CAS 312-85-6 Sodium Lactate (HCID 23666456)

Überblick

Sodium lactate is an organic sodium salt having lactate as the counterion. It has a role as a food acidity regulator and a food preservative. It is a lactate salt and an organic sodium salt. It contains a lactate.

Namen und Bezeichner

Bevorzugter Name: Sodium Lactate
IUPAC: sodium 2-hydroxypropanoate
Lokaler Name: Natrium-(±)-lactat
Englischer Name: Sodium lactate
Summenformel: C3H5NaO3
Molmasse: 112.06

Namen und Synonyme

SODIUM LACTATE72-17-3Sodium DL-lactatesodium 2-hydroxypropanoateLactic acid sodium saltMonosodium lactateLacolinPer-glycerinLactic acid, monosodium saltSodium alpha-hydroxypropionateMonosodium 2-hydroxypropanoatePropanoic acid, 2-hydroxy-, monosodium salt

Weitere Namen anzeigen

SODIUM L-LACTATESODIUM L-LACTATE SOLUTIONPURASAL(R)SL-SODIUM LACTATEPURASAL(R)S/SP 60PURASAL(R)S/PF 60PURASAL(R)S/HQ 6040%solutionbyweightL-LACTIC ACID NA-SALT

Natrum lacticum2-Hydroxypropanoic acid, monosodium saltE325Mediject LTU7HW0W0QTSodium (lactate) anhydrousINS NO.325DTXSID6052829

Datenbank-Bezeichner

CAS: 312-85-6、72-17-3
PubChem CID: 23666456
DTXSID: DTXSID6052829
ChEMBL: CHEMBL1357
ChEBI: CHEBI:75228
UNII: TU7HW0W0QT
EC Number: 200-772-0、206-231-5
Nikkaji: J1.170C

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA): 60,4 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 3
Frei drehbare Bindungen: 1
Schwere Atome: 7
Formalladung: 0
Komplexität: 63,2

Experimentelle und physikochemische Eigenschaften

Chemical ClassesMetals -> Organic Acids, Metal Salts

Cosmetics · 2 Einträge

Cosmetic ingredients (Sodium Lactate) -> CIR (Cosmetic Ingredient Review)

Humectant; Buffering

pH6,5 to 7,5 (20 % aqueous solution)

Food AdditivesANTIMICROBIAL AGENT, EMULSIFIER OR EMULSIFIER SALT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, PH CONTROL AGENT, WASHING OR SURFACE REMOVAL AGENT -> FDA Substance added to food

Human Drugs · 3 Einträge

FDA approved drugs -> Active ingredient

Solutions correcting water, electrolyte and acid-base disturbances > Parenteral

Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List

Physikochemische Eigenschaften

Schmelzpunkt: 163 · 163-165 °C(lit.)
Dichte: 1.33 · 1.33
Brechungsindex: 1.422 · 1.422-1.425
storage temp.: 2 · 2-8°C
Aggregatzustand: syrup
Farbe: 50 APHA · 50 APHA max.
PH: 7.48 · 7.48(1 mM solution);7.85(10 mM solution);8.3(100 mM solution);8.61(1000 mM solution)
Stabilität: Stable.
CAS Datenbank: 312 · 312-85-6(CAS DataBase Reference)
EPA chemische Informationen: 2 · Propanoic acid, 2-hydroxy-, monosodium salt(312-85-6)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 11.3% (192 of 1703) of reports.

Danger

H315 (77.6%): Causes skin irritation [Warning Skin corrosion/irritation]

P264, P264+P265, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 1703 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This chemical does not meet GHS hazard criteria for 100% (25 of 25) of all reports.

Gefahrenhinweise

Regulatory Information · 5 Einträge

Chemical: Propanoic acid, 2-hydroxy-, monosodium salt

Regulation (EC) No 178/2002 (amended)

Propanoic acid, 2-hydroxy-, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Propanoic acid, 2-hydroxy-, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 22-12-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13477

Lactic acid, sodium salt: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Propanoic acid, 2-hydroxy-, monosodium salt: Human health tier I assessment

Hazards SummaryA mild eye irritant; Causes convulsions in acute intraperitoneal studies of rats; [RTECS] An eye irritant; [Sigma-Aldrich MSDS] See Lactic acid.

EPA Safer Chemical · 2 Einträge

Chemical: Sodium lactate

Hazard Classes and Categories · 2 Einträge

Skin Irrit. 2 (77.6%)

Not Classified

Sicherheit und Schutzausrüstung

Protective Action Criteria (PAC) · 6 Einträge

12 [mg/m3]

130 [mg/m3]

790 [mg/m3]

5.2 [mg/m3]

57 [mg/m3]

340 [mg/m3]

Toxikologische Informationen

Toxicity Summary · 2 Einträge

Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Sodium Lactate...

Safe for use in cosmetics, with qualifications

Drug Induced Liver Injury · 6 Einträge

Drug Induced Liver Injury Rank (DILIrank 2.0)

Sodium lactate

vNo-DILI-concern

0

No match

DOI:10.1016/j.drudis.2016.02.015

Sicherheitsdaten

F: 3-10
wgk: 1
RTECS-Nr.: OD5680000
safety_code: 24/25

Chemie und Industrie

Pharmakologische Informationen

ATC CodeB05BB01

Verwendung und Herstellung

Uses · 3 Einträge

CIR ingredient: Sodium Lactate

Used in calico printing (instead of glycerol), as a plasticizer for casein, and as a corrosion inhibitor in alcohol antifreeze mixtures; Also used therapeutically (electrolyte replenisher, alkalinizing agent, and treatment of bovine ketosis); [Merck Index] Used as a flavoring agent, antimicrobial agent, pH control agent, emulsifier, and washing or surface removal agent for foods; [FDA] Used as an antioxidant synergist, bodying agent, and humectant for foods; [JECFA]

Textiles (Printing, Dyeing, or Finishing) [Category: Industry]

U.S. Production2023: 6,477,653 lb

Consumer UsesPreservative

Industry UsesEtching agent

Household ProductsInformation on 37 consumer products that contain Sodium lactate in the following categories is provided:

Use Classification · 6 Einträge

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Food additives

Food Additives -> ANTIOXIDANT_SYNERGIST; HUMECTANT; SYNERGIST; THICKENER -> JECFA Functional Classes

Anwendungen · 1 Eintrag

Verwendensodium lactate keeps a product’s pH from becoming too acidic. It is moisturizing and moisture binding, as well as being a keratolytic, helping exfoliate excess cells from the surface of the stratum corneum. It is also used as a substitute for glycerin. Sodium lactate is naturally occurring in the skin.