HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethacridin
ACRINOL · Ethacridine · RIVANOL · Etakridin · Ethacrindine · 2-Ethoxy-6,9-acridinediamine · 7-Ethoxy-3,9-acridinediamine · 6,9-DIAMINO-2-ETHOXYACRIDINE
Identifikatoren & physikalische Daten
| CAS No. | 442-16-0 |
|---|---|
| Summenformel | C15H15N3O |
| Durchschnittliche Molmasse | 253,3 g/mol |
| Monoisotopische Masse | 253,12151211 g/mol |
| SMILES | CCOc1ccc2nc3cc(N)ccc3c(N)c2c1 |
| InChIKey | CIKWKGFPFXJVGW-UHFFFAOYSA-N |
| PubChem CID | 2017 |
| ChEMBL | CHEMBL94007 |
| ChEBI | CHEBI:135032 |
| EC No. | 207-130-9 |
| DTXSID | DTXSID2048402 |
| Lokaler Name | Ethacridin |
Chemische & physikalische Eigenschaften
| XLogP | 2,5 |
|---|---|
| Polarare Oberfläche (TPSA) | 74,2 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 19 |
| Formalladung | 0 |
| Komplexität | 312 |
| Arzneimittel | PharmaceuticalsPharmaceuticals -> Antibiotics |
| Schmelzpunkt | 226° |
| Siedepunkt | 396.5°C (rough estimate) |
| Dichte | 1.0966 (rough estimate) |
| Brechungsindex | 1.5700 (estimate) |
| Lagerbedingungen | 2-8°C |
| pKa (Säurekonstante) | 11.22±0.10(Predicted) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 4.9% (2 of 41) of reports.WarningH302 (95.1%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 41 reports by companies from 2 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | REACH registered substance: Ethacridine (EC: 207-130-9) |
| Weitere Sicherheitsinformationen | IMAP assessments - 3,9-Acridinediamine, 7-ethoxy-: Human health tier I assessment |
| Hazard Classes and Categories | Acute Tox. 4 (95.1%) |
| Alarmwort | Warnung |
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302 |
Anwendungen & Verwendung
Verwenden
7-ethoxyacridine-3,9-diamine is used in biological studies for cancer regression by inducing a regeneration-like response by activating expression and/or function of YAP and/or TAZ.