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Calcium Sulfate Dihydrate
GYPSUM · selenite · CALCIUM SULPHATE DIHYDRATE · CSD · pigment white 25 · gypse · CDB1 · CDG2
Identifikatoren & physikalische Daten
| CAS No. | 10101-41-4 |
|---|---|
| Summenformel | CaSO4.2H2O |
| Durchschnittliche Molmasse | 172,17 g/mol |
| Monoisotopische Masse | 171,93544983 g/mol |
| SMILES | O.O.O=S(=O)([O-])[O-].[Ca+2] |
| InChIKey | PASHVRUKOFIRIK-UHFFFAOYSA-L |
| PubChem CID | 24928 |
| ChEBI | CHEBI:32583 |
| EC No. | 600-148-1 |
| DTXSID | DTXSID7047514 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 90,6 |
|---|---|
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 62,2 |
| Stoffklassen | Mineral Dusts -> Other Mineral DustsMetals -> Metals, Inorganic Compounds |
| Dichte | 2.32 (NIOSH, 2024) - Denser than waterwill sink2.32 g/cm³ |
| Löslichkeit | 0.2 % at 77 °F (NIOSH, 2024)Solubility in water, g/100ml at 20 °C: 0.2 (very poor)(77 °F): 0.2%H2O: 0.01 M at 20 °C, clear, colorless2 g/L (20 ºC) |
| Animal Drugs | Pharmaceuticals -> UK Veterinary Medicines Directorate List |
| Schmelzpunkt | 262 to 325 °F (Loses H2O) (NIOSH, 2024)100-150 °C262-325 °F (loses H₂O)262-325 °F (Loses H2O)128°C -1.5H₂O |
| Dampfdruck | 0 mmHg (approx) (NIOSH, 2024) |
| Physical Description | Gypsum appears as white or nearly white, odorless, crystalline solid.Dry PowderOther SolidCBIWhite or nearly white, odorless, crystalline solidWhite to slightly yellowish-white odorless solid[Merck Index] Colorless hygroscopic solid[OECD SIDS: Calcium sulfate, dihydrate - 2003] White powder[Sigma-Aldrich MSDS]CRYSTALLINE POWDER. |
| Siedepunkt | 163°C -2H₂O |
| Flammpunkt | 163°C -2H₂O |
| Lagerbedingungen | Store at +5°C to +30°C. |
| Aggregatzustand | powder |
| Farbe | White |
| Wichte | 2.32 |
| pH | 7.0 (50g/l, H2O, 20℃)(slurry) |
| Geruch | at 100.00%. odorless |
| Merck | 14,1706 |
| Dielektrizitätskonstante | 2.5(Ambient) |
| Stabilität | Stable. Incompatible with aluminium, strong acids. |
| Kosmetik-Inhaltsstoffe Funktionen | COLORANTOPACIFYINGBULKINGABRASIVE |
| InChI | 1S/Ca.H2O4S.2H2O/c1-5(2,3)4/h(H2,1,2,3,4)2*1H2/q+2/p-2 |
| InChIKey | PASHVRUKOFIRIK-UHFFFAOYSA-L |
| SMILES | O.O.[Ca++].[O-]S([O-])(=O)=O |
| LogP (Verteilungskoeffizient) | -1.031 (est) |
| CAS Datenbank | 10101-41-4(CAS DataBase Reference) |
| NIST chemische Informationen | calcium sulfate(10101-41-4) |
| EPA chemische Informationen | Calcium sulfate dihydrate (10101-41-4) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 100% (278 of 278) of all reports.Not ClassifiedAggregated GHS information provided per 278 reports by companies from 2 notifications to the ECHA C&L Inventory.This chemical does not meet GHS hazard criteria for 100% (40 of 40) of all reports.Aggregated GHS information provided per 40 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | Chemical: Sulfuric acid, calcium salt, dihydrateDirective (EC) No 46/2002Gypsum (Ca(SO4).2H2O) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Gypsum (Ca(SO4).2H2O) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Sulfuric acid, calcium salt (1:1), dihydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfuric acid, calcium salt (1:1), dihydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Calcium sulfate dihydrate: Does not have an individual approval but may be used under an appropriate group standardGypsum (Ca(SO4).2H2O): Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
| Weitere Sicherheitsinformationen | IMAP assessments - Sulfuric acid, calcium salt, dihydrate: Human health tier I assessment |
| Brandgefahren | Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| Gesundheitsgefahren | Excerpt from NIOSH Pocket Guide for Gypsum: |
| Gefahrenübersicht | A cross-sectional study of 241 British gypsum miners in Sussex and Nottinghamshire with over 20 years of exposure identified x-ray findings consistent with a simple pneumoconiosis. Sixty-four miners had >1/0 on the ILO scale and 3 miners had 2/1 or greater. The authors attributed the higher rates of slight pneumoconiosis in the Sussex miners to the higher levels of quartz in these mines where the levels of gypsum dust were lower. [ACGIH] See Calcium sulfate.Not a skin irritant in rabbitsNo evidence of skin sensitization in guinea pigsDecreased total protein, albumin, BUN, AST, ALT, and creatinine observed in males at 300 and 1,000 mg/kg/day in repeated-dose oral study of rats (possible effect on excretion, distribution, or metabolism relating to the kidney)No adverse effects observed in females at dose up to 1,000 mg/kg/dayNo evidence of reproductive or developmental toxicity in rats at oral doses up to 1,000 mg/kg/dayNo evidence of mutagenicity[OECD SIDS: Calcium sulfate, dihydrate - 2003] May cause mechanical irritationRepeated or prolonged exposure to dust particles may cause lung effects[ICSC] May cause irritation[Sigma-Aldrich MSDS] See Calcium sulfate. See Gypsum. |
| Reaktive Gruppe | Non-Redox-Active Inorganic Compounds |
| Reactivity Profile | GYPSUM is generally of low reactivity. Can serve as an oxidizing agent under forcing conditions. Incompatible with aluminum (at high temperatures) and diazomethane. |
| Flammable Limits | Noncombustible Solid |
| Air and Water Reactions | No rapid reaction with air. No rapid reaction with water. |
| Hazard Classes and Categories | Not ClassifiedSpecific target organ toxicity - Single exposure - Category 3 (Respiratory tract irritation) |
| Hazardous Reactivities and Incompatibilities | Aluminum (at high temperatures), diazomethane |
| Brandbekämpfung | In case of fire in the surroundings, use appropriate extinguishing media. |
| Erste-Hilfe-Maßnahmen | Fresh air, rest.Rinse and then wash skin with water and soap.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. |
| Erste Hilfe | Excerpt from NIOSH Pocket Guide for Gypsum:(General first aid procedures) |
| Expositionsschutz und Persönliche Schutzausrüstung | 4.0 [mg/m3], (inhalable fraction), 1.5 mg/m3 (respirable fraction)[German Research Foundation (DFG)]4.0 [mg/m3](inhalable fraction), 1.5 mg/m3(respirable fraction)[German Research Foundation (DFG)] |
| Verschüttetes entsorgen | Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into containers. If appropriate, moisten first to prevent dusting. |
| Eye Prevention | Wear safety spectacles. |
| Inhalation Risk | A nuisance-causing concentration of airborne particles can be reached quickly when dispersed. |
| Ingestion Prevention | Do not eat, drink, or smoke during work. |
| Inhalation Prevention | Use local exhaust or breathing protection. |
| Respirator Recommendations | Important additional information about respirator selection |
| Threshold Limit Values (TLV) | 10.0 [mg/m3], inhalable fraction(inhalable fraction): 10 mg/m10 mg/m³ (inhalable particulate matter) [2005] |
| Effects of Long Term Exposure | Lungs may be affected by repeated or prolongated exposure to dust particles. |
| Zielorgane | Eyes, skin, respiratory system |
| Unerwünschte Wirkungen | Fibrogenic - Inducing tissue injury and fibrosis (scarring). |
| Expositionspfade | inhalation, skin and/or eye contact |
| Signs and Symptoms | Cough.Redness.irritation eyes, skin, mucous membrane, upper respiratory systemcough, sneezing, rhinorrhea (discharge of thin nasal mucus) |
| Berufliche Expositionsstufe (OEB) | B |
| Arbeitsplatzgrenzwert (OEL) | TWA: 5.0 mg/m3 |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | Yes |
| Zollcode | 28332990 |
| RTECS-Nr. | EW4150000 |
| R-Sätze (R) | 20/21/22-36/37/38 |
| Toxizität | LD50 orally in Rabbit: > 10000 mg/kg |
| Gefahrensymbole | Xn |
| Sicherheitshinweise (S) | 22-24/25-36-26 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
Calcium Sulfate Dihydrate is obtained from gypsum, a naturally occurring compound. Also used in the preparation of calcium sulfate and calcium sulfoaluminate.