HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
kopsine
kopsine · 3-Hydroxy-22-oxokopsan-1-carboxylic acid methyl ester · 6H,13aH-3a,5a-Ethano-5,11-methano-1H-indolizino[8,1-cd]carbazole-6-carboxylic acid, 2,3,4,5,11,12-hexahydro-5-hydroxy-14-oxo-, methyl ester, (3aR,5S,5aS,10bR,11R,13aS)- (9CI)
Identifikatoren & physikalische Daten
| CAS No. | 559-48-8 |
|---|---|
| Summenformel | C22H24N2O4 |
| Durchschnittliche Molmasse | 380,44 g/mol |
| SMILES | COC(=O)N1c2ccccc2[C@@]23[C@@H]4CN5CCC[C@]6(CC[C@]12[C@@](O)(C6)C4=O)[C@H]53 |
| InChIKey | YROYAGSZNDUMIF-QAZQQZDDSA-N |
| PubChem CID | 20054949 |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 220°C (dec.). |
|---|
Anwendungen & Verwendung
Beschreibung
The major constituent of Kopsia !ruticosa, this base has [α]D - 17.5° (c 2.15, CHC13). It forms a series of crystalline salts and derivatives, e.g. the aurichloride, m.p. 203-5°C (dec.); perchlorate, m.p. 284°C (dec.); picrate, m.p. 230°C (dec.) and methiodide, m.p. 200°C (dec.). It may be reduced to the dihydro derivative which has m.p. 218°C. When fused with NaOH the alkaloid furnishes 2- methylindole and 2-indole-2-carboxylic acid.