Natrium-[2S-(2α,5α,6β)]-6-[[[3-(2,6-dichlorphenyl)-5-methylisoxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat
Dicloxacillin Sodium
Grundinformationen
- CAS
13412-64-1- Standard-SMILES
Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)N[C@@H]1C(=O)N2[C@@H]1SC(C)(C)[C@@H]2C(=O)[O-].[Na+]- InChIKey
GXOMMGAFBINOJY-SLINCCQESA-M- Summenformel
- C19H16Cl2N3NaO5S
- Durchschnittliche Molmasse
- 492,3 g/mol
- Monoisotopische Masse
- 491,0085415
Überblick
Dicloxacillin sodium is an organic sodium salt. It contains a dicloxacillin(1-).
Namen und Bezeichner
- Bevorzugter Name
- Dicloxacillin Sodium
- IUPAC
- sodium (2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
- Lokaler Name
- Natrium-[2S-(2α,5α,6β)]-6-[[[3-(2,6-dichlorphenyl)-5-methylisoxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat
- Englischer Name
- sodium [2S-(2alpha,5alpha,6beta)]-6-[[[3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate [3.2.0]
- Summenformel
- C19H18Cl2N3NaO5S
- Molmasse
- 494.32
Namen und Synonyme
Dicloxacillin sodium343-55-5Sodium dicloxacillinPathocilDycill4CKS6MOL6ZCHEBI:34691DTXSID60187861Dicloxacillinum natricumCHEBI:520194-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl penicillin sodium monohydrate
Weitere Namen anzeigen
P 1011BrispenNoxabenStampenDiclocilPen-SintConstaphyl
NSC-756726RefChem:920097DTXCID201103524HZT2V9KX0P-1011Dicloxacillin sodium saltDynapenDicloxacillin (sodium)
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 141 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 7
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 31
- Formalladung
- 0
- Komplexität
- 752
Experimentelle und physikochemische Eigenschaften
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Collision Cross Section202.7 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physikochemische Eigenschaften
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- Soluble in DMSO
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H315 (91.5%): Causes skin irritation [Warning Skin corrosion/irritation]
P233, P260, P261, P264, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 47 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]
Gefahrenhinweise
Regulatory Information
Dicloxacillin Sodium Monohydrate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Dicloxacillin sodium: Does not have an individual approval but may be used under an appropriate group standard
Other Safety Information
IMAP assessments - 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, [2S-(2.alpha.,5.alpha.,6.beta.)]-: Environment tier I assessment
IMAP assessments - 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-(2.alpha.,5.alpha.,6.beta.)]-: Human health tier I assessment
Hazard Classes and Categories
Skin Irrit. 2 (91.5%)
Skin Irrit. 2 (66.7%)
Toxikologische Informationen
Chemie und Industrie
Pharmakologische Informationen
FDA Pharmacological Classification
DICLOXACILLIN SODIUM
Penicillins [CS]; Penicillin-class Antibacterial [EPC]
MeSH Pharmacological ClassificationSubstances that inhibit the growth or reproduction of BACTERIA.
Anwendungen
Verwendenantibacterial
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