3-Hydroxy-5-methylisoxazol

Hymexazol

HCID 24781CAS 10004-44-1
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Grundinformationen

Standard-SMILES
Cc1cc(=O)[nH]o1
InChIKey
KGVPNLBXJKTABS-UHFFFAOYSA-N
Summenformel
C4H5NO2
Durchschnittliche Molmasse
99,089 g/mol
Monoisotopische Masse
99,0320284

Namen und Bezeichner

Bevorzugter Name
Hymexazol
IUPAC
5-Methyl-1,2-oxazol-3(2H)-one
Lokaler Name
3-Hydroxy-5-methylisoxazol
Englischer Name
Hymexazol
Summenformel
C4H5NO2
Molmasse
99.09

Namen und Synonyme

HYMEXAZOLE5-METHYLISOXAZOL-3-OL5-Methylisoxazol-3(2H)-one3-HYDROXY-5-METHYLISOXAZOLETACHIGALOZEHYDROXYISOXAZOLE5-Hydroxy-3-methylisoxazolebucidf-319T 319

Datenbank-Bezeichner

CAS
10004-44-1
PubChem CID
24781
DTXSID
DTXSID3032622
ChEMBL
CHEMBL244877
ChEBI
CHEBI:5827
UNII
20T2M875LO
EC Number
233-000-6
Nikkaji
J3.115A

Eigenschaften

Berechnete Struktureigenschaften

XLogP
0,1
Polarare Oberfläche (TPSA)
38,3 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
0
Schwere Atome
7

Physikochemische Eigenschaften

Schmelzpunkt
80 °C · 80°C
Siedepunkt
185.54 °C · 185.54°C (rough estimate)
Dichte
1.2992 · 1.2992 (rough estimate)
Dampfdruck
0.182 Pa · 0.182 Pa (25 °C)
Brechungsindex
1.417 · 1.4170 (estimate)
storage temp.
2 · 2-8°C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]；H317: May cause an allergic skin reaction [Warning Sensitization, Skin]；H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]；H361d: Suspected of damaging the unborn child [Warning Reproductive toxicity]；H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P203, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P318, P321, P330, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)

Danger

Gefahrenhinweise

Regulatory Information · 4 Einträge

Commission Regulation (EC) No 1490/2002

Hymexazol is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)

2011/5/EU, Reg. (EU) 2023/918, Reg.(EU) No 2018/1266, Reg.(EU) No 540/2011

Hymexazol: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - 3(2H)-Isoxazolone, 5-methyl-: Human health tier I assessment；IMAP assessments - 3(2H)-Isoxazolone, 5-methyl-: Environment tier I assessment
Hazard Classes and Categories · 3 Einträge

Acute Tox. 4 (100%)；Skin Sens. 1 (47.7%)；Eye Dam. 1 (98.9%)；Repr. 2 (14.8%)；Repr. 2 (33%)；Aquatic Chronic 2 (47.7%)；Aquatic Chronic 3 (51.1%)

Reproductive toxicity - category 2；Acute toxicity (ingestion) - category 4；Eye damage - category 1；Skin sensitisation - category 1；Hazardous to the aquatic environment (chronic) - category 2

Repr. 2；Acute Tox. 4；Eye Dam. 1；Skin Sens. 1；Aquatic Chronic 2

Toxikologische Informationen

RAIS Toxicity Values · 4 Einträge

1.5

OPP

0.3

OPP

EPA Human Health Benchmarks for Pesticides · 6 Einträge

Hymexazol

1.5

10000

Children

0.3

2000

Regulatorische Informationen

Regulatory Information · 4 Einträge

Commission Regulation (EC) No 1490/2002

Hymexazol is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)

2011/5/EU, Reg. (EU) 2023/918, Reg.(EU) No 2018/1266, Reg.(EU) No 540/2011

Hymexazol: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

wgk
3
hs_code
29349990
RTECS-Nr.
NY2932000
risk_code
22-41-52/53
Toxizität
LD50 in male, female mice, rats (mg/kg): 2148, 1968, 4678, 3909 orally; 1297, 1167, 1924, 1884 s.c.; 445, 514, >1000, >1000 i.v.; in rats, rabbits (mg/kg): >10000, >2000 dermally (Nakamura, 1978)
hazard_code
Xn,Xi

Chemie und Industrie

Verwendung und Herstellung

Use ClassificationEnvironmental transformation -> Pesticides (parent, predecessor)
Anwendungen · 1 Eintrag

VerwendenHymexazol is used to control soil-borne diseases caused by Fusarium, Aphanomyces, Pythium, Corficium and Typhula spp. in rice, sugar beet, fodder beet, vegetables, cucurbits, ornamentals, carnations and forest tree seedlings. It is also used as a seed dressing and stimulates some plant growth.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: A member of the class of isoxazoles carrying hydroxy and methyl substituents at positions 3 and 5 respectively. It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces Pythium, and Corticium spp. in rice, sugarbeet, fodderbeet, vegetables, cucurbits, and ornamentals.

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