HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
D-Glutaminsure
D-GLUTAMIC ACID · D-GLU · D-GLUCURONOLACTONE · H-D-GLU-OH · D-Glutamate · d-glutamic · (R)-GLUTAMIC ACID · (2R)-2-aminopentanedioic acid
Identifikatoren & physikalische Daten
| CAS No. | 6893-26-1 |
|---|---|
| Summenformel | C5H9NO4 |
| Durchschnittliche Molmasse | 147,13 g/mol |
| Monoisotopische Masse | 147,05315777 g/mol |
| SMILES | N[C@H](CCC(=O)O)C(=O)O |
| InChIKey | WHUUTDBJXJRKMK-GSVOUGTGSA-N |
| PubChem CID | 23327 |
| ChEMBL | CHEMBL76232 |
| ChEBI | CHEBI:15966 |
| EC No. | 230-000-8 |
| DTXSID | DTXSID1048675 |
| Lokaler Name | D-Glutaminsure |
Chemische & physikalische Eigenschaften
| XLogP | -3,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 101 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 4 |
| Schwere Atome | 10 |
| Formalladung | 0 |
| Komplexität | 145 |
| Stoffklassen | Biological Agents -> Amino Acids and Derivatives |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Löslichkeit | 8.88 mg/mL at 25 °CWater (Slightly)7 g/L (20 ºC) |
| Schmelzpunkt | 201 °C200-202 °C (subl.)(lit.) |
| Physical Description | Shinny solid[Merck Index] White crystalline powder[Alfa Aesar MSDS] |
| Siedepunkt | 267.21°C (rough estimate) |
| Dichte | 1.5380 |
| Brechungsindex | 1.4210 (estimate) |
| Lagerbedingungen | Keep in dark place,Sealed in dry,Room Temperature |
| pKa (Säurekonstante) | pK1:2.162(＋1)pK2:4.272(0)pK3:9.358(－1) (25°C) |
| Aggregatzustand | Powder |
| Farbe | White to off-white |
| Merck | 14,4469 |
| BRN | 1723800 |
| InChI | 1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1 |
| InChIKey | WHUUTDBJXJRKMK-GSVOUGTGSA-N |
| SMILES | N[C@H](CCC(O)=O)C(O)=O |
| LogP (Verteilungskoeffizient) | -0.969 (est) |
| CAS Datenbank | 6893-26-1(CAS DataBase Reference) |
| NIST chemische Informationen | D-Glutamic acid(6893-26-1) |
| EPA chemische Informationen | D-Glutamic acid (6893-26-1) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 83.3% (5 of 6) of all reports.WarningH315 (16.7%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 6 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | D-Glutamic acid: Does not have an individual approval but may be used under an appropriate group standard |
| Gefahrenübersicht | May cause irritation[Alfa Aesar MSDS] |
| Hazard Classes and Categories | Skin Irrit. 2 (16.7%) |
| F | 10 |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29224200 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 24/25-36-26 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
D-Glutamic Acid is the unnatural (R)-enantiomer of Glutamic Acid, a non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. Glutamic Acid is also a key molecule in cellular metabolism.