CAS 613677-28-4 Benzamide, 2,4,6-trifluoro-N-(6-((1-methyl-4-piperidinyl)carbonyl)-2-pyridinyl)-, hydrochloride (1:1) (HCID 17980336)

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Grundinformationen

CAS: 613677-28-4
Standard-SMILES: CN1CCC(C(=O)c2cccc(NC(=O)c3c(F)cc(F)cc3F)n2)CC1.Cl
InChIKey: YBTPRLDGGGYWIP-UHFFFAOYSA-N
Summenformel: C19H19ClF3N3O2
Durchschnittliche Molmasse: 413,8 g/mol
Monoisotopische Masse: 413,11178919

Namen und Bezeichner

Bevorzugter Name: Benzamide, 2,4,6-trifluoro-N-(6-((1-methyl-4-piperidinyl)carbonyl)-2-pyridinyl)-, hydrochloride (1:1)
IUPAC: 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridinyl]benzamide;hydrochloride
Englischer Name: Benzamide, 2,4,6-trifluoro-N-[6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl]-, hydrochloride (1:1)
Summenformel: C19H19ClF3N3O2
Molmasse: 413.83

Namen und Synonyme

Lasmiditan hydrochloride613677-28-4H7A23C6P5FBenzamide, 2,4,6-trifluoro-N-(6-((1-methyl-4-piperidinyl)carbonyl)-2-pyridinyl)-, hydrochloride (1:1)Benzamide, 2,4,6-trifluoro-N-[6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl]-, hydrochloride (1:1)RefChem:201433Lasmiditan HClLasmiditan (hydrochloride)2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide;hydrochloride2,4,6-Trifluoro-N-(6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl)benzamide hydrochlorideLasmiditan HCl?MFCD30377209

Weitere Namen anzeigen

Lasmiditant HClCOL-144 hydrochloride)LY573144 hydrochlorideLASMIDITAN HCl (COL144 HCl, LY573144 HCl)Lasmiditan hydrochloride (Synonyms: LY 573144 hydrochloride2,4,6-trifluoro-N-[6-(1-methylpiperidine-3-carbonyl)-2-pyridyl]benzamide2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide hydrochloride

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA): 62,3 Å²
H-Brücken-Donoren: 2
H-Brücken-Akzeptoren: 7
Frei drehbare Bindungen: 4
Schwere Atome: 28
Formalladung: 0
Komplexität: 530

Physikochemische Eigenschaften

Schmelzpunkt: 223 · 223-224 °C
storage temp.: -20 °C · Store at -20°C
Löslichkeit: Soluble in DMSO

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P203, P261, P264, P264+P265, P270, P271, P280, P301+P317, P304+P340, P305+P354+P338, P317, P318, P319, P330, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory InformationStatus: Active Update: 28-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/23931

Hazard Classes and CategoriesAcute Tox. 4 (100%)

Sicherheitsdaten

Alarmwort: Warnung
Gefahrenhinweise: Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationEndogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.