(S)-6-(p-Bromphenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoloxalat
(-)-p-Bromotetramisole oxalate
Grundinformationen
- CAS
62284-79-1- Standard-SMILES
Brc1ccc([C@H]2CN3CCSC3=N2)cc1.O=C(O)C(=O)O- InChIKey
ZULBIBHDIQCNIS-HNCPQSOCSA-N- Summenformel
- C13H13BrN2O4S
- Durchschnittliche Molmasse
- 373,22 g/mol
- Monoisotopische Masse
- 371,97794
Namen und Bezeichner
- Bevorzugter Name
- (-)-p-Bromotetramisole oxalate
- IUPAC
- (6S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;oxalic acid
- Lokaler Name
- (S)-6-(p-Bromphenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoloxalat
- Englischer Name
- (-)-4-Bromotetramisole oxalate
- Summenformel
- C13H13BrN2O4S
- Molmasse
- 373.22
Namen und Synonyme
(-)-p-Bromotetramisole oxalateRefChem:390986L-p-BROMOTETRAMISOLE OXALATES(-)-p-Bromotetramisole oxalate(S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate(-)-4-Bromotetramisole oxalate(S)-(-)-4-Bromotetramisole oxalate(-)-p-Bromotetramisole (oxalate)(-)-p-Bromolevamisole oxalateL-(-)-p-Bromotetramisole oxalate(6S)-6-(4-BROMOPHENYL)-2H,3H,5H,6H-IMIDAZO[2,1-B][1,3]THIAZOLE; OXALIC ACIDC13H13BrN2O4S
Weitere Namen anzeigen
(S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalateR 304026-BROMOLEVAMISOLE OXALATEBromotetramisole, L(-) oxalate
R 30402 oxalateEU-0100021()-p-Bromolevamisole oxalateBMK1-H3MLS000860040orb1221538orb1300842CHEMBL1256792
Datenbank-Bezeichner
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 116 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 6
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 21
- Formalladung
- 0
- Komplexität
- 345
Physikochemische Eigenschaften
- Schmelzpunkt
- 192 °C · 192 °C (dec.) (lit.)
- Flammpunkt
- Not applicable
- storage temp.
- 2 · 2-8°C
- Löslichkeit
- Soluble in Water (up to 10 mg/ml)
- Aggregatzustand
- powder
- Farbe
- White
- BRN
- 4944883 · 4944883
- Stabilität
- 1 year · Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
- InChI
- InChI=1/C11H11BrN2S.C2H2O4/c12-9-3-1-8(2-4-9)10-7-14-5-6-15-11(14)13-10;3-1(4)2(5)6/h1-4,10H,5-7H2;(H,3,4)(H,5,6)/t10-;/s3
- InChIKey
- ZULBIBHDIQCNIS-MEQOOBBNNA-N
- SMILES
- C(=O)(O)C(=O)O.BrC1C=CC([C@@H]2N=C3SCCN3C2)=CC=1 |&1:11,r|
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- F
- 10
- wgk
- 3
- risk_code
- 21/22-36/37/38-20/21/22
- hazard_code
- Xn
- safety_code
- 24/25-36/37/39-26
- Speicherklasse
- 11 - Combustible Solids
- Hazard Classifications
- Acute Tox. 4 DermalAcute Tox. 4 Oral
Chemie und Industrie
Anwendungen
BeschreibungFour distinct human isoenzymes of alkaline phosphatase (AP) are known: intestinal (IAP), placental (PLAP), tissue non-specific (NSAP, also known as liver/bone/kidney AP), and germ cell AP (also known as placental-like AP, PLAP-like). L-p-Bromotetramisole is a cell-permeable inhibitor of all four human AP isoenzymes (Kis =18 and 56 μM for PLAP and NSAP, respectively). While PLAP is strongly inhibited by L-p-bromotetramisole, a second AP, possibly PLAP-like, shows only partial inhibition. L-p-Bromotetramisole has been shown to inhibit a tyrosine phosphatase from Drosophila and, as a result, is also used as a tyrosine phosphatase inhibitor.
Anbieter73 Anbieter
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
湖北研科时代科技有限公司15780669880 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
湖北威德利化学试剂有限公司17771473825 13385289472 · [email protected]
上海颖心实验室设备有限公司021-59178156 17002132182 · [email protected]
大连美仑生物技术有限公司0411-62910999 13889544652 · [email protected]
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