2-Hydroxyethylstearat
Glycol monostearate
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
111-60-4- Standard-SMILES
CCCCCCCCCCCCCCCCCC(=O)OCCO- InChIKey
RFVNOJDQRGSOEL-UHFFFAOYSA-N- Summenformel
- C20H40O3
- Durchschnittliche Molmasse
- 328,5 g/mol
- Monoisotopische Masse
- 328,29774513
Überblick
Polyoxyl 40 stearate is an octadecanoate ester composed of repeating 8-40 ethyleneoxy units. It is an ingredient used in cosmetics and beauty products primarily as a surfactant and emulsifier. It has a role as a nonionic surfactant, an emulsifier and a food emulsifier. It is a hydroxypolyether and an octadecanoate ester.
Namen und Bezeichner
- Bevorzugter Name
- Glycol monostearate
- IUPAC
- 2-hydroxyethyl octadecanoate
- Lokaler Name
- 2-Hydroxyethylstearat
- Englischer Name
- ETHYLENE GLYCOL MONOSTEARATE
- Summenformel
- C20H40O3
- Molmasse
- 328.53
Namen und Synonyme
Ethylene glycol monostearateGlycol stearate111-60-42-Hydroxyethyl octadecanoateMonthybaseParastarinMonthyleSedetolIvoritGlycol monostearateProdhybase ethylProdhybas N
Weitere Namen anzeigen
s151FGMSS 151lipoegms
Clindrol SEGEmerest 2350Ethylene glycol stearateLipo EGMSEmpilan 2848OCTADECANOIC ACID, 2-HYDROXYETHYL ESTERUSAF KE-11STEARIC ACID, 2-HYDROXYETHYL ESTER
Datenbank-Bezeichner
- CAS
111-60-4、86418-55-5、9004-99-3- PubChem CID
- 24762
- DTXSID
DTXSID5026881- ChEMBL
CHEMBL2355383- ChEBI
CHEBI:32027- UNII
- 0324G66D0E
- EC Number
- 203-886-9、617-851-4、618-405-1、926-608-4
- Nikkaji
- J110.879D
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- XLogP
- 7,8
- Polarare Oberfläche (TPSA)
- 46,5 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 19
- Schwere Atome
- 23
- Formalladung
- 0
- Komplexität
- 241
Experimentelle und physikochemische Eigenschaften
PolymersOther Classes -> Polyoxyethylenes
Cosmetics
Cosmetic ingredients (Glycol Stearate) -> CIR (Cosmetic Ingredient Review)
Cosmetic ingredients (Glycol Stearate SE) -> CIR (Cosmetic Ingredient Review)
Surfactant; Opacifying; Emollient; Emulsifying; Humectant
OdorFAINT FATTY ODOR
TasteSLIGHTLY BITTER, FATTY TASTE
Color/FormCREAM-COLORED SOFT, WAXY OR PASTY SOLID @ 25 °C
Solubility
POLYETHYLENE GLYCOL ESTERS AND ETHERS INCR THE WATER SOLUBILITY OF TYROTHRICIN.
SOL IN CARBON TETRACHLORIDE, PETROLEUM BENZIN, CHLOROFORM, ETHER; SLIGHTLY SOL IN ALCOHOL; INSOL IN WATER /POLYETHYLENE GLYCOL 400 MONOSTEARATE USP XVI/
GENERALLY SOL OR DISPERSIBLE IN WATER
SOL IN TOLUENE, ACETONE, ETHER AND ETHANOL
Flash PointMYRJ 45: 500 °F OC
Melting Point
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 75.2% (357 of 475) of all reports.
Warning
H315 (18.9%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 475 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
This chemical does not meet GHS hazard criteria for 87% (267 of 307) of all reports.
Gefahrenhinweise
Regulatory Information
Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy-
Chemical: Octadecanoic acid, 2-hydroxyethyl ester
Octadecanoic acid, 2-hydroxyethyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, 2-hydroxyethyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
FRI - indicates a polymeric substance containing no free-radical initiator in its Inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used.
Octadecanoic acid, 2-hydroxyethyl ester: Does not have an individual approval but may be used under an appropriate group standard
Tegin G: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Caused bladder stones in rats when fed at >20% of diet; [JECFA] Mild irritant effect in eye of rabbit; [RTECS] Hydrolyzed in the intestines--fatty acids metabolized and the polyoxyethylene residues excreted unchanged in the urine; [HSDB] An irritant; [MSDSonline] See STEARATES.
Chemie und Industrie
Pharmakologische Informationen
Absorption, Distribution and Excretion
THESE ESTERS ARE HYDROLYZED IN THE BOWEL. THE FATTY ACID IS ABSORBED & METABOLIZED; AT LEAST THE SHORTER POLYOXYETHYLENE RESIDUES ARE ALSO ABSORBED, BUT THEY ARE EXCRETED UNCHANGED IN THE URINE (NO DETECTABLE METABOLISM TO OXALIC ACID IN MAN).
Cellular LocationsExtracellular
Verwendung und Herstellung
Uses
CIR ingredient: Glycol Stearate
CIR ingredient: Glycol Stearate SE
Used as a surfactant, emulsifier (cosmetics, pharmaceuticals, textile finishes, defoamers, and baked goods), dye assistant, lubricant, and antistatic agent; Also used in dentifrice compositions and to make creams, lotions, ointments, and pharmaceutical preparations; [HSDB]
Textiles (Printing, Dyeing, or Finishing) [Category: Industry]
SURFACTANT
PEG 400 MONOSTEARATE USP XVI: IN PREPN OF CREAMS, LOTIONS, OINTMENTS & PHARMACEUTICAL PREPN WHICH ARE SOL IN WATER
U.S. Production
2023: 1,000,000 - <2,500,000 lb
(1972) 2.4X10+9 GRAMS (MONOSTEARATE)
(1975) 3.13X10+9 GRAMS (MONOSTEARATES)
(1984) 2.91X10+9 g
Consumer UsesSurfactant (surface active agent)
Industry UsesSurfactant (surface active agent)
Methods of ManufacturingREACTION OF ETHYLENE OXIDE WITH STEARIC ACID
Formulations/PreparationsPOLYOXYETHYLENE (8) STEARATE: MIXTURE OF MONO- & DIESTERS OF STEARIC ACID & MIXED POLYOXYETHYLENE DIOLS HAVING AN AVG POLYMER LENGTH OF 7.5 OXYETHYLENE UNITS.
Zugehörige Reaktionen
1
Notizen zur Verbindung
Wird geladen…