4-Oxo-4,4a-dihydro-1,10-phenanthroline-3-carboxylic acid
Grundinformationen
- CAS
331830-20-7- Standard-SMILES
O=C(O)C1=CN=C2c3ncccc3C=CC2C1=O- InChIKey
YZRSIMPDMZRLJK-UHFFFAOYSA-N- Summenformel
- C13H8N2O3
- Durchschnittliche Molmasse
- 240,21 g/mol
Namen und Bezeichner
- Bevorzugter Name
- 4-Oxo-4,4a-dihydro-1,10-phenanthroline-3-carboxylic acid
- IUPAC
- 4-oxo-4aH-1,10-phenanthroline-3-carboxylic acid
- Englischer Name
- 4-Oxo-1,4-dihydro-[1,10]phenanthroline-3-carboxylic acid
- Summenformel
- C13H8N2O3
- Molmasse
- 240.21
Namen und Synonyme
SCHEMBL139060194-Oxo-4,4a-dihydro-1,10-phenanthroline-3-carboxylic acid1,4-dihydrophenonthrolin-4-one-3-Carboxylic acidorb1306255SCHEMBL29997251AKOS040744897MS-23399PD1570793-Acetyl-1H-[1,10]phenanthrolin-4-oneHY-121172CS-0079584EC-000.2078
Weitere Namen anzeigen
1,4-DPCA4-DPCA1,4-DPCA, 10 mM in DMSOTVBAVFFTADCWKG-UHFFFAOYSA-N4-Oxo-1,4-dihydro-[1,10]phenanthroline-3-carboxylic acid1,10-Phenanthroline-3-carboxylic acid, 4,4a-dihydro-4-oxo-HIF-PH,HIF/HIF Prolyl-Hydroxylase,HIF-1α,HIFs,FIH,P4HA1,P4HA2,1,4DPCA,healing,Inhibitor,Hypoxia-inducible factors,1,4 DPCA,wound,inhibit,1,4-DPCA,P4HA3
G13380T21653J-0190714,4a-Dihydro-4-oxo-1,10-phenanthroline-3-carboxylic Acidinverted exclamation mark-dihydro-4-oxo-1,10-phenanthroline-3-carboxylic acid
Datenbank-Bezeichner
- CAS
331830-20-7- Nikkaji
- J1.436.901E
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 1,7
- Polarare Oberfläche (TPSA)
- 79,6 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 5
- Frei drehbare Bindungen
- 1
- Schwere Atome
- 18
- Formalladung
- 0
- Komplexität
- 504
Physikochemische Eigenschaften
- Siedepunkt
- 419.5 · 419.5±45.0 °C(Predicted)
- Dichte
- 1.52 · 1.52±0.1 g/cm3(Predicted)
- storage temp.
- RT
- Löslichkeit
- Soluble in DMSO (up to 15 mg/ml with warming).
- Aggregatzustand
- Tan solid.
- pka
- 2.55 · 2.55±0.20(Predicted)
- Farbe
- Off-white
- Stabilität
- 2 years · Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Chemie und Industrie
Anwendungen
Verwenden1,4-DPCA nis a potent competitive inhibitor of avian prolyl 4-hydroxylase in embryonic chick tendon cells and human foreskin fibroblasts in vitro. It is a promotor of wound healing and tissue regeneration in mice.
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…