7789-30-2XHVUVQAANZKEKF-UHFFFAOYSA-NBromine pentafluoride appears as a colorless, fuming liquid with a pungent odor. Used to make other chemicals and in rockets. Very toxic by inhalation. Corrosive to metals and tissue. Will accelerate the burning of combustible material. If the containers are involved in a fire they may rupture violently and rocket.
7789-30-2DTXSID30894171CHEBI:193148Toxic Gases & Vapors -> Oxidizers
Corrosives
2.48 at 68 °F (USCG, 1999) - Denser than water; will sink
2.4604 g/cu cm at 25 °C
Relative density (water = 1): 2.5
2.48
2.466 @25 °C
2.48
Liquid
Colorless fuming liquid
Reacts with water violently (NIOSH, 2024)
Produces an explosion on contact with water
Solubility in water: reaction
Reacts violently
106 °F at 760 mmHg (USCG, 1999)
40.76 °C
41 °C
105 °F
40.5 °C @760 [mm Hg]
105 °F
-76 °F (USCG, 1999)
-60.5 °C
-61 °C
-77 °F
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Danger
H271: May cause fire or explosion; strong Oxidizer [Danger Oxidizing liquids; Oxidizing solids]
P210, P220, P260, P264, P264+P265, P270, P271, P280, P283, P284, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P306+P360, P308+P316, P316, P317, P319, P320, P321, P331, P363, P370+P378, P371+P380+P375, P403+P233, P405, P420, and P501 (click each P-code to see the statement)
Bromine fluoride (BrF5): Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
Special Hazards of Combustion Products: Toxic and irritating fumes of hydrogen fluoride and bromine may form in fires.
· May ignite combustibles (wood, paper, oil, clothing, etc.).
Not combustible but enhances combustion of other substances. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire. Risk of fire and explosion on contact with water, steam, fuels or organic materials.
The mechanism by which halogen fluorides exert their acute toxicity is by direct irritation and corrosion. In experimental animals, these strong oxidizing chemicals produce lacrimation, sneezing, and salivation, which progresses to nausea, difficult respiration, and unconsciousness with cyanosis. Lacrimation and rhinorrhea are responses to stimulation of the trigeminal nerve. The eyes and exposed skin suffer burns. At the high concentrations that cause lethality, the capacity of the upper respiratory tract to scrub the halogen fluorides from the inhaled air is exceeded, and the chemicals penetrate to the lungs, causing edema and destruction of the pulmonary tissue. These signs were observed in monkeys, dogs, rats, and mice exposed to ClF5 and in rats exposed to BrF5.
...the halogen fluorides are expected to hydrolyze rapidly in the moist respiratory tract. /Halogen fluorides/
Bromine is mainly absorbed via inhalation, but may also enter the body through dermal contact. Bromine salts can be ingested. Due to its reactivity, bromine quickly forms bromide and may be deposited in the tissues, displacing other halogens. (L626)
/Investigators/ measured fluoride in rat tissues following exposure to BrF5 at 500 ppm for 30 min or ClF3 at 400 ppm for 15 min... The data show increased fluoride content in the blood and lungs immediately after exposure, which declined over time. Mean fluoride in bone increased from 300 ug/g immediately after exposure to BrF5 to 353 ug/g 20 hr later. After exposure to ClF3, mean fluoride in bone increased from 118 to 172 ug/g over a 24-hr period. Although a small number of animals (four to six) are represented by the mean values and fluoride concentrations in untreated rats varied widely, the data suggest that, at higher concentrations of halogen fluorides, fluoride may be absorbed into the bloodstream and distributed to bone and other tissues.
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Wird geladen…
-60.5 °C
-77 °F
6.05 (Air = 1)
Relative vapor density (air = 1): 6.1
328 mmHg (NIOSH, 2024)
406.0 [mmHg]
406 mm Hg at 25 °C
Vapor pressure, kPa at 20 °C: 44
328 mmHg
328 [mm Hg] @20 °C
Bromine pentafluoride appears as a colorless, fuming liquid with a pungent odor. Used to make other chemicals and in rockets. Very toxic by inhalation. Corrosive to metals and tissue. Will accelerate the burning of combustible material. If the containers are involved in a fire they may rupture violently and rocket.
Colorless to pale-yellow, fuming liquid with a pungent odor; Note: A colorless gas above 105 degrees F. Shipped as a compressed gas; [NIOSH]
PALE YELLOW OR COLOURLESS FUMING LIQUID WITH PUNGENT ODOUR.
Colorless to pale-yellow, fuming liquid with a pungent odor.
Colorless to pale-yellow, fuming liquid with a pungent odor. [Note: A colorless gas above 105 °F. Shipped as a compressed gas.]
Chemical is highly corrosive and toxic. Inhalation causes severe burns of mucous membrane. Ingestion causes severe burns of mouth. Contact with eyes or skin causes severe burns. (USCG, 1999)
· TOXIC; inhalation or contact with vapor, substance, or decomposition products may cause severe injury or death.
Skin or eye contact can cause painful, deep-seated, long-lasting burns. In animal studies, bromine trifluoride produces elevated fluoride levels and severe lung irritation and pneumonitis; [ACGIH] Animals exposed chronically to > 3 ppm have liver, kidney, and respiratory injury; [HSDB] A corrosive substance that can cause pulmonary edema; May cause fluorosis; [ICSC] See FLUORIDES.
1745 144
1745 144
Excerpt from ERG Guide 144 [Oxidizers (Water-Reactive)]:
In case of fire in the surroundings, use appropriate extinguishing media. NO hydrous agents. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. Combat fire from a sheltered position.
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Wear protective gloves when administering first aid. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Do NOT induce vomiting. Refer for medical attention .
· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.
· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
Excerpt from NIOSH Pocket Guide for Bromine pentafluoride:
General First Aid:
(General first aid procedures)
· Wear positive pressure self-contained breathing apparatus (SCBA).
TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016].
If material involved in fire: Do not use water on material itself. Use dry chemical or carbon dioxide. Cool all affected containers with flooding quantities of water. If large quantities of combustibles are involved, use water in flooding quantities as spray and fog. Use water spray to knock-down vapors.
Evacuation: If fire becomes uncontrollable or container is exposed to direct flame-consider evacuation of one-third (1/3) mile radius. If material leaking (not on fire) consider evacuation form downwind area based on amount of material spilled, location and weather conditions.
... Use appropriate extinguishing agents on nearby fires. Use dry chemical, dry sand, or carbon dioxide. Use water spray to keep fire-exposed containers cool.
SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.
SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.
EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.
Bromine vapour causes irritation and direct damage to the mucous membranes. Elemental bromine also burns the skin. The bromide ion is a central nervous system depressant and chronic exposure produces neuronal effects. This is called bromism and can result in central reactions reaching from somnolence to coma, cachexia, exicosis, loss of reflexes or pathologic reflexes, clonic seizures, tremor, ataxia, loss of neural sensitivity, paresis, papillar edema of the eyes, abnormal speech, cerebral edema, delirium, aggressiveness, and psychoses. (L625, L626, L627)
TERRESTRIAL FATE: Bromine pentafluoride decomposes, sometimes explosively, on contact with water(1) and hydrogen-containing materials(2).
AQUATIC FATE: Bromine pentafluoride decomposes, sometimes explosively, on contact with water to yield hydrofluoric acid and other materials(1).
ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), bromine pentafluoride, which has a vapor pressure of 406 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Bromine pentafluoride is a relatively heavy vapor with a vapor density 6.05 times that of air(3). Bromine pentafluoride explodes and decomposes on contact with water to yield hydrofluoric acid and other materials(4). It fumes in air(5), reacts with steam, and decomposes on contact with hydrogen-containing materials(3).
The substance can be absorbed into the body by inhalation of its vapour.
inhalation, ingestion, skin and/or eye contact
Oral (L626) ; inhalation (L626) ; dermal (L626)
IDENTIFICATION AND USE: Bromine pentafluoride (BrF5) is a liquid with a sharp penetrating odor. BrF5 is predominantly used as a fluorinating agent to produce fluorocarbons and as an oxidizer in rocket propellant systems. Metal chlorides, bromides, and iodides are converted to fluorides by treatment with BrF5. Uranium is converted to uranium hexafluoride by strong oxidizing agents, including BrF5. HUMAN EXPOSURE AND TOXICITY: Acute exposure to BrF5 can cause redness and tearing of the eyes, coughing, breathing difficulty, and a burning sensation of the eyes, nose, and throat. Direct contact of this substance with the eyes or skin can cause severe thermal and chemical burns and tissue destruction. The acute effect of this substance on the lung is similar to that of phosgene. Individuals with asthma may respond to exposure to respiratory irritants with increased bronchial responsiveness. The elderly and those who are ill may also have increased susceptibility to the effects of irritants. Individuals under stress, such as those involved in emergency situations and individuals engaged in physical activity, will experience greater deposition and pulmonary irritation than individuals at rest. Furthermore, individuals who breathe through their mouths would be at greater risk. ANIMAL STUDIES: BrF5 has been shown to be acutely toxic in animals. Animals exposed to bromine pentafluoride vapor at 500 ppm exhibited immediate symptoms of gasping, swollen eyelids, clouded corneas, tearing, salivation, and acute distress; these symptoms appeared after exposure for a period as short as three minutes. Exposures to 50 ppm were fatal after 30 minutes, and chronic exposures above 3 ppm resulted in severe nephrosis (in some animals), as well as marked hepatosis and severe respiratory involvement.
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and produce tissue damage. In additon, the formation of hydrobromic and bromic acids will result in secondary irritation. The bromide ion is also known to affect the central nervous system, causing bromism. This is believed to be a result of bromide ions substituting for chloride ions in the in actions of neurotransmitters and transport systems, thus affecting numerous synaptic processes. (L626, L627, A543)
Burning sensation. Cough. Shortness of breath. Sore throat. Laboured breathing. Symptoms may be delayed.
Redness. Pain. Skin burns. Blisters.
Redness. Pain. Blurred vision. Severe deep burns.
Abdominal pain. Burning sensation. Shock or collapse.
irritation eyes, skin, respiratory system; corneal necrosis; skin burns; cough, dyspnea (breathing difficulty), pulmonary edema; liver, kidney injury
Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways, coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous system depressant producing ataxia, slurred speech, tremor, nausea, vomiting, lethargy, dizziness, visual disturbances, unsteadiness, headaches, impaired memory and concentration, disorientation and hallucinations. This is called bromism. (L626, L627)
Preplacement medical evaluation: Before a worker is placed in a job with a potential for exposure to bromine pentafluoride, a licensed health care professional should evaluate and document the worker's baseline heath status with thorough medical, environmental, and occupational histories, a physical examination, and physiologic and laboratory tests appropriate for the anticipated occupational risks. These should concentrate on the function and integrity of the liver, kidneys, and lungs.
Periodic medical examinations and biological monitoring: Occupational health interviews and physical examinations should be performed at regular intervals ... Additional examinations may be necessary if a worker develops symptoms attributable to bromine pentafluoride exposure. The interviews, examinations, and medical screening tests should focus on identifying the adverse effects of bromine pentafluoride on the liver, kidneys, and lungs... No biological monitoring test acceptable for routine use has yet been developed for bromine pentafluoride.
Bromine pentafluoride decomposes, sometimes explosively, on contact with water(1). It also explodes or ignites on contact with hydrogen-containing materials (e.g. acetic acid, ammonia, benzene, ethanol, hydrogen, hydrogen sulfide, methane cork, grease, paper, wax)(2).
/SIGNS AND SYMPTOMS/ Acute exposure to bromine pentafluoride can cause redness and tearing of the eyes, coughing, breathing difficulty, and a burning sensation of the eyes, nose, and throat. Direct contact of this substance with the eyes or skin can cause severe thermal and chemical burns and tissue destruction.
/SIGNS AND SYMPTOMS/ Skin or eye contact with vapor or liquid bromine pentafluoride causes painful, deep-seated, long-lasting burns. ...
/OTHER TOXICITY INFORMATION/ ...use of BrF5 and BrF3 in the synthesis of uranium hexafluoride suggests the possibility of coexposure to bromine and uranium fluorides in the context of accidental releases. As HF is a hydrolysis product of both the bromine fluorides and uranium hexafluoride, coexposure to these compounds might lead to greater toxicity due to higher levels of the reaction product HF.
Bromine pentafluoride
A Commercial Grade
A Placarded Amount
Chemical or material that can be mixed with readily available materials.
Used to produce fluorocarbons and as an oxidizer in rocket fuels; [ACGIH]
Toxic Gas from Spilling Chemical in Water [Category: Other]
Synthesis, oxidizer in liquid rocket propellants.
BrF5 is predominantly used as a fluorinating agent to produce fluorocarbons and as an oxidizer in rocket propellant systems. Metal chlorides, bromides, and iodides are converted to fluorides by treatment with BrF5. Uranium is converted to uranium hexafluoride by strong oxidizing agents, including BrF5.
A technique has been developed in which bromine pentafluoride is used as a reagent for quantitative liberation of oxygen from oxides and silicates. For all of the rocks and minerals analyzed, the oxygen yields are 100 +/- 2 per cent of the theoretical amount. The advantage over techniques involving reduction with carbon lies in the consistently better oxygen yields, with consequent decrease in systematic errors in isotopic composition. Bromine pentafluoride has advantages over fluorine in being easier and safer to handle in the laboratory, in being readily purified, and in reacting with some minerals which do not react completely with fluorine. The results of isotopic analyses are compared with measurements made in other laboratories by other procedures.
Used as a fluorinating agent in uranium processing and as the oxidizer component of some rocket propellants.
Prepd by fluorination of bromine at 200 °C in iron or Monel metal apparatus.
By reacting bromine, diluted with nitrogen and fluorine, in a copper vessel at 200 °C.
BrF5 is manufactured by the fluorination of bromine at 200 °C in a metal apparatus. It can also be prepared by heating a mixture of BrF3 and fluorine to 200 °C.
Bromine pentafluoride can be formed either by (1) the direct reaction of bromine with excess fluorine above 150 °C or by (2) the reaction of BrF3 vapor and gaseous fluorine at 200 °C.
VerwendenBromine pentafluoride (BrF5) is very corrosive to the skin and explodes when in contact with water. It is used as an oxidizer in rocket fuel.
synthetischeBromine pentafluoride is prepared by fluorination of bromine at 200°C. The reaction is carried out in an iron or copper vessel. The halogens are diluted in nitrogen.