufacture of permanent press fabrics.