Prx-07034
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Grundinformationen
- CAS
903580-39-2- Standard-SMILES
COc1cc(Cl)cc(C(C)Nc2cc(N3CCNCC3)ccc2S(C)(=O)=O)c1OC.Cl- InChIKey
PILCQJJJAFRKHO-UHFFFAOYSA-N- Summenformel
- C21H29Cl2N3O4S
- Durchschnittliche Molmasse
- 490,4 g/mol
- Monoisotopische Masse
- 489,12558277
Namen und Bezeichner
- Bevorzugter Name
- Prx-07034
- IUPAC
- N-[1-(5-chloro-2,3-dimethoxyphenyl)ethyl]-2-methylsulfonyl-5-piperazin-1-ylaniline;hydrochloride
Namen und Synonyme
903580-39-2PRX-07034PRX-07034 hydrochloride336H22ETCGUNII-336H22ETCGBenzenemethanamine, 5-chloro-2,3-dimethoxy-alpha-methyl-N-(2-(methylsulfonyl)-5-(1-piperazinyl)phenyl)-, hydrochloride (1:1)N-[1-(5-chloro-2,3-dimethoxyphenyl)ethyl]-2-methanesulfonyl-5-(piperazin-1-yl)aniline hydrochlorideBENZENEMETHANAMINE, 5-CHLORO-2,3-DIMETHOXY-.ALPHA.-METHYL-N-(2-(METHYLSULFONYL)-5-(1-PIPERAZINYL)PHENYL)-, HYDROCHLORIDE (1:1)N-(1-(5-chloro-2,3-dimethoxyphenyl)ethyl)-2-methanesulfonyl-5-(piperazin-1-yl)aniline hydrochlorideRefChem:176772N-(1-(5-Chloro-2,3-dimethoxyphenyl)ethyl)-2-(methylsulfonyl)-5-(piperazin-1-yl)aniline hydrochloridePRX 07034
Weitere Namen anzeigen
PRX-07034 (hydrochloride)Benzenemethanamine, 5-chloro-2,3-dimethoxy-alpha-methyl-N-[2-(methylsulfonyl)-5-(1-piperazinyl)phenyl]-, monohydrochlorideBenzenemethanamine, 5-chloro-2,3-dimethoxy-|A-methyl-N-[2-(methylsulfonyl)-5-(1-piperazinyl)phenyl]-, monohydrochlorideN-[1-(5-Chloro-2,3-dimethoxyphenyl)ethyl]-2-methylsulfonyl-5-piperazin-1-ylaniline hydrochlorideN-[1-(5-chloro-2,3-dimethoxyphenyl)ethyl]-2-methylsulfonyl-5-piperazin-1-ylaniline;hydrochlorideMFCD25976674C21H29Cl2N3O4SSCHEMBL475692
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- Polarare Oberfläche (TPSA)
- 88,3 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 7
- Frei drehbare Bindungen
- 7
- Schwere Atome
- 31
- Formalladung
- 0
- Komplexität
- 641
Chemie und Industrie
Pharmakologische Informationen
Mechanism of Action
PRX-07034 is a novel, highly selective, small-molecule antagonist of a specific G-protein coupled receptor (GPCR) known as 5-HT6 being developed for the treatment of obesity, Alzheimer's disease and cognitive impairment associated with schizophrenia. PRX-07034 has also been shown to enhance cognitive function in preclinical animal models of memory impairment through a dual mechanism of action.It has an effect on both the acetylcholine and glutamate neurotransmitter systems in the brain, which makes it a potentially complementary therapy to cholinesterase inhibitors, a class of drugs approved for the treatment of Alzheimer's disease.
Anbieter22 Anbieter
Hangzhou IKSChem Technology Co., Limited13625816949 · [email protected]
南京腾怡生物科技有限公司17714337195 · [email protected]
上海楼岚生物科技有限公司021-52996696，15000506266 15000506266
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
上海鹤成医药科技有限公司13564747822 · [email protected]
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