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5051-22-9CC(C)NC[C@@H](O)COc1cccc2ccccc12AQHHHDLHHXJYJD-CQSZACIVSA-N5051-22-9DTXSID3045304CHEMBL275742CHEBI:8736HistoryScottish scientist James W. Black developed propranolol in the 1960s. It was the first beta-blocker effectively used in the treatment of coronary artery disease and hypertension.Propranolol was patented in 1962 and approved for medical use in 1964. It is on the World Health Organization's List of Essential Medicines. In 2023, it was the 69th most commonly prescribed medication in the United States, with more than 9 million prescriptions.
VerwendenPropranolol has been studied most carefully in experiments and in clinics. It is used for ventricular tachycardia, arrhythmia caused by digitalis drug overdose, or as a result of thyrotoxosis or excess catecholamine activity. Despite the fact that there are a number of β-adrenoblockers, propranolol is considered the first choice of drugs although other blockers of calcium blockers can be just as effective.
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