Deslorelin acetate
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Grundinformationen
- CAS
82318-06-7- Standard-SMILES
CC(=O)O.CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1- InChIKey
LYCYLGFSIXIXAB-NUZRHMIVSA-N- Summenformel
- C66H87N17O14
- Durchschnittliche Molmasse
- 1.342,527 g/mol
- Monoisotopische Masse
- 1.341,66184046
Namen und Bezeichner
- Bevorzugter Name
- Deslorelin acetate
- IUPAC
- Acetic acid--5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (1/1)
- Englischer Name
- Deslorelin acetate
- Summenformel
- C66H87N17O14
- Molmasse
- 1342.50248
Namen und Synonyme
H 4065 AcetateSoMagard AcetaPTL 3001 AcetateBacheM 9022 AcetateD-Trp LHRH-PEA AcetateDeslorelin MonoacetateDeslorelin Acetate(acetate)D-Trp6-Pro9-N-ethylaMide-LH-RH Acetate6-D-Tryptophan-9-(N-ethyl-L-prolinaMide)-1-9-luteinizing HorMone-releasing Factor (Swine) Monoacetate
Datenbank-Bezeichner
- CAS
82318-06-7- PubChem CID
- 25077533
- DTXSID
DTXSID1046683- ChEMBL
CHEMBL2357192- UNII
- 679007NR5C
Chemie und Industrie
Anwendungen
BeschreibungDeslorelin Acetate is a synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production.
VerwendenDeslorelin acetate is an injectable gonadotropin-releasing hormone (GnRH) super-agonist (also known as an LHRH agonist), used in treatment of precocious puberty and commonly used in veterinary medicine to induce ovulation in mares.
Darstellung
synthetischeDeslorelin acetate is synthesized from the corresponding protected amino acid monomers by solid or liquid phase synthesis.
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上海沛灵生物科技有限公司13127581762 13127581762 · [email protected]
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