Oxcarbazepine-d4
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
1134188-71-8- Standard-SMILES
[2H]c1c([2H])c([2H])c2c(c1[2H])C(=O)Cc1ccccc1N2C(N)=O- InChIKey
CTRLABGOLIVAIY-MNYIHESISA-N- Summenformel
- C15H12N2O2
- Durchschnittliche Molmasse
- 256,2974 g/mol
- Monoisotopische Masse
- 256,11498461
Namen und Bezeichner
- Bevorzugter Name
- Oxcarbazepine-d4
- IUPAC
- 10-Oxo(6,7,8,9-~2~H_4_)-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
- Englischer Name
- OXCARBAZEPINE-D4
- Summenformel
- C15H8D4N2O2
- Molmasse
- 256.29
Namen und Synonyme
TRILEPTAL-D4OXCARBAZEPINE-D4D4-OxcarbazepineOxcarbazepine-6,7,8,9-d4 (Aniline-6,7,8,9-d4)10,11-DIHYDRO-10-OXO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE-D410,11-dihydro-11-oxo-5H-dibenz[b,f]azepine-1,2,3,4-d4-5-carboxamide1,2,3,4-tetradeuterio-5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide9-oxo(4,5,6,7-2H?)-2-azatricyclo[9.4.0.03,?]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxamide
Datenbank-Bezeichner
- CAS
1134188-71-8- PubChem CID
- 25235654
- DTXSID
DTXSID50649423
Eigenschaften
Physikochemische Eigenschaften
- Siedepunkt
- 457.236 · 457.236±55.00 °C(Press: 760.00 Torr)(predicted)
- Dichte
- 1.329 · 1.329±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- DMSO: soluble
- Aggregatzustand
- A solid
- pka
- 13.733 · 13.733±0.20(predicted)
Chemie und Industrie
Anwendungen
BeschreibungOxcarbazepine-d4 is intended for use as an internal standard for the quantification of oxcarbazepine by GC- or LC-MS. Oxcarbazepine is a prodrug form of the antiepileptic compound 10,11-dihydro-10-hydroxy carbamazepine . It inhibits high-frequency repetitive firing of rat spinal cord neurons when used at a concentration of 1 μM. Oxcarbazepine protects against electroshock-induced tonic hindlimb extension (ED50s = 10-20 mg/kg), as well as seizures induced by pentylenetetrazole (PTZ; ) or picrotoxin in rodents (ED50s = 23-30 and 150-250 mg/kg, respectively). Formulations containing oxcarbazepine have been used in the treatment of epileptic seizures.
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…