868-14-4O=C([O-])[C@H](O)[C@@H](O)C(=O)O.[K+]KYKNRZGSIGMXFH-ZVGUSBNCSA-MPotassium bitartrate is an organic potassium salt of L-tartaric acid. It is a by-product of winemaking and occurs naturally in grapes, the major fruit used to produce wine. It has a role as an antimicrobial agent, a laxative, a food acidity regulator, a plant metabolite, a food anticaking agent, a food stabiliser, a food humectant and a raising agent. It contains a L-tartrate(1-).
868-14-4DTXSID60423131.984 @ 18 °C
1.954 @25 °C
COLORLESS CRYSTALS OR WHITE, CRYSTALLINE POWDER
SLIGHTLY OPAQUE CRYSTALS
Partially soluble
1 G DISSOLVES IN 162 ML WATER, IN 16 ML BOILING WATER, IN 8820 ML ALCOHOL; READILY SOL IN DILUTED MINERAL ACIDS; SOL IN SOLN OF ALKALIES OR BORAX; IN WATER APPROX 0.4% @ 10 °C TO 6% @ 100 °C
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
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This chemical does not meet GHS hazard criteria for 100% (168 of 168) of all reports.
Not Classified
Aggregated GHS information provided per 168 reports by companies from 1 notifications to the ECHA C&L Inventory.
Chemical: Butanedioic acid, 2,3-dihydroxy- [R-(R*,R*)]-, monopotassium salt
Regulation (EC) No 1333/2008 (amended)
Status: Active Update: 03-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/11349
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, monopotassium salt: Does not have an individual approval but may be used under an appropriate group standard
Potassium bitartrate is a carbon dioxide-releasing laxative that works by forming carbon dioxide gas, which creates a mechanical distension against the intestinal wall and induces bowel contractions. Rectal suppositories of carbon dioxide-releasing type of laxative were demonstrated to be useful and safe in the treatment of patients at risk for electrolyte disorders such as the elderly or patients with renal or cardiovascular disorders.
There is little systemic absorption expected following rectal administration of potassium bitartrate.
No pharmacokinetic data available.
No pharmacokinetic data available.
No pharmacokinetic data available.
Used as a mordant in textile dyeing; [www.ci.tucson.az.us/arthazards/medium.html] Obtained from sediments of wine manufacturing; [Merck Index] Used for coloring and galvanic tinning of metals; as reducer of chromium trioxide in mordants for wool; in dusting powders for gloves; to make hard candies; in baking powders and baking mixes; as metal processing agent (prevents oxidation); as intermediate for other potassium tartrates; to remove sulfur dioxide from waste gases (in solution); as medical cathartic; as veterinary laxative and diuretic; [HSDB]
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Wird geladen…
CHEMBL2105248CHEBI:32034White crystalline or granulated powder
Colorless or white solid; [Merck Index] White powder; [MSDSonline]
COLORLESS, RHOMBIC CRYSTALS; SOL IN ACID, ALKALIES; INSOL IN ALC, ACETIC ACID; INDEX OF REFRACTION: 1.511, 1.550, 1.590 /D-FORM/
COLORLESS MONOCLINIC CRYSTALS; SOL IN MINERAL ACID, INSOL IN ALCOHOL; DENSITY: 1.954 /DL-FORM/
87 [mg/m3]
960 [mg/m3]
5800 [mg/m3]
Electroplating [Category: Plate]
Textile arts [Category: Hobbies]
COLORING METALS, GALVANIC TINNING OF METALS; REDUCER OF CHROMIUM TRIOXIDE IN MORDANTS FOR WOOL
DUSTING POWDER ON GLOVES
IN MANUFACTURE OF HARD CANDIES
(1972) No Data
(1975) No Data
(1972) 1.13X10+9 GRAMS
(1975) 4.57X10+8 GRAMS
(1972) GREATER THAN 4.54X10+5 GRAMS
(1975) GREATER THAN 4.54X10+5 GRAMS
REACTION OF TARTARIC ACID, POTASSIUM SODIUM TARTRATE (ROCHELLE SALT), AND POTASSIUM SULFATE, FOLLOWED BY FILTRATION, PURIFICATION, PRECIPITATION, & DRYING
OBTAINED FROM SEDIMENTS IN MANUFACTURE OF WINE, KNOWN AS ARGOLS OR WINE LEES. SALT IS @ LEAST 99.5% PURE.
BY PURIFYING ARGOL OR TARTAR- SUBSTANCE DEPOSITED IN WINE CASKS DURING FERMENTATION OF GRAPE JUICE, WHICH SUBSTANCE CONSISTS OF ABOUT 80% POTASSIUM BITARTRATE.
FROM WINE LEES BY EXTRACTION WITH WATER & CRYSTALLIZATION.
THIS SALT IS ONE OF THE INGREDIENTS IN COMPD JALAP POWDER, FORMERLY IN THE NF.
SALT IS @ LEAST 99.5% PURE.
GRADES: TECHNICAL; NF; FCC.
EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives
Safer Chemical Classes -> Green half-circle - The chemical is expected to be of low concern
Food additives
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, potassium salt (1:1): ACTIVE
INCOMPATIBILITIES: BECAUSE IT CONTAINS AN ACIDIC HYDROGEN, IT CAN REACT WITH ALKALINE SUBSTANCES. ITS SLIGHT SOLUBILITY SOMETIMES CAUSES DIFFICULTY IN LIQ MIXTURES.
BeschreibungL (+)-Potassium hydrogen tartrate (also known as potassium bitartrate) is the potassiumacid salt of tartaric acid (a carboxylic acid). It is the byproduct during the winemaking process. It can be used in baking or as a cleaning solution. When mixed with an acidic liquid such as lemon juice or white vinegar, it can be made of a paste-like cleaning agent for metals or some other cleaning applications. It can also be used as a pH buffer component in chemistry. It has been recently shown that it is capable of treating breast cancer. Approved by the FDA as a direct food substance, potassium bitartrate is used as an additive, stabilizer, pH control agent, antimicrobial agent, processing aid, or thickener in various food products. Potassium bitartrate has a long history of medical use as a laxative administered as a rectal suppository and is an approved third-class OTC drug in Japan. Potassium bitartrate was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.
OccurrencePotassium bitartrate crystallizes in wine casks during the fermentation of grape juice, and can precipitate out of wine in bottles.The crystals (wine diamonds) will often form on the underside of a cork in wine-filled bottles that have been stored at temperatures below 10°C , and will seldom, if ever, dissolve naturally into the wine. These crystals also precipitate out of fresh grape juice that has been chilled or allowed to stand for some time. To prevent crystals forming in homemade grape jam or jelly, fresh grape juice should be chilled overnight to promote crystallisation. The potassium bitartrate crystals are removed by filtering through two layers of cheesecloth. The filtered juice may then be made into jam or jelly. In some cases they adhere to the side of the chilled container, making filtering unnecessary. The crude form (known as beeswing) is collected and purified to produce the white, odorless, acidic powder used for many culinary and other household purposes.
VerwendenLargely in baking powders; coloring metals, galvanic tinning of metals; reducer of CrO3 in mordants for wool.
synthetischepotassium bitartrate is mainly produced from the mother liquor of Seignette's salt. These decolorized, purified, and filtered solutions are acidified to pH 3.5 with hydrochloric or sulfuric acid. Since cream of tartar is sparingly soluble, it precipitates and is recovered by centrifugation, dried, and ground before being packaged as fine powder.