HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Norarecoline Hydrochloride
Guvacoline hydrochloride · Norarecoline hydrochloride · Guvacoline HCl · methyl 1,2,3,6-tetrahydropyridine-5-carboxylate,hydrochloride · Methyl 1,2,5,6-Tetrahydropyridine-3-carboxylate Hydrochloride · mAChR,Inhibitor,Guvacoline hydrochloride,Guvacoline,inhibit,Muscarinic acetylcholine receptor
Identifikatoren & physikalische Daten
| CAS No. | 6197-39-3 |
|---|---|
| Summenformel | C7H12ClNO2 |
| Durchschnittliche Molmasse | 177,63 g/mol |
| Monoisotopische Masse | 177,0556563 g/mol |
| SMILES | COC(=O)C1=CCCNC1.Cl |
| InChIKey | ZWALOEQHJRUTKM-UHFFFAOYSA-N |
| PubChem CID | 201540 |
| EC No. | 854-692-1 |
| DTXSID | DTXSID10210996 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 38,3 |
|---|---|
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 11 |
| Formalladung | 0 |
| Komplexität | 163 |
| Schmelzpunkt | 121-122 °C |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| Löslichkeit | DMSO |
| Aggregatzustand | Solid |
| Farbe | Light yellow |
| Hauptanwendungen | food and beveragespharmaceutical |
| InChI | InChI=1S/C7H11NO2.ClH/c1-10-7(9)6-3-2-4-8-5-6/h3,8H,2,4-5H2,1H3 |
| InChIKey | ZWALOEQHJRUTKM-UHFFFAOYSA-N |
| SMILES | C1NCCC=C1C(OC)=O.[H]Cl |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | WGK 3 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Acute Tox. 4 Oral |
Anwendungen & Verwendung
Verwenden
Guvacoline Hydrochloride is an intermediate in the synthesis of N-Nitrosoguvacoline (N527625), one of the N-nitrosation products of arecoline. It is the only one N-nitrosamine found in Taiwanese betel quid chewing saliva. It is used as a standard for the determination of Nitrosamine in tobacco smoke.