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(2,6-Difluoropyridin-3-yl)boronic acid
(2,6-DIFLUOROPYRIDIN-3-YL)BORONIC ACID · uoropyridine-3-boronic acid · 3-Borono-2,6-difluoropyridine · 2,6-DIFLUOROPYRIDINE-3-BORONIC · 2,6-Difluoropyridine-3-boronicaci · 2,6-DIFLUOROPYRIDINE-3-BORONIC ACID · 2,6-DIFLUORO-3-PYRIDYL BORONIC ACID · (2,6-DIFLUORO-3-PYRIDINYL)-BORONIC ACID
Identifikatoren & physikalische Daten
| CAS No. | 136466-94-9 |
|---|---|
| Summenformel | C5H4BF2NO2 |
| Durchschnittliche Molmasse | 158,9 g/mol |
| Monoisotopische Masse | 159,0303149 g/mol |
| SMILES | OB(O)c1ccc(F)nc1F |
| InChIKey | LCCZTROJRJFXNV-UHFFFAOYSA-N |
| PubChem CID | 2762713 |
| EC No. | 681-155-7 |
| DTXSID | DTXSID90376387 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 53,4 |
|---|---|
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 11 |
| Formalladung | 0 |
| Komplexität | 138 |
| Schmelzpunkt | 168 °C(Solv: ethyl acetate (141-78-6)ethyl ether (60-29-7)) |
| Siedepunkt | 314.8±52.0 °C(Predicted) |
| Dichte | 1.44±0.1 g/cm3(Predicted) |
| Lagerbedingungen | Inert atmosphere,2-8°C |
| Löslichkeit | Soluble in water |
| Aggregatzustand | powder to crystal |
| pKa (Säurekonstante) | 6.77±0.58(Predicted) |
| Farbe | White to Light yellow |
| InChIKey | LCCZTROJRJFXNV-UHFFFAOYSA-N |
| CAS Datenbank | 136466-94-9(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (85.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 7 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%)Eye Irrit. 2A (100%)STOT SE 3 (85.7%) |
| Zollcode | 29333990 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-37 |
Anwendungen & Verwendung
Verwenden
2,6-Difluoropyridine-3-boronic acid is a pyridine analogue containing a fluorine atom reactive group and boronic acid in its structure. It can be used as a reagent for fluorination or substitution reactions and as a synthetic intermediate for the preparation of other organic compounds.