Monosodium Citrate (HCID 23666341)

Namen und Bezeichner

Bevorzugter Name: Monosodium Citrate
IUPAC: sodium 3-carboxy-3,5-dihydroxy-5-oxopentanoate
Lokaler Name: Natriumdihydrogencitrat
Englischer Name: Sodium dihydrogen citrate
Summenformel: C6H9NaO7
Molmasse: 216.12

Namen und Synonyme

18996-35-5Monosodium citrateSodium citrate monobasicSodium dihydrogen citrate1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monosodium salt1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:1)DTXSID8087290468538UP9SEE 331IRefChem:159615DTXCID707348242-734-6

Weitere Namen anzeigen

DIHYDROGEN CITRATEcitrofluylcitricacid,sodiumsaltNatriumdihydrogencitratmonosodiumdihydrogencitrate

sodium 3,4-dicarboxy-3-hydroxybutanoateCitric acid monosodium saltC6H7NaO7Monosodium Citrate Anhydroussodium;3-carboxy-3,5-dihydroxy-5-oxopentanoateSodium dihydrogencitratemono sodium citrateMFCD00013067

Datenbank-Bezeichner

CAS: 18996-35-5
PubChem CID: 23666341
DTXSID: DTXSID80872904
EC Number: 242-734-6
Nikkaji: J1.390.397B

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA): 135 Å²
H-Brücken-Donoren: 3
H-Brücken-Akzeptoren: 7
Frei drehbare Bindungen: 5
Schwere Atome: 14
Formalladung: 0
Komplexität: 251

Experimentelle und physikochemische Eigenschaften

Chemical ClassesMetals -> Organic Acids, Metal Salts

CosmeticsCosmetic ingredients (Monosodium Citrate) -> CIR (Cosmetic Ingredient Review)

pHBetween 3,5 and 3,8 (1 % aqueous solution)

Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

Physical Description · 3 Einträge

Liquid; Liquid; Other Solid; Dry Powder

Crystalline white powder or colourless crystals

White odorless solid; [JECFA] White crystalline powder; [Alfa Aesar MSDS]

Physikochemische Eigenschaften

Schmelzpunkt: 212 °C · 212 °C(lit.)
storage temp.: Inert atmosphere,Room Temperature
Löslichkeit: 2 O: · H2O: 0.25 M at 20 °C, clear, colorless
Aggregatzustand: Crystalline Powder
Farbe: White
Geruch (Odor): Odorless
PH: 4.07 · 4.07(1 mM solution);3.87(10 mM solution);3.71(100 mM solution);3.48(1000 mM solution)
Wasserlöslichkeit: Soluble in water. Insoluble in ethanol.
BRN: 3920246 · 3920246
Kosmetik-Inhaltsstoffe Funktionen: BUFFERING
InChI: InChI=1S/C6H8O7.Na.H/c7-3(8)1-6(13,5(11)12)2-4(9)10;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;
InChIKey: JKYDHHIKDADVTE-UHFFFAOYSA-N
SMILES: C(O)(C(=O)O)(CC(=O)O)CC(=O)O.[NaH]
CAS Datenbank: 18996 · 18996-35-5(CAS DataBase Reference)
EPA chemische Informationen: 1 · 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monosodium salt (18996-35-5)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 3 Einträge

This chemical does not meet GHS hazard criteria for 98.7% (226 of 229) of all reports.

Not Classified

Aggregated GHS information provided per 229 reports by companies from 4 notifications to the ECHA C&L Inventory.

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monosodium salt

1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 31-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14189

Monosodium citrate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monosodium salt: Human health tier I assessment

Hazards SummaryCauses convulsions in intraperitoneal lethal-dose studies of mice and rats; [RTECS] Acceptable daily intake (ADI) as food additive not limited; [JECFA] May cause irritation; [Alfa Aesar MSDS] See Citric acid.

EPA Safer ChemicalChemical: Sodium dihydrogen citrate

Hazard Classes and CategoriesNot Classified

Sicherheit und Schutzausrüstung

Protective Action Criteria (PAC) · 3 Einträge

9.0 [mg/m3]

99 [mg/m3]

590 [mg/m3]

Toxikologische Informationen

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

Sicherheitsdaten

F: 3
wgk: 1
tsca: TSCA listed
hs_code: 29181500
RTECS-Nr.: GE7950000
risk_code: 36
hazard_code: Xi
safety_code: 22-24/25
Speicherklasse: 11 - Combustible Solids

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 3 Einträge

Agents that prevent BLOOD CLOTTING.

A chemical system that functions to control the levels of specific ions in solution. When the level of hydrogen ion in solution is controlled the system is called a pH buffer.

Substances capable of inhibiting, retarding or arresting the process of fermentation, acidification or other deterioration of foods.

Verwendung und Herstellung

Uses · 2 Einträge

CIR ingredient: Monosodium Citrate

Used as a buffering agent and sequestrant for food; [JECFA] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]

U.S. Production2023: 850,000 - <1,000,000 lb

Consumer UsesPropellants, non-motive (blowing agents)

Industry UsesPropellants, non-motive (blowing agents)

Household ProductsInformation on 47 consumer products that contain Sodium dihydrogen citrate in the following categories is provided:

Use Classification · 6 Einträge

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Food additives

Food Additives -> ACIDITY_REGULATOR; SEQUESTRANT -> JECFA Functional Classes

Anwendungen · 2 Einträge

BeschreibungMono sodium citrate, or sodium dihydrogen citrate, is an acid salt with the chemical formula NaH2C6H5O7, or C3H4OH(COOH)2COONa. Since it has two remaining open spots on the citrate anion, it is used as a relatively strong sequestrant. It is used to prevent platelet clumping in blood samples. It is one of the 3 citric acid salts.

VerwendenSodium dihydrogen citrate acts as a buffering agent and sequestrant. It is also employed as a reductant and stabilizer in the preparation of b>Fe3O4 platinum core/shell particles. Further, it is used in electrochemical reduction of proton at carbon fiber electrode in the presence and absence of platinum nanoparticles. In addition to this, it plays a useful role in characterization of carbon-based electrode materials as cathode in half-cell configuration.

Darstellung

synthetischeMonosodium citrate can be prepared by the direct reaction of sodium carbonate or bicarbonate with citric acid: NaHCO3(s) + C6H8O7 (aq) → NaC6H7O7 (aq) + CO2 (g) + H2O (l).