Chlormethoxyethan

(chloromethoxy)ethane · Chloromethoxyethane · Ethoxymethyl chloride · Ethyl chloromethyl ether · chloromethoxy-ethane · ClCH2OC2H5 · Ethoxychloromethane · ethoxymethylchloride

https://huagongshe.com/de/chemical/18523

Identifikatoren & physikalische Daten

CAS No.	3188-13-4
Summenformel	C3H7ClO
Durchschnittliche Molmasse	94,54 g/mol
Monoisotopische Masse	94,01854252 g/mol
SMILES	CCOCCl
InChIKey	FCYRSDMGOLYDHL-UHFFFAOYSA-N
PubChem CID	18523
EC No.	221-687-5
DTXSID	DTXSID7062902
Lokaler Name	Chlormethoxyethan

Chemische & physikalische Eigenschaften

XLogP	1,1
Polarare Oberfläche (TPSA)	9,2
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	1
Frei drehbare Bindungen	2
Schwere Atome	5
Formalladung	0
Komplexität	16,4
Stoffklassen	Other Classes -> Halogenated EthersFlammable agents - 3rd degree
SpringerMaterials Properties	Schoenflies notation
Dichte	1.0188 at 15 °C/4 °C1.019 g/mL at 25 °C(lit.)
Siedepunkt	83 °C82 °C(lit.)
Dampfdruck	59.1 [mmHg]
Brechungsindex	Index of Refraction: 1.4040 @ 20 °C/Dn20/D 1.404(lit.)
Physical Description	Chloromethyl ethyl ether appears as a colorless liquid. Slightly denser than water and insoluble in water. May be moderately toxic by ingestion, inhalation or skin absorption. Severely irritates skin, eyes and mucous membranes.[CAMEO]
Schmelzpunkt	-104°C
Flammpunkt	67 °F
Lagerbedingungen	0-6°C
Löslichkeit	Chloroform (Soluble), Ethyl Acetate (Slightly)
Aggregatzustand	Liquid
Wichte	1.019
Farbe	Clear colorless to pale yellow
InChI	InChI=1S/C3H7ClO/c1-2-5-3-4/h2-3H2,1H3
InChIKey	FCYRSDMGOLYDHL-UHFFFAOYSA-N
SMILES	CCOCCl
CAS Datenbank	3188-13-4(CAS DataBase Reference)
NIST chemische Informationen	Ethane, (chloromethoxy)-(3188-13-4)
EPA chemische Informationen	Ethane, (chloromethoxy)- (3188-13-4)

Sicherheit & Vorschriften

GHS-Einstufung	DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P321, P330, P337+P317, P362+P364, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 44 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Regulatorische Informationen	The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
DOT-Kennzeichnung	Flammable Liquid Poison
Brandgefahren	Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Brandpotenzial	A very dangerous fire and explosion hazard when exposed to heat or flame.
Gesundheitsgefahren	Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:· TOXICmay be fatal if inhaled, ingested or absorbed through skin.
Gefahrenübersicht	Inhalation of high concentrations can cause CNS depression[HSDB] A severe skin, eye, and mucous membrane irritant[CAMEO] An eye irritant that causes lacrimationTargets the CNS and liver[MSDSonline]
DOT-Nummer und Handbuch	2354 131
Reaktive Gruppe	Ethers
Reactivity Alerts	Highly Flammable
Reactivity Profile	CHLOROMETHYL ETHYL ETHER tends to form unstable peroxides when exposed to oxygen or air. These products can sometimes be observed as clear crystals deposited on containers or along the surface of the liquid. Forms salts with strong acids and addition complexes with Lewis acids. May react violently with strong oxidizing agents.

Anwendungen & Verwendung

Verwenden

Chloromethyl ethyl ether can be used to prepare:6-Benzyl-1-(ethoxymethyl)-5-iodopyrimidine-2,4(1H,3H)-dione, a key intermediate in the preparation of MKC-442 analog.Acylation catalyst for alcohols named 1,3-bis-[(R)-1-(2-naphthyl)ethyl]imidazoliumchloride by reacting with glyoxal-bis-[(R)-1-(2-naphthyl)ethyl]imine.