Diphosphorsure, Kaliumsalz

Cosmetic ingredients (Tetrapotassium Pyrophosphate) -> CIR (Cosmetic Ingredient Review)

Buffering; Chelating

Soluble in water, insoluble in ethanol

Solubility in water, g/100ml at 25 °C: 187 (very good)

1090 °C

180 °C

Potassium tetrapyrophosphate is a whitish-colored powdered solid. It is toxic by ingestion, and/or inhalation. Contact with the substance should be avoided.

Liquid; Other Solid; Dry Powder; Liquid; Liquid; CBI; Large Crystals; Other Solid; Dry Powder

Colourless crystals or white, very hygroscopic powder

Trihydrate: Colorless deliquescent solid; [Merck Index] White odorless solid; Hygroscopic; [ICSC] White hygroscopic powder or granules; [Alfa Aesar MSDS]

ODOURLESS HYGROSCOPIC WHITE GRANULES OR POWDER.

This chemical does not meet GHS hazard criteria for 2.3% (62 of 2678) of reports.

Warning

H319 (96.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)

Aggregated GHS information provided per 2678 reports by companies from 17 notifications to the ECHA C&L Inventory.

Chemical: Diphosphoric acid, tetrapotassium salt

Diphosphoric acid, potassium salt (1:4) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Diphosphoric acid, potassium salt (1:4) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 09-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14700

Tetrapotassium pyrophosphate: Does not have an individual approval but may be used under an appropriate group standard

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

Causes somnolence and gastrointestinal changes in oral lethal-dose studies of rats; Causes changes in renal tubules and weight loss in 13-week oral studies of rats; [RTECS] Causes burns; Inhalation of aerosol may cause pulmonary edema; [ICSC] A skin and strong eye irritant; [Alfa Aesar MSDS] See Potassium phosphate, tribasic, Potassium phosphate, dibasic, Potassium metaphosphate, and Pentapotassium triphosphate.

Salts, basic, such as POTASSIUM TETRAPYRO PHOSPHATE, are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

In case of fire in the surroundings, use appropriate extinguishing media.

Fresh air, rest. Half-upright position. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Refer for medical attention .

The CIR Expert Panel concluded that the following 31 ingredients are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating...Tetrapotassium Pyrophosphate...

Safe for use in cosmetics, with qualifications

Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed.

Redness. Skin burns. Pain. Blisters.

Redness. Pain. Severe deep burns.

Abdominal pain. Burning sensation. Shock or collapse. Sore throat.

1

PPRTV Current

4

PPRTV Current

7.80e+04

1.20e+06

2.00e+04

1.5E+01(G)

1.00e+00

Volatile

2.30e+05

3.50e+06

6.00e+04

1.5E+01 (G)

1.00e+00

Volatile

CIR ingredient: Tetrapotassium Pyrophosphate

Used in detergents and surfactants, water treatment, and as a clay thinner in drilling muds; [Merck Index] Used in the chemical and personal-domestic use industries, as a food additive, cleaning/washing agent, disinfectant, and in pharmaceuticals; [IUCLID] Used in tin plating, stabilizing hydrogen peroxide baths, purification of chin clay, oil drilling muds, soaps and detergents (sequesters magnesium), peptizing curds of calcium soap, building/clarifying of liquid soaps in synthetic rubber production, as an iron sequestrant, peptizer in latex paints, in ultra high pressure boiler water treatment, and as an emulsifier and texturizer in foods; [EPA OHM/TADS] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]

Electroplating [Category: Plate]

EPA Safer Chemical Functional Use Classes -> Oxidants and Oxidant Stabilizers

Safer Chemical Classes -> Yellow triangle - The chemical has met Safer Choice Criteria for its functional ingredient-class, but has some hazard profile issues

Food additives

Food Additives -> EMULSIFIER; TEXTURIZER; THICKENER -> JECFA Functional Classes

Food Additives -> EMULSIFIER; TEXTURIZER; THICKENER -> JECFA Functional Classes

Food Additives -> EMULSIFIER; TEXTURIZER; THICKENER -> JECFA Functional Classes

Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing

Diphosphoric acid, potassium salt (1:4): ACTIVE