Grundinformationen
- CAS
477-73-6- Standard-SMILES
Cc1cc2nc3cc(C)c(N)cc3[n+](-c3ccccc3)c2cc1N.[Cl-]- InChIKey
OARRHUQTFTUEOS-UHFFFAOYSA-N- Summenformel
- C20H19N4.Cl
- Durchschnittliche Molmasse
- 350,8 g/mol
- Monoisotopische Masse
- 350,1298243
Überblick
Safranin O is an organic chloride salt having 3,7-diamino-2,8-dimethyl-5-phenylphenazin-5-ium as the counterion. It is commonly used for staining Gram negative bacteria. It has a role as a fluorochrome and a histological dye. It contains a 3,7-diamino-2,8-dimethyl-5-phenylphenazin-5-ium.
Namen und Bezeichner
- Bevorzugter Name
- C.I. Basic Red 2
- IUPAC
- 3,7-dimethyl-10-phenylphenazin-10-ium-2,8-diamine chloride
- Lokaler Name
- 3,7-Diamino-2,8-dimethyl-5-phenylphenaziniumchlorid
- Englischer Name
- Basic Red 2
- Summenformel
- C20H19ClN4
- Molmasse
- 350.85
Namen und Synonyme
477-73-6BASIC RED 2SafraninSafranine OSafranine TSafranin TGossypimineC.I. Basic Red 2Safranine ZhSafranine ASafranine THSafranine
Weitere Namen anzeigen
SAFRANIN OSAFRANIN SOLUTIONS NO 967CI 50240Saffron TSAFRANIN Y
Safranine BSafranine GSafranine JSafranine YSafranine GFSafranine OKSafranine TNSafranine TS
Datenbank-Bezeichner
- CAS
477-73-6- PubChem CID
- 2723800
- DTXSID
DTXSID60874047- ChEMBL
CHEMBL5195997- ChEBI
CHEBI:197447- UNII
- XTX0YXU2HV
- EC Number
- 207-518-8
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 68,8 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 1
- Schwere Atome
- 25
- Formalladung
- 0
- Komplexität
- 405
Experimentelle und physikochemische Eigenschaften
Chemical ClassesDyes -> Azine Dyes
CosmeticsHair dyeing
Physical DescriptionDark brown solid; [MSDSonline]
Other Experimental PropertiesCATIONIC
Physikochemische Eigenschaften
- Schmelzpunkt
- 240 ℃ · >240℃ (decompose)
- Siedepunkt
- 507.14 °C · 507.14°C (rough estimate)
- Dichte
- 1 g/mL · 1.00 g/mL at 20 °C
- Brechungsindex
- 20 · n20/D 1.339
- Flammpunkt
- 46 °C · 46 °C
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Löslichkeit
- 2 O: · H2O: soluble1mg/mL
- Aggregatzustand
- Solid
- pka
- 6.4 · 6.4(at 25℃)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 2.8% (2 of 71) of reports.
Danger
H315 (16.9%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)
Aggregated GHS information provided per 71 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: Phenazinium, 3,7-diamino-2,8-dimethyl-5-phenyl-, chloride
Safranine T: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Chemicals with limited data availability that may be used in hair dyes in Australia: Human health tier II assessment
Hazards SummaryMay cause injury to eyes; [HSDB] An irritant; May cause permanent eye damage; [MSDSonline]
Hazard Classes and CategoriesSkin Irrit. 2 (16.9%)
Sicherheit und Schutzausrüstung
Protective Action Criteria (PAC)
0.17 [mg/m3]
1.9 [mg/m3]
11 [mg/m3]
Toxikologische Informationen
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.
Absorption, Distribution and Excretion...CATIONIC DYES PENETRATE INTO CELLS & STAIN CELL NUCLEI MORE READILY THAN DO ANIONIC DYES.
Verwendung und Herstellung
Uses
Used as a dye; [HSDB] Azine dye; [Kirk-Othmer] An azine dye used to dye leather; [Ullmann]
Leather Tanning and Processing [Category: Industry]
DYES
Use ClassificationCosmetics -> Hair dyeing
General Manufacturing Information
Phenazinium, 3,7-diamino-2,8-dimethyl-5-phenyl-, chloride (1:1): ACTIVE
COSMETIC PREPARATIONS--LIPSTICKS MAY CONTAIN SAFRANIN /FROM TABLE/
Anwendungen
VerwendenIn forensics to visualize details of cyanoacrylate-fumed friction ridges of human digits.
Darstellung
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