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HCID 24424Erstellt: 27. Oktober 2026

Zinksulfat

ZINC SULFATE · ZnSO4 · ZDDP · Zinksulfat · Zinc sulphat · sulphate zinc · Zinc(II) sulfate · Zinc sulfate (ZnSO4)

https://huagongshe.com/de/chemical/24424

Molekülstruktur von Zinksulfat

Identifikatoren & physikalische Daten

CAS No.7733-02-0
SummenformelZnSO4
Durchschnittliche Molmasse161,4 g/mol
Monoisotopische Masse159,88087168 g/mol
SMILESO=S(=O)([O-])[O-].[Zn+2]
InChIKeyNWONKYPBYAMBJT-UHFFFAOYSA-L
PubChem CID24424
ChEMBLCHEMBL1200929
ChEBICHEBI:35176
EC No.231-793-3
DTXSIDDTXSID2040315
Lokaler NameZinksulfat

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)88,6
H-Brücken-Donoren0
H-Brücken-Akzeptoren4
Frei drehbare Bindungen0
Schwere Atome6
Formalladung0
Komplexität62,2
StoffklassenMetals -> Metals, Inorganic Compounds
KosmetikaCosmetic ingredients (Zinc Sulfate) -> CIR (Cosmetic Ingredient Review)Oral careAntiplaqueAntimicrobialAnticaking
LogP (Verteilungskoeffizient)-0.07
Dichte1.96 at 68 °F (USCG, 1999) - Denser than waterwill sink3.8 g/cu cm3.8 g/cm³3.74 @ 15°C1.31 g/mL at 20 °C
Color/FormColorless, orthorhombic crystals
LöslichkeitSolubility: 54.480 lb/100 lb water /Heptahydrate/57.7 g/100 g water at 25 °CIn water solubility, 101 g/100 g water at 70 °CSolubility in water, g/100ml at 20 °C: 22 (good)H2O: soluble
Human DrugsFDA approved drugs -> Active ingredientMedicines for diarrhoea
DecompositionWhen heated to decomposition it emits toxic fumes of /sulfur oxides and zinc oxide/.680 °C
Schmelzpunkt212 °F (USCG, 1999)680 °C (decomposes)100°C
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical DescriptionAnhydrous zinc sulfate is a colorless crystalline solid. Zinc sulfate is also obtained as a hexahydrate, ZnSO4.6H2O, and as a heptahydrate ZnSO4.7H2O. All forms are soluble in water. All are noncombustible. The primary hazard is the threat posed to the environment. Immediate steps should be taken to limit its spread to the environment. It is used in the production of rayon, as a feed supplement, and as a fertilizer ingredient.CBILarge CrystalsOther SolidWet SolidDry PowderLiquidColorless crystals. [HSDB]COLOURLESS HYGROSCOPIC CRYSTALS.
Stability/Shelf LifeThere is ... /a/ tendency for solutions of zinc sulfate to form slight cloudiness due to seperation of basic salt formed through partial hydrolysis.
Siedepunkt105°C (estimate)
LagerbedingungenStore at +15°C to +25°C.
AggregatzustandLiquid
FarbeColorless
pH4.0±0.5
Spezifische WärmekapazitätCp(crystal): 0.61 J/(g·K), at 25℃
Merck14,10159
Kosmetik-Inhaltsstoffe FunktionenORAL CAREASTRINGENTANTIPLAQUEANTIMICROBIAL
InChI1S/H2O4S.Zn/c1-5(2,3)4/h(H2,1,2,3,4)/q+2/p-2
InChIKeyNWONKYPBYAMBJT-UHFFFAOYSA-L
SMILES[Zn++].[O-]S([O-])(=O)=O
LogP (Verteilungskoeffizient)-1.031 (est)
CAS Datenbank7733-02-0(CAS DataBase Reference)
NIST chemische InformationenZinc sulfate(7733-02-0)
EPA chemische InformationenZinc sulfate (7733-02-0)

Sicherheit & Vorschriften

GHS-EinstufungDangerH302: Harmful if swallowed [Warning Acute toxicity, oral]P264, P264+P265, P270, P273, P280, P301+P317, P305+P354+P338, P317, P330, P391, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for 0.1% (1 of 928) of reports.H302 (94.2%): Harmful if swallowed [Warning Acute toxicity, oral]
Regulatorische InformationenChemical: Sulfuric acid, zinc salt (1:1)Sulfuric acid, zinc salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfuric acid, zinc salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 27-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15488Zinc sulphate: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
Weitere SicherheitsinformationenIMAP assessments - Soluble zinc salts: Human health tier II assessment
DOT-KennzeichnungClass 9
BrandgefahrenExcerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:Not combustible.
BrandpotenzialNon-combustible
GesundheitsgefahrenInhalation of dust causes irritation of nose and throat. Ingestion can cause irritation or corrosion of the alimentary tract. Contact with eyes or skin causes irritation. (USCG, 1999)
GefahrenübersichtToxic by ingestionLong-term therapeutic doses may inhibit the absorption of copperZinc sulfate was used as an emetic (dose of 1-2 grams in a glass of water) in the past, but it can cause kidney injury. The dust is irritating to the nose and throat. Subjects receiving 200 mg three times a day for 18 weeks showed no signs of kidney or liver injury. Ingestion of 28 grams was lethal in one poisoning case. Autopsy showed pancreatic hemorrhage and renal damage. [HSDB] See Zinc.

Anwendungen & Verwendung

Verwenden

The principal commercial preparation of zinc sulfate is the monohydrate granular (36% of zinc) used as a fertilizer. It is also a component of spinning bath in the production of rayon, carbamate fungicides, zinc plating baths, and ophthalmic solutions. Zinc sulfate is used as an accelerating agent in dental impression material, froth flotation agent, and animal feed additive.

FDA-AnforderungenThis substance is generally recognized as safe when used as a nutrient in accordance with good manufacturing practice.This substance is generally recognized as safe when used as a nutrient and/or dietary supplement in accordance with good manufacturing or feeding practice.Substances migrating to food from paper and paperboard products used in food packaging that are generally recognized as safe for their intended use, within the meaning of section 409 of the Act. Zinc sulfate is included on this list.Trace minerals added to animal feeds as nutritional dietary supplements are generally recognized as safe when added at levels consistent with good feeding practice. Zinc sulfate is included on this list.For more FDA Requirements (Complete) data for ZINC SULFATE (8 total), please visit the HSDB record page.
Reaktive GruppeSalts, Acidic
EG-EinstufungSymbol: Xn, NR: 22-41-50/53S: (2)-22-26-39-46-60-61
UN-EinstufungUN Hazard Class: 9UN Pack Group: III
FIFRA-AnforderungenResidues of zinc sulfate (basic and monohydrate) are exempted from the requirement of a tolerance when used as a coating agent in accordance with good agricultural practices as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest.Residues of zinc sulfate (basic and monohydrate) are exempted from the requirement of a tolerance when used as a solid diluent, carrier in accordance with good agricultural practices as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest.Zinc sulfate (basic and monohydrate) is exempted from the requirement of a tolerance when used as a water repellant, desiccant, and coating agent in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to animals.The Agency has sufficient information on the human health effects of zinc salts and on it potential for causing effects in fish and wildlife and the environment when used to control moss and fungus growth in outdoor residential areas, on structures, in pressure-treated lumber and incorporated into fibers used in carpet. The Agency concludes that products containing zinc salts for these uses ar eligible for reregistration. Only certain generic physical chemistry data studies on zinc salts still are needed as comfirmatory information. The Agency has determined tha zinc salt containing products, labeled and used as specified in this Reregistration Eligibility Document will not pose unreasonable risks or adverse effects to humans or the environment.As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA, as amended in 1988, were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Zinc sulfate, basic is found on List D. Case No: 4099Pesticide type: fungicide, herbicide, antimicrobialCase Status: RED Approved 09/92OPP has made a decision that some/all uses of the pesticide are eligible for reregistration, as reflected in a Reregistration Eligibility Decision (RED) document .Active ingredient (AI): Zinc sulfate, basicAI Status: The active ingredient is no longer contained in any registered pesticide products ... "cancelled."
BrandbekämpfungExcerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:In case of fire in the surroundings, use appropriate extinguishing media.
Erste-Hilfe-MaßnahmenFresh air, rest. Seek medical attention if you feel unwell.Rinse skin with plenty of water or shower.Rinse with plenty of water for several minutes (remove contact lenses if easily possible).Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
Erste HilfeINHALATION: move to fresh air.
Sichere LagerungDry. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.
Expositionsschutz und Persönliche Schutzausrüstung0.1 [mg/m3] (respirable fraction), 2 mg/m3 (inhalable fraction) for Zn inorg. cmpnds[German Research Foundation (DFG)]
BrandbekämpfungsverfahrenIf material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or burns with difficulty.
LagerbedingungenZinc sulfate ophthalmic solutions should be stored in tightly closed containers at temperatures not exceeding 40 °C, freezing should be avoided.Finely divided ... zinc compounds, can be fire and explosion hazard if stored in damp places, sources of spontaneous combustion. /Zinc cmpd/There is ... /a/ tendency for solutions of zinc sulfate to form slight cloudiness due to seperation of basic salt formed through partial hydrolysis.
ReinigungsverfahrenEnvironmental considerations: Land spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be contained with a flexible impermeable membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.Environmental considerations: Water spill: Neutralize with agricultural lime, crushed limestone or sodium bicarbonate. Add soda ash. Adjust pH to neutral (pH= 7). Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.
Freisetung ohne BrandExcerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:
EntsorgungsverfahrenSRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air qualitypotential migration in soil or watereffects on animal, aquatic, and plant lifeand conformance with environmental and public health regulations.Chemical Treatability of ZincConcentration Process: UltrafiltrationChemical Classification: MetalsScale of Study: Continuous flow, pilot scaleType of Wastewater Used: Industrial wastewaterResults of Study: 0.38 ppm effluent concentration. /Zinc/Concentration Process: Miscellaneous sorbentsScale of Study: Literature reviewType of Wastewater Used: UnknownResults of Study: Final concentration reduced to 0.1 ppbSiO2 + CaO slags used. /Zinc/The proprietary Sulfex process (Permutit Co) has been applied to zinc wastes. The process involves addition of ferrous sulfide, which gradually releases sulfide to precipitate the zinc ... . /Zinc/For more Disposal Methods (Complete) data for ZINC SULFATE (11 total), please visit the HSDB record page.
Verschüttetes entsorgenPersonal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting.
Preventive MeasuresIf material not on fire and not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow if necessary. Keep upwind. Avoid breathing vapors or dust. Wash away any material which may have contacted the body with copious amounts of water or soap and water.SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.Prevention ... /of metal fume fever/ is a matter of keeping exposure of workers below level of concn currently accepted as satisfactory for working with the metal in industry, preferably by employment of proper local exhaust ventilation to collect fumes at their source. Acceptable respirators are avail commercially but should be used only under suitable conditions. /Zinc/In all cases where zinc is heated to the point where fume is produced, it is most important to ensure that adequate ventilation is provided. Individual protection is best ensured by education of the worker concerning metal-fume fever & the provision of local exhaust ventilation, or, in some situations by wearing of supplied-air hood or mask.
TreatmentZinc poisoning is treated symptomatically, often by administering fluids such as water or milk, or with gastric lavage. (L49)
WechselwirkungenThe effects of intraperitoneal pretreatment, 48 hr beforehand, with zinc sulfate (22, 44 or 88 mg/kg) were studied on gastric ulceration, gastric secretion and changes in stomach wall mast cell counts induced after 4 hr by reserpine (5 mg/kg) given intraperitoneally to intact (unoperated for pylorus occlusion) or pylorus-occluded rats. Zinc sulfate dose-dependently antagonized the gastric actions of reserpine by preventing ulceration in the ruminal and glandular segments of the stomach, reducing acid secretion, and inhibiting mast cell degranulation which occurred mainly in the glandular mucosal layer. The relationship between these findings and the action of zinc on gastric mast cell is discussed.Concurrent use of large amounts of fiber, phosphorus, or phytates with zinc supplements may reduce zinc absorption by formation of nonabsorbable complexesfood containing fiber, phosphorus, or phytates should be taken at least 2 hours after zinc supplements. /Zinc supplements/Some studies have found that folate can decrease the absorption of zinc, but not in the presence of excessive zincother studies have found no inhibition. /Zinc supplements/Large doses of iron supplements can inhibit the intestinal absorption of zincthis, at one time was a problem in individuals taking commercial multivitamin-mineral preparations or infant formulas that had a high iron to zinc ratiohowever, most firms in the US have reformulated their productszinc supplements should be taken at least 2 hours after iron supplements. /Zinc supplements/For more Interactions (Complete) data for ZINC SULFATE (16 total), please visit the HSDB record page.
Gesundheitliche AuswirkungenChronic exposure to zinc causes anemia, atazia, lethargy, and decreases the level of good cholesterol in the body. It is also believed to cause pancreatic and reproductive damage. (L49)
ÖkotoxizitätswerteLC50 Anguilla japonica (Japanese eel) 29 mg/L/24 hr, 14 mg/L/48 hr, 11 mg/L/96 hrstaticTLm Noemacheilus montanus 2.37 ppm/24 hr, 1.50 ppm/48 hr, 0.95 ppm/72 hr, 0.62 ppm 96 hr /Conditions of bioassay not specified/LC50 Scylla serrata on (immature marine edible crab), were 741.3 ppm/24 hr, 645.7 ppm/48 hr, 489.8 ppm/72 hr, and 398.1 ppm/96 hr in static bioassays/ after 24, 48, 72 and 96 hr, respectively.LC50 Lebistes reticulatus (guppy, male) 300 mg/L/96 hr /Conditions of bioassay not specified/For more Ecotoxicity Values (Complete) data for ZINC SULFATE (113 total), please visit the HSDB record page.
ExpositionspfadeThe substance can be absorbed into the body by ingestion.Inhalation (L49)oral (L49)dermal (L49)
ToxizitätsübersichtThe CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Sulfate...Safe for use in cosmetics, with qualificationsAnaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49)
Ökotoxizitätsauszüge/AQUATIC SPECIES/ The toxicity of zinc sulfate to Lepidocephalichthyes guntea /fish/ was reduced with increased water hardness. A 3.2 fold decrease in zinc (Zn) toxicity was noted at 260 mg/L of hardness on 96 hr exposure./AQUATIC SPECIES/ In flagfish /Jordanella floridae/ (not exposed as embryos to zinc), survival of larvae and growth of females were the most sensitive parameters of zinc toxicity and were reduced at 85 and 51 ug/L and above, respectively. In contrast, exposure at the embryo stage showed that embryo hatchability, and survival and growth of larvae were not affected significantly at 139 ug/L or below. ...The early life stage test was performed with enough embryos incubated in each test concentration (or control) to provide 30 1-day old larvae per concentration level. Reproduction tests were initiated after 30 or more embryos (not previously exposed) had emerged from any spawning substrate. /Heptahydrate//AQUATIC SPECIES/ In a /flow-through/ life cycle /(8 month exposure period)/ experiment, (i) the eight week survival of /Pimephales promelas/ (fathead minnows) exposed to zinc as eggs was reduced at mean concentrations of 0.295 and 0.576 mg/L, and (ii) the survival of fish exposed as larvae was also reduced at these two concentrations. During life-cycle exposure, the most sensitive parameters for toxicity were egg adhesiveness and fragility, which were significantly affected at 0.145 mg/L and above, but without effect at 0.078 mg/L and below. Reduced egg adhesiveness and increased fragility were not related to exposure of parental fish, which apparently developed normally at 0.145 and 0.295 mg/L. Hatchability and survival of larvae were significantly reduced, and deformities at hatching were significantly increased at 0.259 mg/L and above. NOEC (survival, hatchability): 0.145 mg/LNOEC (maturation, reproduction): 0.295 mg/L. ...Test conditions: water hardness: 46 mg/L CaCO3test medium: lake water. /Heptahydrate//AQUATIC SPECIES/ Effects of anthropogenic pollution have been observed at different trophic levels in the oceans, and toxicity tests constitute one way of monitoring these alterations. The present assay proposes the use of two reference substances, sodium dodecyl sulfate (SDS) and zinc sulfate, for Perna perna larvae. This common mussel on the Brazilian coast is used as a bioindicator and is of economic interest. The chronic static embryo-larval test of short duration (48 hr) was employed to determine the NOEC, LOEC, and IC50 for SDS and zinc sulfate, as well as the coefficient of variation. Salinity, pH and un-ionized ammonia (NH3) and dissolved oxygen (DO) concentrations were measured to monitor water quality. The results demonstrated that the main alterations in veliger larvae are the development of only one shell, protruded mantle, malformed shell, formation of only part of a valve, clipped edges, uneven sizes and presence of a concave or convex hinge. NOEC values were lower than 0.25 mg/L(-1) for zinc sulfate and 0.68 mg L(-1) for SDS. The coefficient of variation was 17.63% and 2.50% for zinc sulfate and SDS, respectively.For more Ecotoxicity Excerpts (Complete) data for ZINC SULFATE (6 total), please visit the HSDB record page.
Signs and SymptomsCough. Sore throat.Redness.Redness. Pain.Abdominal pain. Nausea. Vomiting.Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation. (L49)
Acute Toxicity LinkChemical: ZINC SULFATE
ICSC Environmental DataThe substance is very toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment.
Medical SurveillanceThe assessment of zinc exposure can be accomplished through measurement of zinc. The presence of excess zinc ... can indicate high exposure to zinchowever, no information was found in the literature regarding the accuracy of these levels in predicting possible health effects. Blood Reference Ranges: Normal - average level 1200 ug/dlExposed - not establishedToxic - not established. Serum or Plasma Reference Ranges: Normal - average levels 100 ug/dlToxic - not established. Urine Reference Ranges: Normal - average levels 0.5 mg/g creatinine or 150 to 1200 ug/24 hoursExposed - urinary concentrations of 600 to 700 ug/l were found in workers exposed to zinc oxide at levels of 3 to 5 mg/cu mToxic - greater than 1200 ug/24 hours has been indicated as a toxic urinary level of zinchowever no information was located relating to the severity of symptoms seen with high urinary zinc levels. /Zinc/Respiratory Symptom Questionnaires: Questionnaires have been published by the American Thoracic Society and the British Medical Research Council. These questionnaires have been found to be useful in identification of people with chronic bronchitis, however certain pulmonary function tests such as FEV1 have been found to be better predictors of chronic airflow obstruction. /Zinc/Chest Radiography: This test is widely used for assessing pulmonary disease. Chest radiographs have been found to be useful for detection of early lung cancer in asymptomatic people, especially for detection of peripheral tumors such as adenocarcinomas. However, even though OSHA mandates this test for exposure to some toxicants such as asbestos, there are conflicting views on its efficacy in detection of pulmonary disease. /Zinc/Pulmonary Function Tests: The tests that have been found to be practical for population monitoring include: Spirometry and expiratory flow-volume curvesDetermination of lung volumesDiffusing capacity for carbon monoxideSingle-breath nitrogen washoutInhalation challenge testsSerial measurements of peak expiratory flowExercise testing. /Zinc/For more Medical Surveillance (Complete) data for ZINC SULFATE (8 total), please visit the HSDB record page.
Human Toxicity Excerpts/HUMAN EXPOSURE STUDIES/ In a double-blind cross-over trial 47 healthy volunteers (26 females and 21 men) ingested zinc sulfate capsules containing 220 mg zinc sulfate, three times a day with each meal (resulting in a total daily dose of 150 mg Zn2+ ie, ca 2.1 and 2.5 mg Zn2+/kg bw /day for males and females, respectively) for six weeks. Plasma zinc and copper levels, plasma cholesterol, plasma low-density-lipoprotein (LDL) and high-density-lipoprotein (HDL) cholesterol, serum ceruloplasmin and erythrocyte superoxide dismutase (ESOD) were determined. In 84% of the women and 18% of the men symptoms were reported which included headaches, nausea, vomiting, loss of appetite and abdominal cramps. The study authors reported that the gastric discomfort went together with lower body weights and taking the capsules with small meals (breakfast or morning tea) or no food. Plasma zinc levels rose significantly in both men and women (36% and 57%, respectively). Plasma copper levels did not change significantly. Total plasma cholesterol and HDL were unchanged in both sexes. In females the LDL cholesterol decreased significantly from 2.38 to 2.17 mmol/L. In females a decrease was also found in serum ceruloplasmin (13% reduction) and in ESOD (ca. 20% reduction)./HUMAN EXPOSURE STUDIES/ In two studies the side effects of zinc administration as a medication in the treatment chronic leg ulcers was investigated: In a double-blind trial, 13 humans received 200 mg zinc sulfate (+/- 135 mg Zn2+) three times a day for 18 weeks, while 14 humans received a placebo. No signs of nephrotoxicity associated with the zinc treatment were reported ... No indications for hematotoxicity, hepatotoxicity or nephrotoxicity, as determined by several clinical biochemical and hematological parameters, were seen in 18 humans after administration of 220 mg zinc sulfate (150 mg Zn2+) 3 times a day for 16 to 26 weeks./SIGNS AND SYMPTOMS/ Intranasal irrigation with ZnSO4 is known to produce anosmia./SIGNS AND SYMPTOMS/ Acute overdose: Profuse sweating, decreased consciousness, blurred vision, tachycardia, hypothermia, hyperamylasemia, hypotension, pulmonary edema, diarrhea, vomiting, jaundice, oliguriaFor more Human Toxicity Excerpts (Complete) data for ZINC SULFATE (21 total), please visit the HSDB record page.
CERCLA-MeldepflichtmengenPersons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1,000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).
Clean Water Act AnforderungenZinc sulfate is designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. This designation includes any isomers and hydrates, as well as any solutions and mixtures containing this substance.Toxic pollutant designated pursuant to section 307(a)(1) of the Federal Water Pollution Control Act and is subject to effluent limitations. /Zinc and compounds/For total recoverable zinc the criterion-to protect freshwater aquatic life ... is 47 ng/L as a 24 hr average ... at hardnesses of 50, 100, and 200 mg/l as CaCO3 the concentration of total recoverable zinc should not exceed 180, 320, 570 ug/L at any time. /Soluble zinc salts/For total recoverable zinc the criterion to protect saltwater aquatic life ... is 58 ug/L as a 24 hr average and the concentration should not exceed 170 ug/L at any time. /Soluble zinc salts/
Landesrichtlinien für Trinkwasser(AZ) ARIZONA 5000 ug/l /Zinc/(MN) MINNESOTA 2000 ug/l /Zinc/
Bundesrichtlinien für TrinkwasserEPA 5000 ug/L /Zinc/EPA 2000 ug/L /Zinc, Lifetime health advisory/
Wassergefährdungsklasse (WGK)3
TSCA-Inventar-StatusTSCA listed
UN-TransportnummerUN 3082 9/PG 3
Zollcode2833 29 20
RTECS-Nr.ZH5260000
R-Sätze (R)52/53-50/53-41-22-51/53
GefahrensymboleXn,N,Xi
Sicherheitshinweise (S)61-39-26-60
Gefahrenklasse9Aquatic Chronic 2Eye Dam. 1
VerpackungsgruppeIII
Lagerklasse12 - Non Combustible Liquids
Gefahrstoffdaten7733-02-0(Hazardous Substances Data)