HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Brucin
Polyamide resin · Nylon fibers · Polyamide fibers · Polyamide multipolymer · Polyamide curing agent （651） · Polyamide resin,low molecular weight 651 · Polyamide · Polyamid eP
Identifikatoren & physikalische Daten
| CAS No. | 1358802-83-1 |
|---|---|
| Summenformel | C23H26N2O4 |
| Durchschnittliche Molmasse | 394,5 g/mol |
| Monoisotopische Masse | 394,18925731 g/mol |
| SMILES | COc1cc2c(cc1OC)C13CCN4CC5=CCOC6CC(=O)N2C1C6C5CC43 |
| InChIKey | RRKTZKIUPZVBMF-UHFFFAOYSA-N |
| PubChem CID | 220520 |
| EC No. | 805-352-6 |
| DTXSID | DTXSID10859344 |
Chemische & physikalische Eigenschaften
| XLogP | 1 |
|---|---|
| Polarare Oberfläche (TPSA) | 51,2 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 29 |
| Formalladung | 0 |
| Komplexität | 785 |
| Food Contact Substances | FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR |
| Dielektrizitätskonstante | 2.5(Ambient) |
| EPA chemische Informationen | Polyamide fibers (63428-84-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 100% (6 of 6) of all reports.Not ClassifiedAggregated GHS information provided per 6 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Not Classified |
| Treatment | Treatment of brucine poisoning involves an oral application of an activated charcoal infusion to absorb any poison within the digestive tract that has not yet been absorbed into the blood. Anticonvulsants such as phenobarbital or diazepam are administered to control convulsions, along with muscle relaxants such as dantrolene to combat muscle rigidity. (L1228) |
| Gesundheitliche Auswirkungen | Death may result from asphyxia or sheer exhaustion. (L1227) |
| Expositionspfade | Oral (ingestion) (L1817)dermal (L1817) |
| Toxizitätsübersicht | Brucine acts as an antagonist at the inhibitory or strychnine-sensitive glycine receptor, a ligand-gated chloride channel in the spinal cord and the brain. (L1230) |
| Signs and Symptoms | Brucine causes muscular convulsions of increasing intensity and frequency and eventually death through asphyxia or sheer exhaustion. (L1227) |
| Carcinogen Classification | No indication of carcinogenicity to humans (not listed by IARC). |
| Toxicity Data | LD50: 4 mg/kg (Oral, Rat) (T14) LD50: 91 mg/kg (Intraperitoneal, Rat) (T14) LD50: 60 mg/kg (Subcutaneous, Rat) (T14) |
Anwendungen & Verwendung
Verwenden
Polyamide (cas# 63428-84-2) is synthetic polymer of a type made by the linkage of an amino group of one molecule and a carboxylic acid group of another, including many synthetic fibers such as nylon. A polyamide is a macromolecule with repeating units linked by amide bonds.