| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 20.1% (74 of 369) of reports.WarningH400 (72.6%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]P273, P391, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 369 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|
| Regulatorische Informationen | Chemical: Carbonic acid, zinc salt (1:1)Carbonic acid, zinc salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Carbonic acid, zinc salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 29-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/25398Carbonic acid, zinc salt (1:1): Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
|---|
| Brandgefahren | Behavior in Fire: Could decompose to liberate CO2 (USCG, 1999) |
|---|
| Gesundheitsgefahren | INHALATION OF DUST OR FUMES: Dry throat, cough and chest discomfort. Fever and sweating. SKIN: Astringent. INGESTION: May cause nausea and vomiting. (USCG, 1999) |
|---|
| Gefahrenübersicht | May cause irritation[MSDSonline] See Zinc. |
|---|
| FDA-Anforderungen | Trace minerals added to animal feeds as nutritional dietary supplements are generally recognized as safe when added at levels consistent with good feeding practice. Zinc carbonate is included on this list. |
|---|
| Reaktive Gruppe | Carbonate Salts |
|---|
| Special Reports | Zinc and Health. Current Bibliographies in Medicine 98-3. Public Services Division/National Library of Medicine. 3619 citations, January, 1990-June, 1998. Available from: http://www.nlm.nih.gov/archive/20040831/pubs/cbm/zinc.html as of November 2, 1998.USEPAAmbient Water Quality Criteria Doc: Zinc (1980) EPA 400/5-80-079Ambient Water Quality Criteria Doc: Zinc (1987) EPA 400/5-87-003Arvidson, B. A Review of Axonal Transport of Metals. Toxicology 88: 1-14 (19994) Recent findings regarding axonal transport of metals, including zinc.For more Special Reports (Complete) data for ZINC CARBONATE (6 total), please visit the HSDB record page. |
|---|
| Reactivity Profile | ZINC CARBONATE reacts with acids to generate carbon dioxide and a zinc-containing solution. Dissolves in bases and in solutions of ammonium salts. |
|---|
| Air and Water Reactions | Insoluble in water. |
|---|
| CERCLA-Meldepflichtmengen | Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b). |
|---|
| Clean Water Act Anforderungen | Toxic pollutant designated pursuant to section 307(a)(1) of the Clean Water Act and is subject to effluent limitations. /Zinc & cmpd/Designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. |
|---|
| Hazard Classes and Categories | Aquatic Acute 1 (72.6%) |
|---|
| Erste Hilfe | Call a physican. |
|---|
| Expositionsschutz und Persönliche Schutzausrüstung | 0.1 [mg/m3] (respirable fraction), 2 mg/m3 (inhalable fraction) for Zn inorg. cmpnds[German Research Foundation (DFG)] |
|---|
| Entsorgungsverfahren | SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices. |
|---|
| Minimum Risk Level | Intermediate Oral: 0.3 mg/kg/day (L134)
Chronic Oral: 0.3 mg/kg/day (L134) |
|---|
| Protective Action Criteria (PAC) | 7.7 [mg/m3]84 [mg/m3]510 [mg/m3] |
|---|
| Treatment | Zinc poisoning is treated symptomatically, often by administering fluids such as water or milk, or with gastric lavage. (L49) |
|---|
| Wechselwirkungen | The effects of Eimeria acervulina infection (duodenal coccidiosis) on cadmium toxicity and zinc status in the young chick /were evaluated/. Additions of cadmium (45 mg/kg) were made to diets that contained either 0 or 52 mg/kg supplemental zinc (from zinc carbonate). Growth and efficiency of feed utilization were reduced by dietary cadmium addition while concurrent coccidial infection reduced these parameters further. Addition of cadmium also increased cadmium content of liver and kidney and depressed hemoglobin, hematocrit, and plasma zinc content. Coccidial infection exacerbated tissue cadmium deposition and depressed hematological parameters further. Although dietary zinc addition ameliorated some of the adverse effects of cadmium toxicity, cadium administration tended to enhance tissue zinc deposition. |
|---|
| Gesundheitliche Auswirkungen | Chronic exposure to zinc causes anemia, atazia, lethargy, and decreases the level of good cholesterol in the body. It is also believed to cause pancreatic and reproductive damage. (L49) |
|---|
| Expositionspfade | Inhalation (L49)oral (L49)dermal (L49) |
|---|
| Toxizitätsübersicht | The CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Carbonate...Safe for use in cosmetics, with qualificationsAnaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49) |
|---|
| Signs and Symptoms | Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation. (L49) |
|---|
| Natural Pollution Sources | OCCURS AS THE MINERALS SMITHSONITE AND ZINCSPAR. |
|---|
| Carcinogen Classification | No indication of carcinogenicity to humans (not listed by IARC). |
|---|
| Non-Human Toxicity Excerpts | INTAKES OF ZINC IN FORM OF ... CARBONATE, EQUAL TO 2500 PPM OF THE DIET, ARE COMPLETELY WITHOUT EFFECT ON RATS ... .Female weanling C57BL/6J mice of 21 days of age were fed a diet containing normal (50 ppm) or excess (2000 ppm) levels of zinc administered as zinc carbonate. At about 6 weeks of age, treated females were bred with C57BL/6J males. Offspring were weaned and fed their mothers' diet until sacrifice at 8 weeks of age. Mice exposed to excess zinc during gestation/lactation/postweaning development had reduced plasma copper levels, lower hematocrit values, and reduced body weights, compared to controls. Mice exposed to excess dietary zinc began to lose hair at about 2-4 weeks of age, and at 5 weeks of age, the alopecia was most severe. The skin of treated mice at 5 weeks of age was thinner than that of controls. Hair regrowth began at about 6 weeks of age and the coat of hair had regrown by 8 weeks of age, but was lighter in color than that of control mice.EXCESS ZINC CARBONATE RETARDS GROWTH IN WEANLING RATS, WHICH PRODUCE STILLBORN PUPS WHEN THEY MATURE. ... DIETARY ZINC CARBONATE REDUCED LIVER CYTOCHROME OXIDASE & CATALASE ACTIVITIES WHEN ZINC CONTENT WAS 0.4%.The water insoluble salt, zinc carbonate, was not toxic to fish. Apparently, zinc toxicity to fish is influenced by temperature, pH, and salt solubility.Even when they were fed zinc carbonate at a dietary level of 7000 ppm of zinc (350 mg/kg/day), young rats survived, although they developed marked anemia in 4 weeks and grew poorly. A dietary level of 10,000 ppm killed up to 75% of rats in 3-5 weeks. |
|---|
| Landesrichtlinien für Trinkwasser | (AZ) ARIZONA 5000 ug/l /Zinc/(MN) MINNESOTA 2000 ug/l /Zinc/ |
|---|
| Bundesrichtlinien für Trinkwasser | EPA 5000 ug/l /Zinc/EPA 2000 ug/l /Zinc, Lifetime health advisory/ |
|---|
