Zinc Phosphate
13847-22-8O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].[Zn+2].[Zn+2].[Zn+2]LRXTYHSAJDENHV-UHFFFAOYSA-HThe CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Phosphate...
13847-22-8、14332-60-6、7779-90-0DTXSID3064807CHEMBL2286756Metals -> Phosphates, Metallic Salts
Metals -> Metals, Inorganic Compounds
Liquid; Other Solid; Dry Powder; Liquid; Liquid; CBI; Wet Solid; Dry Powder
White solid; [Hawley] White odorless powder; [MSDSonline]
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Warning
H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
P273, P391, and P501 (click each P-code to see the statement)
Warning
H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
P273, P391, and P501 (click each P-code to see the statement)
Chemical: Phosphoric acid, zinc salt (2:3)
Chemical: Phosphoric acid, zinc salt
Phosphoric acid, zinc salt (2:3) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, zinc salt (2:3) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Trizinc bis(orthophosphate) (EC: 231-944-3)
Phosphoric acid, zinc salt: Does not have an individual approval but may be used under an appropriate group standard
Powder may cause eye irritation; [MSDSonline] Oral LD50 (rat) >5000 mg/kg; [Ullmann] See Zinc.
See Zinc.
Not Classified
Aquatic Acute 1 (100%)
Hazardous to the aquatic environment (acute) - category 1
Hazardous to the aquatic environment (Acute) - Category 1
Reproductive toxicity - Category 2
Aquatic Acute 1
Zinc can enter the body through the lungs, skin, and gastrointestinal tract. Intestinal absorption of zinc is controlled by zinc carrier protein CRIP. Zinc also binds to metallothioneins, which help prevent absorption of excess zinc. Zinc is widely distributed and found in all tissues and tissues fluids, concentrating in the liver, gastrointestinal tract, kidney, skin, lung, brain, heart, and pancreas. In the bloodstream zinc is found bound to carbonic anhydrase in erythrocytes, as well as bound to albumin, _2-macroglobulin, and amino acids in the the plasma. Albumin and amino acid bound zinc can diffuse across tissue membranes. Zinc is excreted in the urine and faeces. (L49)
CIR ingredient: Zinc Phosphate
Used in dental cements, phosphors, and coatings of steel and aluminum; [Hawley] The most important phosphate-containing pigment--reacts with iron to produce a protective film; [Ullmann]
Aluminum Producing [Category: Industry]
Zinc phosphate is used as a dental cement and corrosion resistant coating. (L74)
Miscellaneous Manufacturing
Phosphoric acid, zinc salt (2:3): ACTIVE
Phosphoric acid, zinc salt (1:?): ACTIVE
Wird geladen…
0.1 [mg/m3] (respirable fraction), 2 mg/m3 (inhalable fraction)-for Zn inorg. compds[German Research Foundation (DFG)]
0.1 [mg/m3] (respirable fraction), 2 mg/m3 (inhalable fraction) for Zn inorg. cmpnds[German Research Foundation (DFG)]
1.8 [mg/m3]
20 [mg/m3]
120 [mg/m3]
The CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Phosphate...
Safe for use in cosmetics, with qualifications
Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49)
Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation. (L49)