Fenaminosulf (ISO)

BeschreibungIntroduced in 1955, fenaminosulf (1; Lesan; Dexon) was one of the first selective, systemic fungicides. It is active against Phycomycetes such as Pythium, Phytophthora, and Aphanomyces but has little or no effect on higher fungi belonging to the Ascomycetes or Basidiomycetes. Fenaminosulf has a relatively high water solubility (20,000 mgL-1), a feature often associated with fungicides that specifically inhibit Oomycetes (3). Another important physicochemical property is photolytic instability, one of the reasons that fenaminosulf was developed as a seed dressing and soil fungicide (4). As a consequence of acute toxicity , limited spectrum, and photo-instability, the use of fenaminosulf decreased (4), and it is now listed in The Pesticide Manual (5) among products that have been superseded. Although no longer used, it is included here for completeness, being the only example of a commercial fungicide that acts on complex I. During its period of use, fenaminosulf, as wettable powder (WP), dust, or granular formulations, was employed as a seed dressing and soil-applied fungicide to control damping off and foot/root rots. Fenaminosulf-based products were used on a range of plants including vegetables, field crops, ornamentals, and turf.

VerwendenUsed in biological and pharmacological studies including:• ;Cloning and characterization of GABA transporter1• ;Activity of anti-RSV carbonucleosides2• ;Inhibition by fungicides of urea hydrolysis and nitrification of urea nitrogen in soil3