Natrium-4-(2-hydroxyethyl)piperazin-1-ylethansulfonat
Sodium 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethanesulfonate
Grundinformationen
- CAS
75277-39-3- Standard-SMILES
O=S(=O)([O-])CCN1CCN(CCO)CC1.[Na+]- InChIKey
RDZTWEVXRGYCFV-UHFFFAOYSA-M- Summenformel
- C8H17N2NaO4S
- Durchschnittliche Molmasse
- 260,29 g/mol
- Monoisotopische Masse
- 260,08067248
Namen und Bezeichner
- Bevorzugter Name
- Sodium 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethanesulfonate
- IUPAC
- sodium 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonate
- Lokaler Name
- Natrium-4-(2-hydroxyethyl)piperazin-1-ylethansulfonat
- Englischer Name
- HEPES sodium salt
- Summenformel
- C8H19N2NaO4S
- Molmasse
- 261.3
Namen und Synonyme
75277-39-3Sodium 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethanesulfonate103404-87-1sodium 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonateHEPES (sodium)4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid hemisodium saltZ9FTO91O8A1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium saltUNII-Z9FTO91O8AC8H17N2NaO4SMFCD00036463hepes sodium
Weitere Namen anzeigen
HEPES NAHEPES SODIUM SALT BUFFERHEPES, SODIUMH7006-500G(HEPES)2-NAHEPES NA-SALTRUTHENIUM STANDHEPES LOWSODIUMHEPES SODIUM SALT1.0 M HEPES sodium
4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid sodium saltDTXSID4044458Sodium 4-(2-hydroxyethyl)piperazin-1-ylethanesulphonatesodium;2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonateEINECS 278-169-71-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1)AKOS015897769FT-0610868
Datenbank-Bezeichner
- CAS
75277-39-3- PubChem CID
- 2724248
- DTXSID
DTXSID4044458- ChEMBL
CHEMBL3187284- ChEBI
CHEBI:46758- UNII
- Z9FTO91O8A
- EC Number
- 278-169-7
- Nikkaji
- J307.551F
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 92,3 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 6
- Frei drehbare Bindungen
- 5
- Schwere Atome
- 16
- Formalladung
- 0
- Komplexität
- 272
Experimentelle und physikochemische Eigenschaften
Physical Description
Dry Powder
White powder; [Sigma-Aldrich MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 234 °C · 234 °C
- Dichte
- 1.504 · 1.504[at 20℃]
- Dampfdruck
- 0 Pa · 0Pa at 25℃
- storage temp.
- room temp
- Löslichkeit
- 2 O: · H2O: 1 M at 20 °C, clear, colorless
- Aggregatzustand
- dry powder
- Farbe
- White
- PH
- 10 · 10.0-12.0 (1M in H2O)
- pka
- 7.5 · 7.5(at 25℃)
- Biologische Quelle
- synthetic
- Wasserlöslichkeit
- It is soluble in water.
- Stabilität
- Stable. Hygroscopic - protect from moisture. Incompatible with strong oxidizing agents.
- InChI
- 1S/C8H18N2O4S.Na.H2O/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;;/h11H,1-8H2,(H,12,13,14);;1H2/q;+1;/p-1
- InChIKey
- ZNJHFNUEQDVFCJ-UHFFFAOYSA-M
- SMILES
- O.[Na+].OCCN1CCN(CC1)CCS([O-])(=O)=O
- CAS Datenbank
- 75277 · 75277-39-3(CAS DataBase Reference)
- EPA chemische Informationen
- 1 · 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt (75277-39-3)
- Absorption
- 0.2 at · ≤0.2 at 260 in H2O at 1M≤0.2 at 280 in H2O at 1M
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 98.8% (160 of 162) of all reports.
Not Classified；Reported as not meeting GHS hazard criteria by 160 of 162 companies (only 1.2% companies provided GHS information). For more detailed information, please visit ECHA C&L website.
Aggregated GHS information provided per 162 reports by companies from 3 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 160 of 162 reports by companies.；There is 1 notification provided by 2 of 162 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Gefahrenhinweise
Regulatory Information
Chemical: 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt
1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Status: Active Update: 08-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/21261
1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS] See Piperazine and salts. See HEPES.
Hazard Classes and CategoriesNot Classified
Regulatorische Informationen
Regulatory Information
Chemical: 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt
1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Status: Active Update: 08-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/21261
1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Sicherheitsdaten
- F
- 3-10
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29335995
- safety_code
- 22-24/25
- Speicherklasse
- 13 - Non Combustible Solids
Chemie und Industrie
Verwendung und Herstellung
UsesA dipolar ionic buffer. [ChemIDplus]
U.S. Production2023: 28,556 lb
Consumer UsesStabilizing agent
Industry UsesStabilizing agent
General Manufacturing Information
Pharmaceutical and Medicine Manufacturing
1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1): ACTIVE
Anwendungen
VerwendenHEPES sodium salt solution is suitable for cell culture studies. It may be used in the preparation of buffer solution of HEPES. It may be used as buffer during the phosphorylation assays in permeabilized fibroblasts. It may be used to compose a complex dialysis buffer, used in the determination of free thyroxin in serum by radioimmunoassay.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Anbieter100 Anbieter
北京华美互利生物化工010-56205725 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]
上海将来实业股份有限公司400-0066400 13621662912 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
北京华威锐科化工有限公司0757-86329057 18934348241 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
大连美仑生物技术有限公司0411-62910999 13889544652 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
上海钰康生物科技有限公司+86-18930848214 +86-021-56762820 · [email protected]
上海泰坦科技股份有限公司400-6009262 15618770481 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
Xiamen AmoyChem Co., Ltd+86-86-5926051114 · [email protected]
湖南汇百侍生物科技有限公司0731-85526065 13308475853 · [email protected]
南京化学试剂股份有限公司025-58369808 17895012682 · [email protected]
斯百全化学（上海）有限公司021-021-021-67601398-809-809-809 15221380277 · [email protected]
上海源叶生物科技有限公司13636370518 · [email protected]
艾科试剂4008-755-333 18080918076 · [email protected]
南京爱莉生物科技有限公司025-83208295 18913388297 · [email protected]
赛默飞世尔科技（中国）有限公司800-810-5118 · [email protected]
上海遐瑞医药科技有限公司+86 21 61551611
上海贤鼎生物科技有限公司4009209199 · [email protected]
南京杜莱生物技术有限公司025-84699383-8003;025-846993838003-8003 18013301590 · [email protected]
上海倍卓生物科技有限公司021-61119791,13386096464 · [email protected]
上海将来实业股份有限公司400-0066400 13621662912 · [email protected]
上海将来实业股份有限公司021-61552785 · [email protected]
HBCChem, Inc.+1-510-219-6317 · [email protected]
苏州朗行生物科技有限公司0512-62968256 18550502935 · [email protected]
上海创赛科技有限公司400-6087598 15021221957 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
湖北巨胜科技有限公司027-59599241 18871490274 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
TargetMol中国（陶术生物）021-021-33632979 15002134094 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
北京诺其雅盛生物科技有限公司4000-819-385 010-62329685 13718666987
上海皓之翔生物科技有限公司（原上海拓青化工有限公司）526763801 13301653310 · [email protected]
厦门志信化学有限公司+86-5922680277 +86-13806087780 · [email protected]
湖南汇百益新材料有限公司400-0909710 13319523173 · [email protected]
湖南恒飞生物医药股份有限公司0746-6222194 13874779848 · [email protected]
SINOPRO.CO.LTD0082-42-721-7177 · [email protected]
浙江海强化工有限公司0571-86050367 0571-86960370 0571-86050387 · [email protected]
成都润泽本土化工有限公司028-88469284 18000562381 · [email protected]
上海炎泽化工有限公司15345144255 19901447308 · [email protected]
Zugehörige Reaktionen
1
Notizen zur Verbindung
Wird geladen…