HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Propin-1-amin
Prop-2-yn-1-amine · 2-PROPYNYLAMINE · 2-propyn-1-amine · POTASSIUM TER-BUTOXIDE · Propargulamine · MONO-PROPARGYLAMINE · Propargylamin · Prop-2-ynylamine
Identifikatoren & physikalische Daten
| CAS No. | 2450-71-7 |
|---|---|
| Summenformel | C3H5N |
| Durchschnittliche Molmasse | 55,08 g/mol |
| Monoisotopische Masse | 55,04219916 g/mol |
| SMILES | C#CCN |
| InChIKey | JKANAVGODYYCQF-UHFFFAOYSA-N |
| PubChem CID | 239041 |
| ChEMBL | CHEMBL3263480 |
| EC No. | 219-513-8 |
| DTXSID | DTXSID30862951 |
| Lokaler Name | 2-Propin-1-amin |
Chemische & physikalische Eigenschaften
| XLogP | -0,4 |
|---|---|
| Polarare Oberfläche (TPSA) | 26 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 4 |
| Formalladung | 0 |
| Komplexität | 38 |
| Siedepunkt | 84 °C |
| Dichte | 0.86 |
| Brechungsindex | n20/D 1.449(lit.) |
| Flammpunkt | 39 °F |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | soluble in Chloroform, Ethyl Acetatemiscible |
| Aggregatzustand | Liquid |
| pKa (Säurekonstante) | 7.89±0.29(Predicted) |
| Farbe | Clear colorless to yellow |
| BRN | 773681 |
| Dielektrizitätskonstante | 6.6500000000000004 |
| InChI | 1S/C3H5N/c1-2-3-4/h1H,3-4H2 |
| InChIKey | JKANAVGODYYCQF-UHFFFAOYSA-N |
| SMILES | NCC#C |
| CAS Datenbank | 2450-71-7(CAS DataBase Reference) |
| NIST chemische Informationen | Propargylamine(2450-71-7) |
| EPA chemische Informationen | 2-Propyn-1-amine (2450-71-7) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]H310 (98.2%): Fatal in contact with skin [Danger Acute toxicity, dermal]H314 (92.9%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H318 (64.3%): Causes serious eye damage [Danger Serious eye damage/eye irritation]P210, P233, P240, P241, P242, P243, P260, P262, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P361+P364, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 168 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Chemical: 2-Propyn-1-amine |
| Hazard Classes and Categories | Flam. Liq. 2 (100%)Acute Tox. 4 (100%)Acute Tox. 2 (98.2%)Skin Corr. 1C (92.9%)Eye Dam. 1 (64.3%) |
| F | 3-8-10-34 |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 1992 3/PG 2 |
| Zollcode | 29211990 |
| RTECS-Nr. | UK5250000 |
| R-Sätze (R) | 11-22-24-34 |
| Gefahrensymbole | F,T |
| Sicherheitshinweise (S) |
Anwendungen & Verwendung
Verwenden
Propargylamine is used in the synthesis of a chiral, a fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene. It acts as an intermediate in the production of drugs.