HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(S)-(+)-gamma-Hydroxymethyl-gamma-butyrolactone
5-(Hydroxymethyl)dihydro-2(3H)-furanone · (S)-(+)-γ-Hydroxymethyl-γ(S)-Gamma-Hydroxymethyl-Gamma · (S)-4-HYDROXYMETHYL BUTYROLACTONE · (5S)-5-(hydroxyMethyl)oxolan-2-one · (s)-γ-hydroxymethyl-γ-butyrolactone · (S)-5-Hydroxymethyldihydrofuran-2-on · (S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE · (S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE
Identifikatoren & physikalische Daten
| CAS No. | 32780-06-6 |
|---|---|
| Summenformel | C5H8O3 |
| Durchschnittliche Molmasse | 116,11 g/mol |
| Monoisotopische Masse | 116,04734412 g/mol |
| SMILES | O=C1CC[C@@H](CO)O1 |
| InChIKey | NSISJFFVIMQBRN-BYPYZUCNSA-N |
| PubChem CID | 2733813 |
| EC No. | 680-050-3 |
| DTXSID | DTXSID00954438 |
Chemische & physikalische Eigenschaften
| XLogP | -0,4 |
|---|---|
| Polarare Oberfläche (TPSA) | 46,5 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 99,8 |
| Schmelzpunkt | 72-74 °C |
| Siedepunkt | 110-115 °C/0.2 mmHg (lit.) |
| Dichte | 1.237 g/mL at 25 °C (lit.) |
| Brechungsindex | 1.47 |
| Flammpunkt | 113 °C - closed cup |
| Lagerbedingungen | 2-8°C |
| pKa (Säurekonstante) | 14.12±0.10(Predicted) |
| Aggregatzustand | clear liquid |
| Farbe | Colorless to Almost colorless |
| BRN | 1680284 |
| InChI | 1S/C5H8O3/c6-3-4-1-2-5(7)8-4/h4,6H,1-3H2/t4-/m0/s1 |
| InChIKey | NSISJFFVIMQBRN-BYPYZUCNSA-N |
| SMILES | OC[C@@H]1CCC(=O)O1 |
| CAS Datenbank | 32780-06-6(CAS DataBase Reference) |
| NIST chemische Informationen | (S)-(+)-2',3'-dideoxyribonolactone(32780-06-6) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302 (94.7%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P270, P273, P301+P317, P330, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 19 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (94.7%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29322090 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 23-24/25-37/39-26 |
| Lagerklasse | 10 - Combustible liquids |
Anwendungen & Verwendung
Verwenden
(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone can be used as a chiral synthon to synthesize:Potent nucleoside, acetylcholine, and (+)-muricatacin analogs.Mevinic acids, which are LDL cholesterol-lowering agents.Adenine based anti-HIV agent named β-F-ddA.