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Diammoniumeisenbis(sulfat)
FERROUS AMMONIUM SULPHATE · FERROUS AMMONIUM SULFATE · AMMONIUM FERROUS SULPHATE · MOHR SALT · AMMONIUM FERROUS SULFATE · NA-9122 · ACS,98.5-102.0% · ammoniumironsulfate
Identifikatoren & physikalische Daten
| CAS No. | 10045-89-3 |
|---|---|
| Summenformel | FeH8N2O8S2 |
| Durchschnittliche Molmasse | 284,1 g/mol |
| Monoisotopische Masse | 283,90714472 g/mol |
| SMILES | O=S(=O)([O-])[O-].O=S(=O)([O-])[O-].[Fe+2].[NH4+].[NH4+] |
| InChIKey | IMBKASBLAKCLEM-UHFFFAOYSA-L |
| PubChem CID | 24863 |
| ChEBI | CHEBI:76243 |
| EC No. | 233-151-8 |
| DTXSID | DTXSID4041028 |
| Lokaler Name | Diammoniumeisenbis(sulfat) |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 179 |
|---|---|
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 8 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 13 |
| Formalladung | 0 |
| Komplexität | 62,2 |
| Stoffklassen | Metals -> Metals, Inorganic Compounds |
| Dichte | 1.86 at 68 °F (USCG, 1999) - Denser than waterwill sinkPale blue-green crystals or crystalline powder. Efforesces. Density: 1.86 at 20 °C/4 °C. /Ferrous ammonium sulfate hexahydrate/1.865 @25 °C |
| Löslichkeit | 26.9 G SOL IN 100 CC WATER @ 20 °C73 G SOL IN 100 CC WATER @ 80 °CINSOL IN ETHANOL. /FERROUS AMMONIUM SULFATE HEXAHYDRATE/soluble in H2Oinsoluble in ethanolg/100g H2O: 12.5 (0°C), 17.2 (10°C), 26.4 (20°C), 33 (30°C), 46 (40°C)insoluble alcohol [MER06] [LAN05] |
| Food Contact Substances | FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR |
| Brechungsindex | INDEX OF REFRACTION: 1.487, 1.492, 1.499 /FERROUS AMMONIUM SULFATE HEXAHYDRATE/ |
| Physical Description | Ferrous ammonium sulfate appears as a light green crystalline solid. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. It is used in medicine, chemical analysis and metallurgy.Light green crystals, deliquescent and soluble in water[CAMEO] |
| Stability/Shelf Life | Slowly oxidizes in air. /Ferrous ammonium sulfate hexahydrate/ |
| Other Experimental Properties | Decomposes at 100 to 110 °Cdeliquescentaffected by light. /Ferrous ammonium sulfate hexahydrate/Blue-green monoclinic crystals. /Ferrous ammonium sulfate hexahydrate/Sugar, glycerin, & many organic hydroxy acids hinder precipitation. In neutral solution, soluble carbonates, phosphates, & oxalates produce precipitation. /Ferrous salts/ |
| Schmelzpunkt | 100 °C |
| Lagerbedingungen | 15-25°C |
| Aggregatzustand | Liquid |
| Farbe | pale green |
| pH | 0.4 (20°C in H2O) |
| Merck | 13,523 |
| Kosmetik-Inhaltsstoffe Funktionen | ANTIMICROBIAL |
| CAS Datenbank | 10045-89-3(CAS DataBase Reference) |
| EPA chemische Informationen | Ferrous ammonium sulfate (10045-89-3) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 98.3% (171 of 174) of all reports.Not ClassifiedAggregated GHS information provided per 174 reports by companies from 5 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | Chemical: Sulfuric acid, ammonium iron(2+) salt (2:2:1)Status: Active Update: 09-12-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/24000Restricted substance: Diammonium iron bis(sulphate)Sulfuric acid, ammonium iron(II) salt: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - Sulfuric acid, ammonium iron(2+) salt (2:2:1): Human health tier I assessment |
| Brandgefahren | Special Hazards of Combustion Products: Irritating and toxic ammonia and oxides of nitrogen may form in fires. (USCG, 1999) |
| Brandpotenzial | Not flammable /Ferrous ammonium sulfate hexahydrate/ |
| Gesundheitsgefahren | Inhalation of dust irritates nose and throat. Ingestion causes irritation of mouth and stomach. Dust irritates eyes and can irritate skin on prolonged contact. (USCG, 1999) |
| Gefahrenübersicht | A skin and eye irritant[CAMEO] LD50 (rats) = 0.5-5 g/kg[HSDB] Could cause iron poisoning and liver damage if ingested[MSDSonline] See Iron, soluble compounds. |
| Reaktive Gruppe | Salts, Acidic |
| FIFRA-Anforderungen | As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA '88 were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Ferrous ammonium sulfate is found on List D. Case No: 4058Pesticide type: herbicideCase Status: //csrc//Active ingredient (AI): ferrous ammonium sulfateAI Status: The active ingredient is no longer contained in any registered products ... "cancelled." |
| OSHA Standards | Vacated 1989 OSHA PEL TWA 1 mg/cu m is still enforced in some states. /Iron salts (soluble, as Fe)/ |
| Reactivity Profile | FERROUS AMMONIUM SULFATE releases irritating and toxic ammonia and oxides of nitrogen if burned (USCG, 1999). |
| Air and Water Reactions | Soluble in water that forms weakly acidic solutions. Deliquesces in air. |
| Toxic Combustion Products | Irritating and toxic ammonia and oxides of nitrogen may form in fires. /Ferrous ammonium sulfate hexahydrate/ |
| Erste Hilfe | INGESTION: give large amount of waterinduce vomiting if large amounts have been swallowed. |
| Brandbekämpfungsverfahren | If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) |
| Lagerbedingungen | Keep well closed & protected from light. /Hexahydrate/ |
| Reinigungsverfahren | Environmental considerations: Water spill: Allow to aerate. Neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3). Adjust pH to neutral (pH+ 7). Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.Environmental considerations: Land spill: Big a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover soldis with a plastic sheet to prevent dissolving in rain or fire fighting water. |
| Entsorgungsverfahren | SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air qualitypotential migration in soil or watereffects on animal, aquatic, and plant lifeand conformance with environmental and public health regulations.The following wastewater treatment technologies have been investigated for iron (Fe+2): Concentration process: Biological treatment. /Iron (Fe+2)/ |
| Preventive Measures | SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.Remove contaminated clothing and shoes.For more Preventive Measures (Complete) data for FERROUS AMMONIUM SULFATE (7 total), please visit the HSDB record page. |
| Threshold Limit Values (TLV) | 1.0 [mg/m3], as Fe (soluble iron salts)8 hr Time Weighted Avg (TWA) 1 mg/cu m /Iron salts, soluble, as Fe/Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Iron salts, soluble, as Fe/ |
| Protective Action Criteria (PAC) | 15 [mg/m3]78 [mg/m3]470 [mg/m3] |
| Personal Protective Equipment (PPE) | Dust maskgoggles or face shieldprotective gloves (USCG, 1999)protective gloves. /Ferrous ammonium sulfate hexahydrate/ |
| Other Standards Regulations and Guidelines | Australia, Belgium, Finland, Italy, Netherlands, & Switzerland: 1 mg/cu m. /Iron salts/ |
| Unerwünschte Wirkungen | Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. |
| Human Toxicity Excerpts | /HUMAN EXPOSURE STUDIES/ Inhalation of dust irritates nose and throat. Ingestion causes irritation of mouth and stomach. Dust irritates eyes and can irritate skin on prolonged contact. |
| Non-Human Toxicity Excerpts | /ALTERNATIVE IN VITRO TESTS/ The effect of vitamin E deficiency on brain mitochondrial oxidative phosphorylation was studied using brain mitochondria isolated from control and vitamin E-deficient rats (13 months of deficiency) after exposure to iron, an inducer of oxidative stress. Mitochondria were treated with iron (2 to 50 microM) added as ferrous ammonium sulfate. Rates of state 3 and state 4 respiration, respiratory control ratios, and /the ratio of ADP molecules phosphorylated to oxygen atoms reduced/ (ADP/O) were not affected by vitamin E deficiency alone. However, iron uncoupled oxidative phosphorylation in vitamin E deficient mitochondria, but not in controls. In vitamin E deficient mitochondria, iron decreased ADP/O ratios and markedly stimulated state 4 respirationiron had only a modest effect on these parameters in control mitochondria. Thus, vitamin E may have an important role in sustaining oxidative phosphorylation. Low concentrations of iron (2 to 5 microM) oxidized mitochondrial tocopherol that exists in two pools. The release of iron in brain may impair oxidative phosphorylation, which would be exacerbated by vitamin E deficiency. |
| Antidote and Emergency Treatment | Maintain an open airway and assist ventilation if necessary. Treat shock caused by hemorrhagic gastrointestinitis aggressively with intravenous crystalloid fluids, and replace blood if needed. Patients are often markedly hypovolemic owing to gastrointestinal losses and third spacing of fluids into the intestinal wall and interstitial space. Treat coma, seizures, and metabolic acidosis if they occur. For seriously intoxicated victims (eg, shock, severe acidosis, and/or serum iron > 500-600 mcg/dL) administer deferoxamine. Monitor the urine for the urine for the characteristic orange or pink deferoxamine-iron complex. Therapy may be stopped when the urine returns to normal or when the serum iron level decreases to the normal range. Prolonged deferoxamine has been associated with adult respiratory distress syndrome and Yersinia sepsis.Activated charcoal is not effective. Ipecac is not recommended, because it can aggravate iron-induced gastrointestinal irritation and interfere with whole bowel irrigation. Consider gastric lavage if product was a liquid formulation or tablets were chewed. Do-not use phosphate-containing solutions for lavagethese may result in life-threatening hypernatremia, hyperphosphatemia, and hypocalcemia. Bicarbonate and deferoxamine lavage are of doubtful efficacy. Deferoxamine lavage is not effective and may enhance iron absorption. Whole-bowel irrigation is very effective for ingested tablets and may be considered first-line treatment, especially if large numbers of tablets are visible on plain abdominal x-ray. Massive ingestions may lead to concretions or bezoars. Repeated or prolonged whole-bowel irrigation may remove tablets. Endoscopy or surgical gastrotomy is rarely required.Hemodialysis and hemoperfusion are not effective for removing iron but may be necessary to remove iron-deferoxamine complex in patients with renal failure. Exchange transfusion is occasionally used for massive pediatric ingestions but is of questionable efficacy.Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. /Iron and related compounds/Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with lactated Ringer's /SRP: "To keep open", minimal flow rate/. Watch for signs of fluid overload. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Iron and related compounds/ |
| Non-Human Toxicity Values | LD50 Rat ingestion 0.5-5 g/kgLD50 Rat oral 3,250 mg/kg bw /Hexahydrate/ |
| CERCLA-Meldepflichtmengen | Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b). |
| Clean Water Act Anforderungen | Ferrous ammonium sulfate is designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. This designation includes any isomers and hydrates, as well as any solutions and mixtures containing this substance. |
| Bundesrichtlinien für Trinkwasser | EPA 300 ug/L /Iron/ |
| Wassergefährdungsklasse (WGK) | WGK 1 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 2796 8/PG 2 |
| R-Sätze (R) | 36/37/38-35 |
| Gefahrensymbole | Xi,C |
| Sicherheitshinweise (S) | 37/39-26-45-36/37/39-30 |
| Lagerklasse | 8B - Non-combustible, corrosive hazardous materials |
| Gefahrstoffdaten | 10045-89-3(Hazardous Substances Data) |
| Gefahrenklasse | Eye Dam. 1Met. Corr. 1Skin Corr. 1A |
Anwendungen & Verwendung
Verwenden
Iron ammonium sulfate is an analytical reagent in titrations and colori-metric measurements to measure oxidizing substances, such as chlorine, or tomeasure the chemical oxygen demand in waste water. The compound is usedto prepare Fe(II) standard solution for these analyses. It also is a calibration standard in magnetic measurements; a reducing agent; a catalyst for poly-merization; and is used in photographic chemistry.
Herstellung & Synthese
synthetische
Ferrous ammonium sulfate may be prepared by mixing an equimolar solution of ferrous sulfate and ammonium sulfate, followed by evaporation andcrystallization.