Grundinformationen
- CAS
5749-67-7- Standard-SMILES
CC(=O)Oc1ccccc1C(=O)[O-].CC(=O)Oc1ccccc1C(=O)[O-].NC(N)=O.[Ca+2]- InChIKey
VYMUGTALCSPLDM-UHFFFAOYSA-L- Summenformel
- C19H18CaN2O9
- Durchschnittliche Molmasse
- 458,4 g/mol
- Monoisotopische Masse
- 458,063821
Namen und Bezeichner
- Bevorzugter Name
- Carbaspirin Calcium
- IUPAC
- calcium;bis(2-acetyloxybenzoate);urea
- Lokaler Name
- Carbasalatcalcium
- Englischer Name
- Carbasalate calcium
- Summenformel
- C10H14CaN2O5
- Molmasse
- 282.31
Namen und Synonyme
CARBASPIRIN CALCIUMCalcium carbaspirinN667F17JP1DTXSID90206099carbosalate calciumCalcium carbasalateCalcium acetylsalicylic carbamidateRefChem:574158DTXCID40128590calcium urea bis(2-(acetyloxy)benzoate)227-273-0Carbasalate calcium
Weitere Namen anzeigen
OmeginAlcacylRheominSolupsanCarbaspirinComplex with ureaarbasalate calciumCarbasalate CaliumCarbasalac Calcium
5749-67-7Carbasalate calciqueCarbasalato calcicoCarbaspirin calcium [USAN]Carbasalate calcium [INN]calcium;2-acetyloxybenzoate;ureaCarbasalate calcium (INN)Carbaspirin calcium (USAN)
Datenbank-Bezeichner
- CAS
5749-67-7、93803-83-9- PubChem CID
- 21975
- DTXSID
DTXSID90206099
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 202 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 9
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 31
- Formalladung
- 0
- Komplexität
- 235
Physikochemische Eigenschaften
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- Freely soluble in water and in dimethylformamide, practically insoluble in acetone and in anhydrous methanol.
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- InChI
- InChI=1S/C9H8O4.CH4N2O.Ca.2H/c1-6(10)13-8-5-3-2-4-7(8)9(11)12;2-1(3)4;;;/h2-5H,1H3,(H,11,12);(H4,2,3,4);;;
- InChIKey
- BMMIBWSFPSYDEH-UHFFFAOYSA-N
- SMILES
- C(=O)(N)N.C(C1C=CC=CC=1OC(=O)C)(=O)O.[Ca]
- CAS Datenbank
- 5749 · 5749-67-7
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]；H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Gefahrenhinweise
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Sicherheitsdaten
- Alarmwort
- Warnung
- Gefahrenhinweise
- Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302
Chemie und Industrie
Pharmakologische Informationen
ATC Code
N - Nervous system；N02 - Analgesics；N02B - Other analgesics and antipyretics；N02BA - Salicylic acid and derivatives；N02BA15 - Carbasalate calcium
B - Blood and blood forming organs；B01 - Antithrombotic agents；B01A - Antithrombotic agents；B01AC - Platelet aggregation inhibitors excl. heparin；B01AC08 - Carbasalate calcium
QN - Nervous system；QN02 - Analgesics；QN02B - Other analgesics and antipyretics；QN02BA - Salicylic acid and derivatives；QN02BA15 - Carbasalate calcium
QB - Blood and blood forming organs；QB01 - Antithrombotic agents；QB01A - Antithrombotic agents；QB01AC - Platelet aggregation inhibitors, excl. heparin；QB01AC08 - Carbasalate calcium
MeSH Pharmacological Classification
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Anwendungen
BeschreibungCarbasalate calcium is a calcium-urea chelate of aspirin that has analgesic, anti-inflammatory, and antipyretic effects. It reduces carrageenan-induced paw edema in rats.
VerwendenCarbasalate Calcium is an analgesic, antipyretic, and anti-inflammatory drug.
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