Levamisol

LEVAMISOLE BASE · (S)-6-phenyl-2,3,5,6-tetrahydroiMidazo[2,1-b]thiazole · lepuron · levomysol · Ketrax · LEVAMISOLE · l-tetramisole · (?)-Levamisole

https://huagongshe.com/de/chemical/26879

Identifikatoren & physikalische Daten

CAS No.	14769-73-4
Summenformel	C11H12N2S
Durchschnittliche Molmasse	204,29 g/mol
Monoisotopische Masse	204,07211956 g/mol
SMILES	c1ccc([C@H]2CN3CCSC3=N2)cc1
InChIKey	HLFSDGLLUJUHTE-SNVBAGLBSA-N
PubChem CID	26879
ChEMBL	CHEMBL1454
ChEBI	CHEBI:6432
EC No.	238-836-5
DTXSID	DTXSID4023206
Lokaler Name	Levamisol

Chemische & physikalische Eigenschaften

XLogP	1,8
Polarare Oberfläche (TPSA)	40,9
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	2
Frei drehbare Bindungen	1
Schwere Atome	14
Formalladung	0
Komplexität	246
Schmelzpunkt	60-61.5°
Siedepunkt	344.4±45.0 °C(Predicted)
Dichte	1.32±0.1 g/cm3(Predicted)
Lagerbedingungen	Sealed in dry,2-8°C
Löslichkeit	Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand	Solid
pKa (Säurekonstante)	10.00±0.40(Predicted)
Farbe	Off-White to Pale Yellow
InChI	InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1
InChIKey	HLFSDGLLUJUHTE-SNVBAGLBSA-N
SMILES	S1CCN2C[C@H](C3=CC=CC=C3)N=C12
CAS Datenbank	14769-73-4(CAS DataBase Reference)
EPA chemische Informationen	Levamisole (14769-73-4)

Sicherheit & Vorschriften

Alarmwort	Warnung
Gefahrenhinweise	Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H315

Anwendungen & Verwendung

Verwenden

Levamisole is used for initial and secondary immunodeficient conditions, autoimmune diseases, chronic and reoccurring infections, large intestine adenocarcinoma, helmintosis, and rheumatoid arthritis. Synonyms of this drug are decaris, tetramizole, and others.Levimasole is also a drug of choice for ascardiasis. Numerous investigations show that a single dose of levamisole heals from 90 to 100% of patients with ascardiasis, in particular those infected with A. duodenale. It is less effective against ancylostomiasis and strongyloidiasis. However, it is not effective against N. americanus. It seems likely that it has a gangliostimulating effect on parasite tissues in both the parasympathetic and sympathetic regions. Moreover, it is presumed that this drug has an immunomodulatory effect on the host organism. Synonyms of this drug are decaris, solacil, ergamisol, tramisol, immunol, and others.