Grundinformationen
- CAS
521-74-4- Standard-SMILES
Oc1c(Br)cc(Br)c2cccnc12- InChIKey
ZDASUJMDVPTNTF-UHFFFAOYSA-N- Summenformel
- C9H5Br2NO
- Durchschnittliche Molmasse
- 302,95 g/mol
- Monoisotopische Masse
- 300,87379
Überblick
5,7-dibromo-8-quinolinol is an organohalogen compound and a member of quinolines.
Namen und Bezeichner
- Bevorzugter Name
- Broxyquinoline
- IUPAC
- 5,7-dibromoquinolin-8-ol
- Lokaler Name
- Broxyquinolin
- Englischer Name
- 5,7-Dibromo-8-hydroxyquinoline
- Summenformel
- C9H5Br2NO
- Molmasse
- 302.95
Namen und Synonyme
broxyquinoline5,7-Dibromoquinolin-8-ol521-74-45,7-Dibromo-8-hydroxyquinoline5,7-Dibromo-8-quinolinolDibromoxinBroxyquinolinDibromoxineFenilorDibromoxyquinolineBroxiquinolineBroxykinolin
Weitere Namen anzeigen
PavamibeBromoxinBROMOXINE
DibromoquinBrodiarColepurColipar5,7-DibromooxineDibromoksinParamibaParamibe
Datenbank-Bezeichner
- CAS
521-74-4- PubChem CID
- 2453
- DTXSID
DTXSID9045849- ChEMBL
CHEMBL223448- ChEBI
CHEBI:109543- UNII
- UK4C618C8T
- EC Number
- 208-317-8
- Nikkaji
- J6.615J
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 3,2
- Polarare Oberfläche (TPSA)
- 33,1 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 13
- Formalladung
- 0
- Komplexität
- 190
Experimentelle und physikochemische Eigenschaften
SpringerMaterials PropertiesBoiling point
Collision Cross Section
137.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
136.76 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physikochemische Eigenschaften
- Schmelzpunkt
- 198 · 198-200 °C(lit.)
- Siedepunkt
- 363.74 °C · 363.74°C (rough estimate)
- Dichte
- 2.189 · 2.189
- Brechungsindex
- 1.64 · 1.6400 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Löslichkeit
- DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
- Aggregatzustand
- Solid
- pka
- 2.23 · 2.23±0.30(Predicted)
- Farbe
- Off-White to Pale Beige
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Toxikologische Informationen
Treatment
EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.
Health Effects
Bromine vapour causes irritation and direct damage to the mucous membranes. Elemental bromine also burns the skin. The bromide ion is a central nervous system depressant and chronic exposure produces neuronal effects. This is called bromism and can result in central reactions reaching from somnolence to coma, cachexia, exicosis, loss of reflexes or pathologic reflexes, clonic seizures, tremor, ataxia, loss of neural sensitivity, paresis, papillar edema of the eyes, abnormal speech, cerebral edema, delirium, aggressiveness, and psychoses. (L625, L626, L627)
Exposure Routes
Chemie und Industrie
Pharmakologische Informationen
ATC Code
P - Antiparasitic products, insecticides and repellents
G - Genito urinary system and sex hormones
A - Alimentary tract and metabolism
QA - Alimentary tract and metabolism
QG - Genito urinary system and sex hormones
Metabolism/Metabolites
Bromine is mainly absorbed via inhalation, but may also enter the body through dermal contact. Bromine salts can be ingested. Due to its reactivity, bromine quickly forms bromide and may be deposited in the tissues, displacing other halogens. (L626)
Verwendung und Herstellung
UsesIt is used as an anti-infective. Diatomic bromine does not occur naturally, but bromine salts can be found in crustal rock.
General Manufacturing Information8-Quinolinol, 5,7-dibromo-: INACTIVE
Anwendungen
Verwendenantiinfectant, disinfectant
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Nachgelagerte Produkte
Zugehörige Reaktionen
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