HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chlor-6-(1-piperazinyl)pyrazinmonohydrochlorid
NSC 31732 · MK-212 (monohydrochloride) · MK-212 hydrochloride >=98% (HPLC) · MK 212 hydrochloride, 5-HT2C receptor agonist · 2-chloro-6-(piperazin-1-yl)pyrazine hydrochloride · 2-Chloro-6-(1-piperazinyl)-pyrazine hydrochloride · 2-chloro-6-(1-piperazinyl)pyrazine monohydrochloride · 5-HT Receptor,5-hydroxytryptamine Receptor,Inhibitor,Serotonin Receptor,MK 212 hydrochloride,MK-212 monohydrochloride,inhibit,CPP monohydrochloride
Identifikatoren & physikalische Daten
| CAS No. | 61655-58-1 |
|---|---|
| Summenformel | C8H12Cl2N4 |
| Durchschnittliche Molmasse | 235,11 g/mol |
| Monoisotopische Masse | 234,04390174 g/mol |
| SMILES | Cl.Clc1cncc(N2CCNCC2)n1 |
| InChIKey | PFIZGLUIYAZQFU-UHFFFAOYSA-N |
| PubChem CID | 198421 |
| ChEMBL | CHEMBL3250751 |
| EC No. | 262-883-0 |
| DTXSID | DTXSID60210668 |
| Lokaler Name | 2-Chlor-6-(1-piperazinyl)pyrazinmonohydrochlorid |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 41,1 |
|---|---|
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 14 |
| Formalladung | 0 |
| Komplexität | 160 |
| Lagerbedingungen | Inert atmosphere,2-8°C |
| Löslichkeit | DMSO: ≥20mg/mLSoluble to 50 mM in water with gentle warming |
| Aggregatzustand | powder |
| Farbe | white to off-white |
| InChI | 1S/C8H11ClN4.ClH/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13/h5-6,10H,1-4H21H |
| InChIKey | PFIZGLUIYAZQFU-UHFFFAOYSA-N |
| SMILES | Cl.Clc1cncc(n1)N2CCNCC2 |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.WarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
|---|---|
| Hazard Classes and Categories | Acute Tox. 3 (100%)Acute Tox. 4 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | UN 2811 6.1 / PGIII |
| R-Sätze (R) | 25 |
| Gefahrensymbole | T |
| Sicherheitshinweise (S) | 45 |
| Lagerklasse | 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects |
| Gefahrenklasse | Acute Tox. 3 Oral |
Anwendungen & Verwendung
Verwenden
MK 212 Hydrochloride is a 5-HT2C agonist that may possess antipsychotic activity; however, mainly functions as an anti-stress treatment when ingested.