HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Iodopyridine
JACS-5029-67-4 · 2-lodopyridine · 2-IODOPYRIDINE · 2-Pyridyl iodide · Pyridine, 2-iodo- · 2-Iodine Pyridine · 2-Iodopyridine 98% · 2-Iodopyridine 2-IODOPYRIDINE, 95+%
Identifikatoren & physikalische Daten
| CAS No. | 5029-67-4 |
|---|---|
| Summenformel | C5H4IN |
| Durchschnittliche Molmasse | 205 g/mol |
| Monoisotopische Masse | 204,93884713 g/mol |
| SMILES | Ic1ccccn1 |
| InChIKey | CCZWSTFVHJPCEM-UHFFFAOYSA-N |
| PubChem CID | 221126 |
| ChEMBL | CHEMBL3274303 |
| EC No. | 610-520-5 |
| DTXSID | DTXSID60903821 |
Chemische & physikalische Eigenschaften
| XLogP | 1,4 |
|---|---|
| Polarare Oberfläche (TPSA) | 12,9 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 7 |
| Formalladung | 0 |
| Komplexität | 56 |
| SpringerMaterials Properties | Molecular structure |
| Schmelzpunkt | 118-120℃ |
| Siedepunkt | 52 °C (lit.) |
| Dichte | 1.928 g/mL at 25 °C (lit.) |
| Brechungsindex | n20/D 1.6320(lit.) |
| Lagerbedingungen | Keep in dark place,Sealed in dry,Room Temperature |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | pK1:1.82(+1) (25°C) |
| Farbe | Pale yellow |
| Löslichkeit | Slightly soluble in water. |
| InChI | InChI=1S/C5H4IN/c6-5-3-1-2-4-7-5/h1-4H |
| InChIKey | CCZWSTFVHJPCEM-UHFFFAOYSA-N |
| SMILES | C1(I)=NC=CC=C1 |
| CAS Datenbank | 5029-67-4(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 42 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29333990 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| hazard_note | Irritant |
| Sicherheitshinweise (S) | 26-36 |
| Lagerklasse | 10 - Combustible liquids |
| Gefahrenklasse | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Verwenden
2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.