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Cobaltous chloride hexahydrate
COCl · COBALT(II) CHLORIDE HEXAHYDRATE · COBALTOUS CHLORIDE HEXAHYDRATE · cobalt chloride hydrate · COBALTOUS CHLORIDE · chlorekcobaltawy · Cobalt chlordie · CobaltousChlorideAr
Identifikatoren & physikalische Daten
| CAS No. | 7791-13-1 |
|---|---|
| Summenformel | Cl2Co.6H2O |
| Durchschnittliche Molmasse | 237,93 g/mol |
| Monoisotopische Masse | 236,934287 g/mol |
| SMILES | O.O.O.O.O.O.[Cl-].[Cl-].[Co+2] |
| InChIKey | GFHNAMRJFCEERV-UHFFFAOYSA-L |
| PubChem CID | 24643 |
| ChEBI | CHEBI:53503 |
| EC No. | 616-574-6 |
| DTXSID | DTXSID20999109 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 6 |
|---|---|
| H-Brücken-Donoren | 6 |
| H-Brücken-Akzeptoren | 8 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 9 |
| Formalladung | 0 |
| Komplexität | 0 |
| Dichte | 1.924 @25 °C3.35 |
| Siedepunkt | 1049 °C @760 [mm Hg] |
| Schmelzpunkt | 86 °C |
| Physical Description | Liquid |
| Dampfdruck | 40 mm Hg ( 0 °C) |
| Lagerbedingungen | Store at +5°C to +30°C. |
| Löslichkeit | 191g/lSoluble in water, ether, acetone and alcohol. |
| Aggregatzustand | Solid |
| Farbe | Red-purple |
| Wichte | 1.924 |
| pH | 4.9 (50g/l, H2O, 25℃) |
| Geruch | at 100.00%. odorless |
| Merck | 14,2437 |
| Stabilität | Hygroscopic |
| InChI | 1S/2ClH.Co.6H2O/h2*1H6*1H2/q+2/p-2 |
| InChIKey | GFHNAMRJFCEERV-UHFFFAOYSA-L |
| SMILES | O.O.O.O.O.O.Cl[Co]Cl |
| LogP (Verteilungskoeffizient) | -1.380 (est) |
| CAS Datenbank | 7791-13-1(CAS DataBase Reference) |
| EPA chemische Informationen | Cobalt chloride (CoCl2), hexahydrate (7791-13-1) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH302+H332 (17.5%): Harmful if swallowed or if inhaled [Warning Acute toxicity, oralacute toxicity, inhalation]P203, P233, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P318, P321, P330, P333+P317, P342+P316, P362+P364, P391, P403, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 126 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H302: Harmful if swallowed [Warning Acute toxicity, oral] |
|---|---|
| Regulatorische Informationen | Chemical: Cobalt(II) chloride, hexahydrateDirective (EC) No 46/2002Cobalt chloride (CoCl2), hexahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Cobalt chloride (CoCl2), hexahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Cobalt (II) chloride: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | PEC / SN / Other assessments - Common skin sensitisersâhazard classification: Health |
| Hazard Classes and Categories | Acute Tox. 4 (99.2%)Acute toxicity - category 4 |
| Protective Action Criteria (PAC) | 0.24 [mg/m3]26 [mg/m3]150 [mg/m3] |
| Wassergefährdungsklasse (WGK) | 2 |
| TSCA-Inventar-Status | Yes |
| UN-Transportnummer | UN 3260 8/PG 2 |
| Zollcode | 28273400 |
| RTECS-Nr. | GG0200000 |
| R-Sätze (R) | 49-22-42/43-50/53-68-60 |
| Toxizität |
Anwendungen & Verwendung
Verwenden
Cobalt(II) chloride hexahydrate (CoCl2·6H2O) has been found to be an efficient catalyst for the one-pot synthesis of biscoumarin derivatives through a combination of aromatic aldehydes and 4-hydroxycoumarin in aqueous media at 70°C. Cobalt chloride hexahydrate can be used as an inducer of HIF-1 production used to study apoptotic effects in HepG2 cells. It is also used as APHA color standard.