3-β-Hydroxy-5-α-androstan-17-on
TRANS-ANDROSTERONE · ISOANDROSTERONE · EpiA · 5ALPHA-ANDROSTAN-3BETA-OL-17-ONE · 3-Hydroxyandrostan-17-one · Androstan-17-one, 3-hydroxy-, (3b,5a)- · NSC 93996 · epirosterone
Identifikatoren & physikalische Daten
| CAS No. | 481-29-8 |
|---|---|
| Summenformel | C19H30O2 |
| Durchschnittliche Molmasse | 290,4 g/mol |
| Monoisotopische Masse | 290,2245802 g/mol |
| SMILES | CC12CCC3C(CCC4CC(O)CCC43C)C1CCC2=O |
| InChIKey | QGXBDMJGAMFCBF-UHFFFAOYSA-N |
| PubChem CID | 225 |
| ChEMBL | CHEMBL4744187 |
| Lokaler Name | 3-β-Hydroxy-5-α-androstan-17-on |
Chemische & physikalische Eigenschaften
| XLogP | 3,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 37,3 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 21 |
| Formalladung | 0 |
| Komplexität | 458 |
| Schmelzpunkt | 172-174 °C |
| Siedepunkt | 372.52°C (rough estimate) |
| Dichte | 1.0320 (rough estimate) |
| Brechungsindex | 1.4709 (estimate) |
| Lagerbedingungen | Refrigerator |
| Löslichkeit | insoluble in H2O≥12.35 mg/mL in EtOH≥28.27 mg/mL in DMSOpractically insoluble |
| Aggregatzustand | solid |
| pKa (Säurekonstante) | 15.14±0.60(Predicted) |
| Farbe | White to off-white |
| Biologische Quelle | synthetic (organic) |
| Merck | 3609 |
| BRN | 1884007 |
| InChI | 1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-16,20H,3-11H2,1-2H3/t12-,13-,14-,15-,16-,18-,19-/m0/s1 |
| InChIKey | QGXBDMJGAMFCBF-LUJOEAJASA-N |
| SMILES | [H][C@@]12CC[C@@]3([H])[C@]4([H])CCC(=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@H](O)C2 |
| LogP (Verteilungskoeffizient) | 3.751 |
| CAS Datenbank | 481-29-8(CAS DataBase Reference) |
| NIST chemische Informationen | 3Beta-hydroxy-5alpha-androstan-17-one(481-29-8) |
Sicherheit & Vorschriften
| F | 21 |
|---|---|
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29144000 |
| Sicherheitshinweise (S) | 22-24/25 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Repr. 2 |
Anwendungen & Verwendung
Beschreibung
Epiandrosterone is a steroid hormone with weak androgenic activity, derived from 5 α-androstane. It is a dehydroepiandrosterone metabolite and an androgen. It is a precursor of testosterone and estradiol with hypolipidemic and anabolic activities.
Verwenden
Epiandrosterone is used for weight loss, to improve athletic performance, to reduce sexual problems, and for many other uses, but there is no good scientific evidence to support its use. Epiandrosterone might also be unsafe.Epiandrosterone is a steroid hormone that is present in normal human urine as a minor constituent , it is a less active 3β-isomer of the androgen Androsterone (A635535). Controlled Substance.