N-(Trimethylsilyl)acetamid

Acetamide, N-(trimethylsilyl)-

HCID 25989

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Grundinformationen

CAS: 13435-12-6
Standard-SMILES: CC(=O)N[Si](C)(C)C
InChIKey: LWFWUJCJKPUZLV-UHFFFAOYSA-N
Summenformel: C5H13NOSi
Durchschnittliche Molmasse: 131,25 g/mol
Monoisotopische Masse: 131,07664057

Namen und Bezeichner

Bevorzugter Name: Acetamide, N-(trimethylsilyl)-
IUPAC: N-trimethylsilylacetamide
Lokaler Name: N-(Trimethylsilyl)acetamid
Englischer Name: N-(Trimethylsilyl)acetamide
Summenformel: C5H13NOSi
Molmasse: 131.25

Namen und Synonyme

N-(Trimethylsilyl)acetamide13435-12-6N-TrimethylsilylacetamideACETAMIDE, N-(TRIMETHYLSILYL)-Trimethylsilylacetamide(Acetylamino)trimethylsilaneEINECS 236-565-7NSC 139859BRN 0741928DTXSID80654544-04-00-04011 (Beilstein Handbook Reference)RefChem:551795

Weitere Namen anzeigen

trimethylsilylTMSACMH3DK063CMD1YLVNC9C15orf13HEL-S-265HTM-alpha

DTXCID2034205236-565-7C5H13NOSiAcetamide, TMS derivativeMFCD00008671n-trimethylsilyl-acetamideTMS acetamideS18875

Datenbank-Bezeichner

CAS: 13435-12-6
PubChem CID: 25989
DTXSID: DTXSID8065454
EC Number: 236-565-7
Nikkaji: J55.333F

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA): 29,1 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 1
Frei drehbare Bindungen: 1
Schwere Atome: 8
Formalladung: 0
Komplexität: 95

Physikochemische Eigenschaften

Schmelzpunkt: 46 · 46-49 °C(lit.)
Siedepunkt: 84 °C18 · 84 °C18 mm Hg(lit.)
Dichte: 0.859 · 0.859±0.06 g/cm3(Predicted)
Flammpunkt: 135 °F · 135 °F
storage temp.: Inert atmosphere,Room Temperature
Löslichkeit: Chloroform, DMSO, Methanol
pka: 18.23 · 18.23±0.46(Predicted)
Aggregatzustand: Crystalline Mass
Farbe: White to yellow
Wasserlöslichkeit: reacts
BRN: 741928 · 741928
Stabilität: Moisture Sensitive
InChI: 1S/C5H13NOSi/c1-5(7)6-8(2,3)4/h1-4H3,(H,6,7)
InChIKey: LWFWUJCJKPUZLV-UHFFFAOYSA-N
SMILES: CC(=O)N[Si](C)(C)C
CAS Datenbank: 13435 · 13435-12-6(CAS DataBase Reference)
EPA chemische Informationen: Acetamide, N-(trimethylsilyl)- (13435-12-6)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 84.4% (38 of 45) of all reports.

Warning

H315 (11.1%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (11.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 38 of 45 reports by companies.；There are 4 notifications provided by 7 of 45 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Chemical: Acetamide, N-(trimethylsilyl)-

Acetamide, N-(trimethylsilyl)-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Irrit. 2 (11.1%)；Eye Irrit. 2 (11.1%)

Regulatorische Informationen

Regulatory Information · 2 Einträge

Chemical: Acetamide, N-(trimethylsilyl)-

Acetamide, N-(trimethylsilyl)-: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

F: 10-21
wgk: 3
tsca: TSCA listed
ridadr: 1325
hs_code: 29319090
RTECS-Nr.: AD0250000
risk_code: 36/37/38-11
hazard_code: Xi-F,Xi,F
safety_code: 37/39-26
hazard_class: 4.1
packing_group: III
Speicherklasse: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing InformationAcetamide, N-(trimethylsilyl)-: ACTIVE

Anwendungen

VerwendenN-Trimethylsilylacetamide is a silylating agent used in organic synthesis. N-Trimethylsilylacetamide is used in the preparation of the antibacterial agent Cefdinir (C242670).