HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Bromoestra-1(10),2,4-triene-3,17-diol
2-Bromo 17β-Estradiol · 2-Bromo 17b-Estradiol · 2-Bromo 17-beta-Estradiol · 2-BroMo-1,3,5(10)-estratriene-3,17b-diol · Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)- · 2-bromo-, (17b)-Estra-1,3,5(10)-triene-3,17-diol,2-bromo- · (8R,9S,13S,14S)-2-bromo-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol · 2-Bromoestradiol,(13S,17S)-2-bromo-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Identifikatoren & physikalische Daten
| CAS No. | 15833-07-5 |
|---|---|
| Summenformel | C18H23BrO2 |
| Durchschnittliche Molmasse | 351,284 g/mol |
| Monoisotopische Masse | 350,08814208 g/mol |
| SMILES | CC12CCC3c4cc(Br)c(O)cc4CCC3C1CCC2O |
| InChIKey | SORISAYAZBCIQH-UHFFFAOYSA-N |
| PubChem CID | 266713 |
| DTXSID | DTXSID80935902 |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 190-193°C |
|---|---|
| Siedepunkt | 447.338±45.00 °C(Press: 760.00 Torr)(predicted) |
| Dichte | 1.412±0.06 g/cm3(Temp: 25 °CPress: 760 Torr)(predicted) |
| Lagerbedingungen | Amber Vial, Refrigerator |
| Löslichkeit | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 8.754±0.60(predicted) |
| Farbe | White to Off-White |
| Stabilität | Light Sensitive |
Sicherheit & Vorschriften
| Alarmwort | Achtung |
|---|---|
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302 |
Anwendungen & Verwendung
Verwenden
17β-Estradiol (E888000) metabolite. An inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells.