(2R,3R,4S,5R)-2-(4-Amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Grundinformationen
- CAS
750598-20-0- Standard-SMILES
Nc1ncnc2c1c(F)cn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O- InChIKey
KRRZKBNCONNKPI-IOSLPCCCSA-N- Summenformel
- C11H13FN4O4
- Durchschnittliche Molmasse
- 284,24 g/mol
Namen und Bezeichner
- Bevorzugter Name
- (2R,3R,4S,5R)-2-(4-Amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- IUPAC
- (2R,3R,4S,5R)-2-(4-amino-5-fluoropyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
- Englischer Name
- 4-Amino-5-fluoro-7-(-D-ribofuranosyl)-7H-pyrrolo[2.3-d]-pyrimidine
- Summenformel
- C11H13FN4O4
- Molmasse
- 284.24
Namen und Synonyme
750598-20-05-fluorotubercidin(2R,3R,4S,5R)-2-(4-Amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolMFCD30471837CHEMBL4587788C11H13FN4O4(2R,3R,4S,5R)-2-{4-amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol(2R,3R,4S,5R)-2-(4-amino-5-fluoropyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diolSCHEMBL6509887BDBM50536665AKOS030628125AS-74926
Weitere Namen anzeigen
5-Fluoro-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-fluoro-7-β-D-ribofuranosyl-4-Amino-5-fluoro-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine4-Amino-5-fluoro-7-(-D-ribofuranosyl)-7H-pyrrolo[2.3-d]-pyrimidine(2R,3R,4S,5R)-2-(4-amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol*(2R,3R,4S,5R)-2-(4-amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol(WXC03258)
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -1,2
- Polarare Oberfläche (TPSA)
- 127 Ų
- H-Brücken-Donoren
- 4
- H-Brücken-Akzeptoren
- 8
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 20
- Formalladung
- 0
- Komplexität
- 365
Physikochemische Eigenschaften
- Schmelzpunkt
- 221 · 221-222 °C
- Siedepunkt
- 650.2 · 650.2±55.0 °C(Predicted)
- Dichte
- 1.99 · 1.99±0.1 g/cm3(Predicted)
- pka
- 12.31 · 12.31±0.70(Predicted)
Chemie und Industrie
Anwendungen
VerwendenSynthesis and biological activity of 5-Fluorotubercidin were examined. No antibacterial activity was observed. Increased activity of 5-Fluorotubercidin over tubercidin was observed against L-1219 cells and toxicity in fibroblast cells was reduced.
Anbieter11 Anbieter
韶远科技（上海）有限公司4000665055 · [email protected]
杭州璟皓生物科技有限公司（原河南辛迪加生物）17513242016 · [email protected]
Labnetwork lnc.+86-27-50766799 +86-18062016861 · [email protected]
上海鑫科泰生物科技有限公司18043446684 · [email protected]
杭州六可生物科技有限公司+86-571-86912261 19975279805 · [email protected]
济南药研药物化学有限公司[email protected]
襄阳紫宸生物医药科技有限公司19357386183 · [email protected]
范德(北京)生物科技有限责任公司15911056312 · [email protected]
南京美韬医药科技有限公司[email protected] · [email protected]
上海凯为化学科技有限公司021-58461859 15821823057 · [email protected]
浙江天酶生物工程有限公司19967302939 · [email protected]
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