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Chromtrinitrat
CHROMIUM NITRATE · CHROMIUM(III) NITRATE · CHROMIC NITRATE NONAHYDRATE · chromium(iii) nitrate solution · CHROMIUM(III) NITRATE NONAHYDRATE · CHROMIC NITRATE · Chromium trinitrate · CHROMIC NITRATE 9H2O
Identifikatoren & physikalische Daten
| CAS No. | 13548-38-4 |
|---|---|
| Summenformel | CrN3O9 |
| Durchschnittliche Molmasse | 238,01 g/mol |
| Monoisotopische Masse | 237,90396108 g/mol |
| SMILES | O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].[Cr+3] |
| InChIKey | PHFQLYPOURZARY-UHFFFAOYSA-N |
| PubChem CID | 24598 |
| ChEBI | CHEBI:86204 |
| EC No. | 236-921-1 |
| DTXSID | DTXSID8065531 |
| Lokaler Name | Chromtrinitrat |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 189 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 9 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 13 |
| Formalladung | 0 |
| Komplexität | 18,8 |
| Stoffklassen | Metals -> Chromium Compounds, Inorganic |
| Physical Description | LiquidOther SolidLarge CrystalsPale green solidExtremely deliquescentSoluble in water[Merck Index] |
| Schmelzpunkt | 60 °C(lit.) |
| Dichte | 1.00 g/mL at 20 °C |
| Dampfdruck | 1Pa at 20℃ |
| Löslichkeit | very soluble in H2O |
| Aggregatzustand | Crystalline Chunks |
| Farbe | Dark purple to black |
| Merck | 13,2246 |
| InChI | InChI=1S/Cr/q+3 |
| InChIKey | BFGKITSFLPAWGI-UHFFFAOYSA-N |
| SMILES | [Cr+3] |
| LogP (Verteilungskoeffizient) | -3 at 20℃ |
| CAS Datenbank | 13548-38-4(CAS DataBase Reference) |
| EPA chemische Informationen | Chromium(III) nitrate (13548-38-4) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 13.8% (41 of 297) of reports.DangerH272 (76.8%): May intensify fireoxidizer [Danger Oxidizing liquidsOxidizing solids]P210, P220, P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 297 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Nitric acid, chromium(3+) saltNitric acid, chromium(3+) salt (3:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Nitric acid, chromium(3+) salt (3:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 13-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13746Nitric acid, chromium(3+) salt: HSNO Approval: HSR001320 Approved with controls |
| Gefahrenübersicht | Chromium (III) nitrate normally crystallizes with 9 molecules of water[Ullmann] A strong oxidizing agentMay cause fire on contact with organic materialMay cause irritation to skin, eyes, and mucous membranes[CAMEO] May cause skin and respiratory sensitization after prolonged contact[eChemPortal: ERMA] See Chromium III nitrate nonahydrate. See NITRATES and NITRITES. See Cr(III) compounds in Chromium. |
| Hazard Classes and Categories | Ox. Sol. 3 (76.8%) |
| Threshold Limit Values (TLV) | 0.003 [mg/m3], as Cr(III), inhalable particulate matter |
| Permissible Exposure Limit (PEL) | 0.5 [mg/m3] |
| Protective Action Criteria (PAC) | 0.041 [mg/m3]110 [mg/m3]640 [mg/m3] |
| Treatment | There is no know antidote for chromium poisoning. Exposure is usually handled with symptomatic treatment. Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution administered intravenously slowly over five minutes followed by IV flush with normal saline. Methylene blue restores the iron in hemoglobin to its normal (reduced) oxygen-carrying state. (L1613, L16) |
| Gesundheitliche Auswirkungen | Chromium in its trivalent state is not very toxic. It may be oxidized to hexavalent chromium, a known carcinogen. Hexavalent chromium has also been shown to affect reproduction and development. Nitrate and nitrite poisoning causes methemoglobinemia. Nitrites may cause pregnancy complications and developmental effects. They may also be carcinogenic. (L1137, A12) |
| Unerwünschte Wirkungen | Methemoglobinemia - The presence of increased methemoglobin in the bloodthe compound is classified as secondary toxic effect |
| Expositionspfade | Oral (L16)inhalation (L16)dermal (L16) |
| Toxizitätsübersicht | Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, chromium-DNA adducts, chromosomal aberrations and alterations in cellular signaling pathways. It has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated protein kinases. It can also cause transcriptional repression by cross-linking histone deacetylase 1-DNA methyltransferase 1 complexes to CYP1A1 promoter chromatin, inhibiting histone modification. Chromium may increase its own toxicity by modifying metal regulatory transcription factor 1, causing the inhibition of zinc-induced metallothionein transcription. Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as methemoglobinemia, and is characterized by tissue hypoxia, as methemoglobin cannot bind oxygen. (A2450, L1613, A12, L16, A34, A35, A36) |
| Signs and Symptoms | Chromium in its trivalent state is not very toxic, but it may be oxidized to hexavalent chromium. Breathing hexavalent chromium can cause irritation to the lining of the nose, nose ulcers, runny nose, and breathing problems, such as asthma, cough, shortness of breath, or wheezing. Ingestion of hexavalent chromium causes irritation and ulcers in the stomach and small intestine, as well as anemia. Skin contact can cause skin ulcers. Nitrate and nitrite poisoning causes methemoglobinemia. Symptoms include cyanosis, cardiac dysrhythmias and circulatory failure, and progressive central nervous system (CNS) effects. CNS effects can range from mild dizziness and lethargy to coma and convulsions. (L1137, L16) |
| Carcinogen Classification | Ingested nitrate or nitrite under conditions that result in endogenous nitrosation is probably carcinogenic to humans (Group 2A). Chromium (III) compounds are not classifiable as to their carcinogenicity to humans (Group 3). (L135) |
| Toxicity Data | LD50: 3250 mg/kg (Oral, Rat) (L533) |
| F | 9 |
| Wassergefährdungsklasse (WGK) | 2 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 2720 (CHROMIUM NITRATE) |
| Zollcode | 2834298000 |
| RTECS-Nr. | GB6300000 |
| R-Sätze (R) | 8-36/38-34-20-37-35 |
| Toxizität | mouse,LD50,intraperitoneal,110mg/kg (110mg/kg),Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 20, Pg. 590, 1978. |
| Gefahrensymbole | O,Xi,C |
| Sicherheitshinweise (S) | 17-26-36-45-36/37/39-23 |
| Gefahrenklasse | 5.1 |
| Verpackungsgruppe | III |
Anwendungen & Verwendung
Verwenden
Catalyst, corrosion inhibitor.