Ammonium sulfamate

Pesticide -> EPA IRIS

Agrochemicals -> Pesticide active substances

Active substance -> EU Pesticides database: Not approved

Pesticides -> Herbicides, Other

greater than 1 at 68 °F (USCG, 1999)

Sp. Gr. = 1.77

Relative density (water = 1): 1.8

1.77

1.77 no temp

1.77

Hygroscopic crystals (large plates)

Colorless to white crystalline solid

Deliquescent crystals

200 % (NIOSH, 2024)

Extremely sol in liquid NH3; slightly sol in ethanol; moderately sol in glycerol, glycol, formamide.

Sol in water and ammonia solution

Sol in water = 103 g/100 g @ 25 °C

Solubility in water: very good

200%

Decomposes above 392.0 °F (USCG, 1999)

160 °C

Boiling point: 107 °C /60 wt % solution/

320 °F (decomposes)

320 °F (Decomposes)

Toxic gases and vapors (such as ... carbon monoxide) may be released when ammonium sulfamate decomposes.

Thermal decomposition begins at 209 °C; at 260 °C, it produces sulfur dioxide, sulfur trioxide, nitrogen, water, and traces of other products, chiefly nitrogen compounds.

When heated to decomp ... emits very toxic fumes of /ammonia, nitrogen oxides and sulfur oxides/.

Decomposes at 160 °C.

160 °C

268 °F (USCG, 1999)

131 °C

MELTING POINT: 131-132 °C; PH: 5.2 (50 G/KG WATER) /TECHNICAL PRODUCT/

131 °C

268 °F

131 °C

0 mmHg (approx) (NIOSH, 2024)

0 mm Hg (approx)

Vapor pressure at 20 °C: negligible

0 mmHg (approx)

0 mmHg (approx)

This chemical does not meet GHS hazard criteria for 53.7% (151 of 281) of all reports.

Warning

H302 (46.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P273, P301+P317, P330, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 281 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This chemical does not meet GHS hazard criteria for 100% (2 of 2) of all reports.

Chemical: Sulfamic acid, monoammonium salt

Chemical: Sulfamic acid, ammonium salt

Sulfamic acid, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfamic acid, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

2006/797/EC

Status: Active Update: 08-03-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/25230

Sulfamic acid, ammonium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fires. (USCG, 1999)

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

A slightly toxic contact herbicide; [EXTOXNET] The following herbicides have an oral LD50 of >1 gm/kg and have little or no acute toxicity in humans: Alachlor, Amitrole, Ammonium sulfamate, Atrazine, Dalapon, Dicamba, Glyphosphate, Monuron, Oryzalin, Picloram, Propanil, Simazine, etc. [LaDou, p. 613]

Information regarding reregistration of pesticide products containing ammonium sulfamate, including how to register under a registration std, regulatory position & rationale, & summaries of data requirements & data gaps is presented. Also, included is a bibliography containing citations of all studies reviewed by the EPA in arriving at the positions & conclusions contained in the standard.[USEPA; Ammonium Sulfamate: Pesticide Registration Standard; Report: 115 pages (1981) Iss EPA-540/RS-81/012; Order No PB82-133570]

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Ammonium sulfamate is found on List A, which contains most food use pesticides and consists of the 194 chemical cases (or 350 individual active ingredients) for which EPA issued registration standards prior to FIFRA '88. Case No: 0016; Pesticide type: herbicide; Registration Standard Date: 4/1/1981; Case Status: No products containing the pesticide are actively registered. Therefore, we are characterizing the case as "cancelled." Under FIFRA, pesticide producers may voluntarily cancel their registered products. EPA also may cancel pesticide registrations if registrants fail to pay required fees or make/meet certain reregistration commitments, or if EPA reaches findings of unreasonable adverse effects.; Active ingredient (AI): ammonium sulfamate; AI Status: The active ingredient is no longer contained in any registered products ... "cancelled.".

Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 15 mg/cu m (total dust)

Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 5 mg/cu m (respirable fraction)

Vacated 1989 OSHA PEL TWA 10 mg/cu m is still enforced in some states. /Total/

Vacated 1989 OSHA PEL TWA 5 mg/cu m is still enforced in some states. /Resp/

Decomposes above 160 °C . This produces ammonia, nitrogen oxides and sulfur oxides. The solution in water is a weak acid. Attacks mild steel. Contact with hot water may cause formation of large amounts of steam. Reacts with acids and strong oxidants.

Fresh air, rest.

Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth.

Excerpt from NIOSH Pocket Guide for Ammonium sulfamate:

(General first aid procedures)

/During fire fighting/ wear goggles and self-contained breathing apparatus.

If material involved in fire, extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn, or burns with difficulty.

Fire Fighting: Any self-contained breathing apparatus with a full facepiece operated in a pressure-demand or other positive pressure mode.

Storage temp: ambient

Rooms used for storage only should be soundly constructed and fitted with secure locks. Floors should be kept clear, and the pesticides clearly identified. /Pesticides/

Environmental considerations - Land spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.

Environmental considerations: Water spill: Add calcium hypochlorite. Adjust pH to neutral (pH 7). Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.

Spillages of pesticides at any stage of their storage or handling should be treated with great care. Liquid formulations may be reduced to solid phase by evaporation. Dry sweeping of solids is always hazardous: these should be removed by vacuum cleaning, or by dissolving them in water, or other solvent in the factory environment. /Pesticides/

Persons not wearing protective equipment and clothing should be restricted from areas of spills until cleanup has been completed. If ammonium sulfamate is spilled, the following steps should be taken: 1. Ventilate area of spill. 2. Collect spilled material in the most convenient and safe manner and deposit in sealed containers. Liquid containing ammonium sulfamate should be absorbed in vermiculite, dry sand, earth, or similar material.

Transfer gradually into a large container of cold water while stirring. After completion of reaction, neutralize with either 3M-HCl or 6M-NH4OH according to the pH of the solution.

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the materials impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Avoid prolonged contact of skin with strong solution. In case of contact, wash off with plenty of water.

If material not on fire and not involved in fire: Keep material out of water sources and sewers. Keep Material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard.

Personnel protection: Avoid breathing vapors. Keep upwind. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. Wear positive pressure self-contained breathing apparatus when fighting fires involving this material.

For more Preventive Measures (Complete) data for AMMONIUM SULFAMATE (7 total), please visit the HSDB record page.

LD50 Quail oral 3000 mg/kg

LC50 Carp (young) 1,000-2,000 mg/L/48 hr /Conditions of bioassay not specified/

LC50 Asellus hilgendorfi (Aquatic sowbug) 3,700 mg/L/24 hr, 3,500 mg/L/48 hr, 2,750 mg/L/96 hr; static

LC50 Oncorrynchus masou (Cherry salmon, yamame trout) 710 mg/L/6 hr, 650 mg/L/12 hr, 24 hr, 48 hr, 96 hr; renewal

For more Ecotoxicity Values (Complete) data for AMMONIUM SULFAMATE (7 total), please visit the HSDB record page.

/BIRDS and MAMMALS/ Deer that were provided ammonium sulfamate in crystalline form or were fed treated foliage of sweet gum, post oak, water oak, persimmon, and black cherry suffered no ill effects from diet.

/BIRDS and MAMMALS/ In 14 days continuous administration to quail in feed, 150 and 590 mg/kg/day produced no change in body weight or any other noticeable changes. Fertility of quail was not affected by 2 periods of 10 days continuous administration of mixed feed containing ammonium sulfamate at rate of 150 mg/kg/day.

Redness. Pain.

irritation eyes, nose, throat; cough, dyspnea (breathing difficulty)

Ammonium sulfamate

2 x 10 ^-1 mg/kg-day

/HUMAN EXPOSURE STUDIES/ Ingestion causes GI disturbances.

/HUMAN EXPOSURE STUDIES/ Ammonium sulfamate is of low toxicity. ...Repeated application of a 4% solution to the anterior surface of one arm of each of 5 human subjects for 5 days caused no skin irritation.

The use of urea-formaldehyde resins as temporary binders in the firing of refractories and ceramics at high temperatures can lead to the formation of substantial deposits of ammonium sulfamate in the cooler parts of kilns, should a fuel oil containing appreciable amount of sulfur be used for firing. Ammonia from decomposition of the resin combines with sulfur trioxide to form ammonium sulfamate which accumulates as either a solidified deposit in flues or as a white deposit on walls. ...

STRAINS OF AUREOBASIDUM (PULLULARIA) PULLULANS, APHALOSPORIUM ACREMONIUM, & 2 UNIDENTIFIED SPECIES OF ACHROMOBACTER & FLAVOBACTERIUM USED SULFAMIC ACID (SODIUM SALT) AS SOURCE OF NITROGEN. BOTH FUNGI & BACTERIA CONVERTED SULFAMATE TO SULFATE IN APPROX EQUIMOLAR PROP TO AMT OF NITROGEN ASSIMILATED.

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Ammonium sulfamate is found on List A, which contains most food use pesticides and consists of the 194 chemical cases (or 350 individual active ingredients) for which EPA issued registration standards prior to FIFRA '88. Case No: 0016; Pesticide type: herbicide; Registration Standard Date: 4/1/1981; Case Status: No products containing the pesticide are actively registered. Therefore, we are characterizing the case as "cancelled." Under FIFRA, pesticide producers may voluntarily cancel their registered products. EPA also may cancel pesticide registrations if registrants fail to pay required fees or make/meet certain reregistration commitments, or if EPA reaches findings of unreasonable adverse effects.; Active ingredient (AI): ammonium sulfamate; AI Status: The active ingredient is no longer contained in any registered products ... "cancelled.".

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 5000 lb or 2270 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

Ammonium sulfamate is designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. This designation includes any isomers and hydrates, as well as any solutions and mixtures containing this substance.

Pesticides used to destroy unwanted vegetation, especially various types of weeds, grasses (POACEAE), and woody plants. Some plants develop HERBICIDE RESISTANCE.

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Used to kill trees, herbaceous perennials, and annual broadleaf weeds; [EXTOXNET]

Du Pont discontinued manufacture in 1988. [EXTOXNET]

Farming (Pesticides) [Category: Industry]

The active ingredient is no longer contained in any registered products ... "cancelled.".

For ammonium sulfamate (USEPA/OPP Pesticide Code: 005501) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

Manufacturer of fire-retardant compositions, for flame-proofing textiles and paper products; manufacture of weed killing compositions; in electroplating solution; for generation of nitrous oxide gas.

(1972) No Data

(1975) No Data

(1972) No Data

(1975) No Data

42% AS A HIGHWAY HERBICIDE; 38% FOR INDUSTRIAL, COMMERCIAL, & INSTITUTIONAL GENERAL MAINTENANCE OF GROUNDS; 10% BY UTILITIES; & 10% IN WATER MANAGEMENT (1972)

(1972) 2.18X10+9 GRAMS (CONSUMPTION)

(1975) 2.04X10+9 GRAMS (CONSUMPTION)

USEPA/OPP Pesticide Code 005501

"Ammate" brand weed killer is brownish-gray crystalline material containing min 80% ammonium sulfamate

Water soluble crystals (Ammate X-NI weed and brush killer)

Ammate X; Ammate X-NI (950 g ai/kg); Amicide, sp (970 g/kg)

For more Formulations/Preparations (Complete) data for AMMONIUM SULFAMATE (15 total), please visit the HSDB record page.

Textiles, apparel, and leather manufacturing

Sulfamic acid, ammonium salt (1:1): ACTIVE

Technical product ... is greater than or equal to 97% pure. ... It forms addition products with aldehydes and is readily oxidized by bromine and chlorine.

Decomposes at 160 °C, the gases acting as a fire retardant. ... It is a non-selective herbicide applied as a foliar spray of aq solution or oil-water emulsion to control woody plants, certain annual and perennial herbaceous weeds. ...

When used in accordance with directions, it is not hazardous to livestock. High rates may cause temporary non-productivity of soil.

Weed killing preparation: Cupery, Tanderg, US Patent 2,277,744 (1941 to Du Pont).