Aminoguanidin

Aminoguanidine

HCID 2146CAS 79-17-4

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Grundinformationen

Standard-SMILES: NN=C(N)N
InChIKey: HAMNKKUPIHEESI-UHFFFAOYSA-N
Summenformel: CH6N4
Durchschnittliche Molmasse: 74,09 g/mol
Monoisotopische Masse: 74,05924619

Überblick

Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.

Namen und Bezeichner

Bevorzugter Name: Aminoguanidine
IUPAC: 2-aminoguanidine
Lokaler Name: Aminoguanidin
Englischer Name: Aminoguanidine
Summenformel: CH6N4
Molmasse: 74.09

Namen und Synonyme

aminoguanidinePimagedineHydrazinecarboximidamide79-17-4Guanyl hydrazineMonoaminoguanidineAminate baseImino semicarbazide1-aminoguanidinepimagedinaSCQ4EZQ113DTXSID5040964

Weitere Namen anzeigen

Aids030897Aids-030897N-AminoguanidineAminoguanidine (ag)Ribavirin Impurity S

CHEBI:40618pimagedinumRefChem:112042DTXCID3020964201-183-12-aminoguanidinePimagedine [INN]GUANIDINE, AMINO-

Datenbank-Bezeichner

CAS: 79-17-4
PubChem CID: 2146
DTXSID: DTXSID5040964
ChEMBL: CHEMBL225304
ChEBI: CHEBI:40618
UNII: SCQ4EZQ113
EC Number: 201-183-1
Nikkaji: J5.508E

Eigenschaften

Berechnete Struktureigenschaften

XLogP: -1,5
Polarare Oberfläche (TPSA): 90,4 Å²
H-Brücken-Donoren: 3
H-Brücken-Akzeptoren: 2
Frei drehbare Bindungen: 0
Schwere Atome: 5
Formalladung: 0
Komplexität: 41,6

Experimentelle und physikochemische Eigenschaften

DrugsPharmaceuticals -> Listed in ZINC15

Physikochemische Eigenschaften

Schmelzpunkt: 182 · 182-185 °C (decomp)
Siedepunkt: 159.5 · 159.5±23.0 °C(Predicted)
Dichte: 1.72 · 1.72±0.1 g/cm3(Predicted)
Brechungsindex: 1.666 · 1.6660 (estimate)
pka: 11.08 · 11.08±0.70(Predicted)

Chemie und Industrie

Pharmakologische Informationen

Mechanism of ActionPimagedine reportedly inhibits the formation of glycosylated proteins (advanced glycosylation end-products) and has other actions including inhibition of aldose reductase.

MeSH Pharmacological ClassificationCompounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Anwendungen

VerwendenInhibitor (advanced glycosylation end-product formation).

Vor- und nachgelagerte Produkte

Vorgelagerte Rohstoffe

Nachgelagerte Produkte

2-(2,3-Dichlorophenyl)-2-guanidinyliminoacetonitrile Cyclohexanon Pentan-3-on Cyclopentanon 3,3-Dimethylbutanon 2,6-Dichlorbenzaldehyd Butanon

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Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.